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Head coach Andy Reid of the Kansas City Chiefs prepares for a preseason game as we offer a look at the NFL odds and lines for every game.
Head coach Andy Reid of the Kansas City Chiefs prepares for a preseason game against the Arizona Cardinals at State Farm Stadium on August 19, 2023 in Glendale, Arizona. Photo by Norm Hall/Getty Images via AFP.

The football season is set to get underway and bettors have access to a wide array of NFL odds from Week 1 through Week 18 via our best NFL betting sites.

Our best sports betting apps were quick to help satiate the appetites of NFL bettors by releasing odds for every game on the 2023 NFL calendar shortly after the schedule was released. An edge can be gained by targeting some of these early lines from DraftKings, but more importantly, looking back at the opening projections of oddsmakers can help remove the threat of recency bias and perception once games start being played.

Use this page to help with your analysis of the weekly NFL odds and lines by referencing the opening numbers from our best sports betting sites.

NFL opening odds & betting lines 2023

Odds and lines
Week 1
Week 2
Week 3
Week 4

Opening lines for Week 3

Week 3 features several lopsided matchups based on these early odds with six games facing a spread of 6 or more points. The Dallas Cowboys and Philadelphia Eagles are the two heavy road favorites against opponents expected to be among the teams with the worst NFL regular-season record in 2023.

Giants vs. 49ers (-4.5)Thursday, Sept. 218:15 p.m. ETPRIME VIDEO
Titans vs. Browns (-4.5)Sunday, Sept. 241 p.m. ETCBS
Falcons vs. Lions (-5)Sunday, Sept. 241 p.m. ETFOX
Saints vs. Packers (-1)Sunday, Sept. 241 p.m. ETFOX
Broncos vs. Dolphins (-3.5)Sunday, Sept. 241 p.m. ETCBS
Chargers (-1.5) vs. VikingsSunday, Sept. 241 p.m. ETFOX
Patriots vs. Jets (-3.5)Sunday, Sept. 241 p.m. ETCBS
Bills (-4.5) vs. CommandersSunday, Sept. 241 p.m. ETCBS
Texans vs. Jaguars (-7)Sunday, Sept. 241 p.m. ETFOX
Colts vs. Ravens (-7)Sunday, Sept. 241 p.m. ETCBS
Panthers vs. Seahawks (-4)Sunday, Sept. 244:05 p.m. ETCBS
Bears vs. Chiefs (-9.5)Sunday, Sept. 244:25 p.m. ETFOX
Cowboys (-6.5) vs. CardinalsSunday, Sept. 244:25 p.m. ETFOX
Steelers vs. Raiders (-1.5)Sunday, Sept. 248:20 p.m. ETNBC
Eagles (-6) vs. BuccaneersMonday, Sept. 257:15 p.m. ETABC
Rams vs. Bengals (-7)Monday, Sept. 258:15 p.m. ETESPN

Opening lines for Week 4

One of the most surprising opening spreads to this point has the Chiefs as meager 1-point favorites on the road against the Jets on Sunday Night Football. Early struggles by Rodgers with his new team could swing this line drastically by the time Week 4 comes around so the Chiefs are interesting at this low number.

The Jacksonville Jaguars are moderate favorites in a neutral-site game against the Atlanta Falcons in London.

Lions (-1.5) vs. PackersThursday, Sept. 288:15 p.m. ETESPN+
Falcons vs. Jaguars (-4)Sunday, Oct. 19:30 a.m. ET (London)CBS
Dolphins vs. Bills (-3.5)Sunday, Oct. 11 p.m. ETCBS
Broncos (-1.5) vs. BearsSunday, Oct. 11 p.m. ETCBS
Ravens vs. Browns (-1)Sunday, Oct. 11 p.m. ETFOX
Bengals (-4.5) vs. TitansSunday, Oct. 11 p.m. ETFOX
Rams (-1) vs. ColtsSunday, Oct. 11 p.m. ETFOX
Buccaneers vs. Saints (-3.5)Sunday, Oct. 11 p.m. ETFOX
Commanders vs. Eagles (-7)Sunday, Oct. 11 p.m. ETFOX
Vikings (-1.5) vs. PanthersSunday, Oct. 11 p.m. ETFOX
Steelers (-3.5) vs. TexansSunday, Oct. 11 p.m. ETCBS
Raiders vs. Chargers (-4.5)Sunday, Oct. 14:05 p.m. ETCBS
Patriots vs. Cowboys (-3.5)Sunday, Oct. 14:25 p.m. ETFOX
Cardinals vs. 49ers (-9.5)Sunday, Oct. 14:25 p.m. ETFOX
Chiefs (-1) vs. JetsSunday, Oct. 18:20 p.m. ETNBC
Seahawks vs. Giants (-1)Monday, Oct. 28:15 p.m. ETESPN

Opening lines for Week 5

The Jaguars will remain in London for consecutive weeks in a de facto home game against the Bills but are 3.5-point underdogs despite not needing to travel. A convincing win over the Falcons could tilt this line in their favor.

Week 5 sees four teams on a bye for the first time in the 2023 season.

