NFL Week 1 Predictions 2023: Picks & Odds for ALL Games

Rounding up our best NFL picks and predictions for Week 1. ML, ATS, O/U, and prop plays for a big payday.

Week 1 of the 2023 NFL season is underway and we're rounding up all of our experts' top NFL picks and predictions to help you start your betting campaign on the right foot!

The NFL kicked off its 2023 season with Thursday Night Football between the Detroit Lions and reigning Super Bowl champion Kansas City Chiefs, with the Lions stealing a shocking road victory.

We have 15 more games to go, culminating with the Buffalo Bills visiting the Aaron Rodgers-led New York Jets on Monday Night Football. We've had all summer to assess the NFL opening odds and betting lines for the 2023 season, and now it's time to make our best predictions based on the NFL odds from our best NFL betting sites.

NFL picks and predictions for Week 1

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NFL Week 1 picks: Sunday

Cowboys vs. Giants +3.5 pick (-115 via FanDuel) ⭐⭐⭐

Pick made by Mike Spector

NFL Week 1 picks: Monday

Bills vs. Jets ML pick (+125 via BetRiversbet365) ⭐⭐⭐

Pick made by Mike Spector

NFL Week 1 betting promos

NFL Week 1 expert picks

NFL betting odds pages

Check out our best NFL betting sites:

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