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Christian McCaffrey #23 of the San Francisco 49ers is featured in our NFL rushing yards odds
Christian McCaffrey #23 of the San Francisco 49ers runs the ball for a touchdown during the third quarter of the game against the Tampa Bay Buccaneers at Levi's Stadium on Dec. 11. Lachlan Cunningham/Getty Images/AFP

NFL odds are out at the best sports betting sites for player futures markets such as the most regular-season passing yardsreceiving yards, and rushing yards. Here's a look at the odds and our picks and predictions to be the NFL's leader in regular-season rushing yards in 2023.

How devalued is the running back in today's NFL? Only one rusher has eclipsed 200 yards after two weeks of play.

The race to be the NFL's rushing leader will be a competitive one.

Here are the latest odds on the running back to record the most regular-season rushing yards in 2023, using odds from our best NFL betting sites.

Most regular season rushing yards odds 2023

(odds as of Sept. 22)

Christian McCaffrey+220+225 🔥+125 ❄️+200
Derrick Henry+550 🔥+400+375 ❄️+500
Bijan Robinson+600+600+500 ❄️+600
Tony Pollard+800+800+800+800
D'Andre Swift+2100 🔥+2000+900 ❄️+2000
Austin Ekeler+5000+5000+1500 ❄️+5000
Justin Fields+6000+6600 🔥+3500 ❄️+6000
Josh Jacobs+2100+2000+3000 🔥+2000
Brian Robinson Jr.+2500+3000+4000 🔥+2500
James Conner+2000+2000+3000 🔥+2000

Most regular-season rushing yards odds analysis

Caesars has either the best or the worst odds on each of the 10 best candidates on the oddsboard. DraftKings has yet to repost its odds since Thursday Night Football.

Most regular-season rushing yards odds movement

Christian McCaffrey got a head start on the rest of the competition, getting his Week 3 action in on Thursday night. He's now up to 353 total rushing yards, and there's a 173-yard gap between he and the rest of the field.

Most regular-season rushing yards 2023: Favorite

Christian McCaffrey (+225 via BetMGM)

Run CMC is the new favorite in this category, and he's also a betting favorite in the Offensive Player of the Year odds. He currently leads the league in rushing and is averaging 5.9 yards per carry.

McCaffrey is the only rusher in the league to log more than 200 yards on the ground through two games.

Most regular-season rushing yards 2023: Contender

Derrick Henry (+550 via FanDuel)

Tennessee Titans stud running back Derrick Henry only recorded 63 yards on 15 carries in Week 1, but he followed that up with 143 yards in Week 2.

The machine of a man responded to his first injury-shortened season in 2021 with a full 16-game workload in 2022, turning that into 1,538 rushing yards. Henry is always a threat for 1,500-plus yards when healthy.

Most regular-season rushing yards 2023: Fade

Justin Fields (+6600 via BetMGM)

We're fading the +3000 odds at DraftKings here, though it's generally not wise to back Justin Fields to lead the NFL in rushing. 

The Chicago Bears quarterback recorded 1,143 yards on the ground in 2022 to finish seventh in the league. He's come out of the gates slow this season, with just three rushing yards in Week 2 against the Tampa Bay Buccaneers.

Regular-season rushing yards leaders

2022Josh Jacobs1,653
2021Jonathan Taylor1,811
2020Derrick Henry2,027
2019Derrick Henry1,540
2018Ezekiel Elliott1,434
2017Kareem Hunt1,327
2016Ezekiel Elliott1,631
2015Adrian Peterson1,485

NFL betting odds pages

Regular-season rushing yards FAQs

When will the NFL regular season rushing leader be decided?

At the conclusion of Week 18 of the regular season, the player with the most rushing yards through the season will be determined as the rushing leader.

Here are our best NFL betting sites:

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