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Colorado Buffaloes quarterback Shedeur Sanders throws the ball against the UCLA Bruins in the first half at Rose Bowl. Sanders is the favorite to go No. 1 by the 2025 NFL Draft Odds.
Colorado Buffaloes quarterback Shedeur Sanders throws the ball against the UCLA Bruins in the first half at Rose Bowl. Photo by Kirby Lee/USA TODAY Sports via Imagn.

The 2025 NFL Draft odds are available at our best NFL betting sites, with several marquee quarterbacks sitting atop the oddsboard to be the No. 1 pick.

It was widely expected for months, if not longer, that the Chicago Bears would select USC QB Caleb Williams with the No. 1 pick in the 2024 NFL Draft. When it happened, absolutely nobody was shocked. But unlike 2024, the 2025 NFL Draft is wide open.

Naturally, a pair of top QBs sit atop the oddsboard at our best sports betting sites with Colorado's Shedeur Sanders just ahead of Georgia's Carson Beck. While Sanders is the favorite to go No. 1 at this point, Beck leads the Heisman Trophy odds and Texas' Quinn Ewers isn't far behind.

After those top-notch passers, Tennessee's James Pearce Jr., Georgia's Mykel Williams, LSU's Will Campbell, and Colorado's Travis Hunter headline the non-QBs who are expected to hear their names called early in April.

As attention shifts from this past draft to next year, we look at the 2025 NFL Draft odds from our best NFL betting sites.

2025 NFL Draft odds: First overall pick

(Odds as of June 21)

PlayerDraftKings
Shedeur Sanders+380
Carson Beck+450
James Pearce Jr.+550
Quinn Ewers+950
Mykel Williams+1600
Will Campbell+2000
Travis Hunter+2000
Jalen Milroe+2000
Cameron Ward+2200
Harold Perkins Jr.+2200

Favorites to be picked first overall in the 2025 NFL Draft

Shedeur Sanders (+380 via DraftKings)

It's no surprise to see Sanders open as the favorite to be the No. 1 pick in the 2025 NFL Draft. With him and his father, Deion, jumping from Jackson State to Colorado this past season, there was plenty of buzz about the Buffaloes' investment in their football program.

Though Colorado ultimately fell flat down the stretch and missed a bowl game, Sanders was clearly not at fault. The 6-foot-2, 215-pound junior threw for 3,230 yards while completing 69.3% of his passes with 27 TDs and just three interceptions.

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Sanders was able to showcase his efficiency and accuracy throughout the season despite playing behind one of the worst offensive lines in the country. Many early mock drafts are already predicting the 22-year-old to be the top pick next April.

Carson Beck (+450 via DraftKings)

As Georgia gears up to compete as the college football championship odds favorite, Beck is receiving major Heisman hype along with being projected as a top pick in the 2025 NFL Draft. Some draftniks expected him to declare for the 2024 NFL Draft as a potential top-15 pick, but he opted to return to the Bulldogs to bolster his stock.

In his first season as Georgia's starter, Beck completed 72.4% of his passes with 24 TDs while throwing for 3,941 yards. He's been praised for his pocket presence and mechanics, along with his ability to work full-field reads.

Mykel Williams (+1600 via DraftKings)

In the modern NFL, the quarterback is king, and the NFL draft has reflected that over the last two decades. But every so often, there's a draft class lacking a clear franchise QB type. While it's too early to say if 2025 has that field general, it's shaping up to have a plethora of talented defensive prospects, making up for 2024's lack of them.

Leading the way is Georgia's Mykel Williams, who racked up 13 TFLs and nine sacks in his first two seasons with the Bulldogs. Williams has yet to breakout production-wise, but the former five-star recruit has the size (6-foot-5, 265) and athleticism the NFL covets in pass rushers.

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The only three non-QBs to be selected No. 1 in the past 11 NFL drafts have been pass-rushers (Jadeveon Clowney, Myles Garrett, Travon Walker).

2025 NFL Draft odds: Position of No. 1 overall pick

PositionFanDuel
Quarterback-165
The field+125

It's no secret that NFL franchises live and die by their quarterbacks. That's why a record-tying six QBs were taken in the first round of the 2024 NFL Draft. However, while quarterbacks have been selected first overall in eight of the last 10 draft classes, 2025 doesn't have an obvious top QB at this point.

That's what makes this market so tough to bet into before the college football season begins. Quarterbacks dominate the first overall pick, but neither Beck nor Sanders are viewed as that blue chip top choice at this point. It makes it especially difficult to feel confident in the -165 odds when the 2025 NFL Draft is shaping up to be loaded at other premium positions such as offensive tackle and edge rusher.

2025 NFL Draft odds over time

(Odds via DraftKings)

PlayerOdds on April 28Odds on June 21
Shedeur Sanders+100+380
Carson Beck+300+450
Quinn Ewers+300+950
Drew Allar+850+2500
Jalen Milroe+950+2000
Jaxson Dart+1200+2500
Cameron Ward+1500+2200
Mykel Williams+1500+1600
Patrick Payton+1800+4000
Connor Weigman+2000+4000

Past NFL draft 1st overall picks

YearPickPositionSchool
2024Caleb WilliamsQBUSC
2023Bryce YoungQBAlabama
2022Travon WalkerDEGeorgia
2021Trevor LawrenceQBClemson
2020Joe BurrowQBLSU
2019Kyler MurrayQBOklahoma
2018Baker MayfieldQBOklahoma
2017Myles GarrettDETexas A&M
2016Jared GoffQBCalifornia
2015Jameis WinstonQBFlorida State
2014Jadeveon ClowneyDESouth Carolina

How to bet on the NFL draft

Betting on the NFL draft involves understanding the various types of wagers available and conducting thorough research on prospects and team needs. Start by familiarizing yourself with the different types of bets commonly offered, such as predicting which player will be selected first overall, the order in which players will be drafted, Over/Under bets on the draft position of specific players, and prop bets related to individual player performances or team selections.

Additionally, consider factors like team needs, draft strategies, and pre-draft rumors that could impact player selections. This early in the process, it's helpful to look at mock drafts from respected draftniks to get a better idea of which players are viewed as the top talents heading into the college football season.

2025 NFL Draft FAQs

Who is the favorite to go first overall in the 2025 NFL Draft?

Colorado quarterback Shedeur Sanders (+380) is the favorite to go No. 1 in the 2025 NFL Draft. Sanders' odds imply a 20.83% chance of him being selected first overall.

Who was the first overall pick this year?

The Chicago Bears selected former USC quarterback Caleb Williams with the No. 1 overall pick of the 2024 NFL Draft, as was expected by the pre-draft odds.

When is the 2025 NFL Draft?

The first round of the 2025 NFL Draft will be held on Thursday, April 24, and the event concludes on Saturday, April 26.

Where is the 2025 NFL Draft?

The 2025 NFL Draft will be held  at Lambeau Field in Green Bay, Wisc.

Here are our best NFL betting sites:

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* Bonuses not applicable in Ontario.

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