Bears vs. Commanders (-1.5)Thursday, Oct. 58:15 p.m. ETPRIME VIDEO
Jaguars vs. Bills (-3.5)Sunday, Oct. 89:30 a.m. ET (London)NFL NETWORK
Texans vs. Falcons (-3)Sunday, Oct. 81 p.m. ETFOX
Panthers vs. Lions (-5)Sunday, Oct. 81 p.m. ETFOX
Titans vs. Colts (-1)Sunday, Oct. 81 p.m. ETCBS
Giants vs. Dolphins (-4.5)Sunday, Oct. 81 p.m. ETFOX
Saints vs. Patriots (-3)Sunday, Oct. 81 p.m. ETCBS
Ravens (-1) vs. SteelersSunday, Oct. 81 p.m. ETCBS
Eagles (-4.5) vs. RamsSunday, Oct. 84:05 p.m. ETFOX
Bengals (-7.5) vs. CardinalsSunday, Oct. 84:05 p.m. ETFOX
Jets (-1) vs. BroncosSunday, Oct. 84:25 p.m. ETCBS
Chiefs (-4) vs. VikingsSunday, Oct. 84:25 p.m. ETCBS
Cowboys vs. 49ers (-2)Sunday, Oct. 88:20 p.m. ETNBC
Packers vs. Raiders (-1.5)Monday, Oct. 98:15 p.m. ETESPN

Teams on bye: Browns, Chargers, Seahawks, Buccaneers

Opening lines for Week 6

We have more lopsided spreads in Week 6 with three home teams favored by a touchdown and another favored by 6.5 points. Interestingly, two of those games are on primetime, so we'll see if public betting action helps to push the number even higher for the favorites, especially for the Chiefs on Thursday Night Football.

Broncos vs. Chiefs (-7)Thursday, Oct. 128:15 p.m. ETPRIME VIDEO
Ravens (-5.5) vs. TitansSunday, Oct. 159:30 a.m. ET (London)NFL NETWORK
Commanders vs. Falcons (-1)Sunday, Oct. 151 p.m. ETCBS
Vikings (-1) vs. BearsSunday, Oct. 151 p.m. ETFOX
Seahawks vs. Bengals (-4.5)Sunday, Oct. 151 p.m. ETCBS
49ers (-1) vs. BrownsSunday, Oct. 151 p.m. ETFOX
Panthers vs. Dolphins (-7)Sunday, Oct. 151 p.m. ETCBS
Lions (-3.5) vs. BuccaneersSunday, Oct. 151 p.m. ETFOX
Colts vs. Jaguars (-6.5)Sunday, Oct. 151 p.m. ETCBS
Saints (-2.5) vs. TexansSunday, Oct. 151 p.m. ETFOX
Patriots (-1.5) vs. RaidersSunday, Oct. 154:05 p.m. ETCBS
Cardinals vs. Rams (-4)Sunday, Oct. 154:25 p.m. ETFOX
Eagles vs. Jets (-1)Sunday, Oct. 154:25 p.m. ETFOX
Giants vs. Bills (-7)Sunday, Oct. 158:20 p.m. ETNBC
Cowboys vs. Chargers (-1)Monday, Oct. 168:15 p.m. ETESPN

Teams on bye: Packers, Steelers

Opening lines for Week 7

Two of the three primetime games for Week 7 have a spread of just 1 point with the other also within a field goal. The most surprising of those lines has the Eagles as modest 2.5-point home favorites against the Miami Dolphins.

Jaguars (-1) vs. SaintsThursday, Oct. 198:15 p.m. ETPRIME VIDEO
Raiders vs. Bears (-1)Sunday, Oct. 221 p.m. ETFOX
Browns (-3) vs. ColtsSunday, Oct. 221 p.m. ETCBS
Bills (-2.5) vs. PatriotsSunday, Oct. 221 p.m. ETCBS
Commanders vs. Giants (-2.5)Sunday, Oct. 221 p.m. ETCBS
Falcons (-1) vs. BuccaneersSunday, Oct. 221 p.m. ETFOX
Lions vs. Ravens (-2)Sunday, Oct. 221 p.m. ETFOX
Steelers (-1) vs. RamsSunday, Oct. 224:05 p.m. ETFOX
Cardinals vs. Seahawks (-7)Sunday, Oct. 224:05 p.m. ETFOX
Packers vs. Broncos (-3.5)Sunday, Oct. 224:25 p.m. ETCBS
Chargers vs. Chiefs (-5.5)Sunday, Oct. 224:25 p.m. ETCBS
Dolphins vs. Eagles (-2.5)Sunday, Oct. 228:20 p.m. ETNBC
49ers (-1) vs. VikingsMonday, Oct. 238:15 p.m. ETESPN

Teams on bye: Bengals, Cowboys, Titans, Jets, Panthers, Texans

Opening lines for Week 8

Thursday of Week 8 may be a good night to find alternative plans with the Bills comfortable 10-point home favorites against the Buccaneers. This is our first double-digit spread of the season and it's difficult to envision Bucs' QB Baker Mayfield doing enough in the first seven weeks of the season to lower this number.

The Los Angeles Chargers and Lions are also favored by more than a field goal on primetime in Week 8.

Buccaneers vs. Bills (-10)Thursday, Oct. 268:15 p.m. ETPRIME VIDEO
Rams vs. Cowboys (-6)Sunday, Oct 291 p.m. ETFOX
Vikings (-1) vs. PackersSunday, Oct 291 p.m. ETFOX
Falcons vs. Titans (-1)Sunday, Oct 291 p.m. ETCBS
Saints (-1.5) vs. ColtsSunday, Oct 291 p.m. ETFOX
Patriots vs. Dolphins (-4)Sunday, Oct 291 p.m. ETCBS
Jets (-1.5) vs. GiantsSunday, Oct 291 p.m. ETCBS
Jaguars vs. Steelers (-1)Sunday, Oct 291 p.m. ETCBS
Eagles (-4) vs. CommandersSunday, Oct 291 p.m. ETFOX
Texans vs. Panthers (-3)Sunday, Oct 291 p.m. ETFOX
Browns vs. Seahawks (-1.5)Sunday, Oct 294:05 p.m. ETFOX
Chiefs (-3.5) vs. BroncosSunday, Oct 294:25 p.m. ETCBS
Ravens (-5.5) vs. CardinalsSunday, Oct 294:25 p.m. ETCBS
Bengals vs. 49ers (-1)Sunday, Oct 294:25 p.m. ETCBS
Bears vs. Chargers (-5.5)Sunday, Oct 298:20 p.m. ETNBC
Raiders vs. Lions (-3.5)Monday, Oct. 308:15 p.m. ETESPN

Opening lines for Week 9

One of the best Sunday Night Football matchups of the season takes place in Week 9 with the Cincinnati Bengals set as 1-point home favorites against the Buffalo Bills. That'll be followed by a Monday night contest between the Chargers and Jets with Gang Green once again an early home favorite with Rodgers at the helm.

Titans vs. Steelers (-4)Thursday, Nov. 28:15 p.m. ETPRIME VIDEO
Dolphins vs. Chiefs (-5.5)Sunday, Nov. 59:30 a.m. ET (Germany)NFL NETWORK
Vikings (-1) vs. FalconsSunday, Nov. 51 p.m. ETFOX
Cardinals vs. Browns (-7)Sunday, Nov. 51 p.m. ETCBS
Rams vs. Packers (-1.5)Sunday, Nov. 51 p.m. ETFOX
Commanders vs. Patriots (-3.5)Sunday, Nov. 51 p.m. ETFOX
Bears vs. Saints (-2)Sunday, Nov. 51 p.m. ETCBS
Seahawks vs. Ravens (-2.5)Sunday, Nov. 51 p.m. ETCBS
Buccaneers vs. Texans (-1)Sunday, Nov. 51 p.m. ETCBS
Colts vs. Panthers (-2.5)Sunday, Nov. 54:05 p.m. ETCBS
Giants vs. Raiders (-1.5)Sunday, Nov. 54:25 p.m. ETFOX
Cowboys vs. Eagles (-3)Sunday, Nov. 54:25 p.m. ETFOX
Bills vs. Bengals (-1)Sunday, Nov. 58:20 p.m. ETNBC
Chargers vs. Jets (-2)Monday, Nov. 68:15 p.m. ETESPN

Teams on bye: Broncos, Lions, 49ers, Jaguars

Opening lines for Week 10

Week 10 starts with what's expected to be an exciting quarterback battle between No. 1 pick Bryce Young and the Carolina Panthers against NFL MVP hopeful Justin Fields and the Chicago Bears. Fellow top rookie QB C.J. Stroud faces a stiffer test when his Texans visit the Bengals as 9.5-point underdogs on the early line.

Panthers vs. Bears (-2)Thursday, Nov. 98:15 p.m. ETPRIME VIDEO
Colts vs. Patriots (-5)Sunday, Nov. 129:30 a.m. ET (Germany)NFL NETWORK
Texans vs. Bengals (-9.5)Sunday, Nov. 121 p.m. ETCBS
Saints vs. Vikings (-2.5)Sunday, Nov. 121 p.m. ETFOX
Packers vs. Steelers (-3)Sunday, Nov. 121 p.m. ETCBS
Titans (-1) vs. BuccaneersSunday, Nov. 121 p.m. ETCBS
49ers (-1) vs. JaguarsSunday, Nov. 121 p.m. ETFOX
Browns vs. Ravens (-3)Sunday, Nov. 121 p.m. ETFOX
Falcons (-1.5) vs. CardinalsSunday, Nov. 124:05 p.m. ETCBS
Lions vs. Chargers (-2.5)Sunday, Nov. 124:05 p.m. ETCBS
Giants vs. Cowboys (-4.5)Sunday, Nov. 124:25 p.m. ETFOX
Commanders vs. Seahawks (-3.5)Sunday, Nov. 124:25 p.m. ETFOX
Jets (-2.5) vs. RaidersSunday, Nov. 128:20 p.m. ETNBC
Broncos vs. Bills (-6)Monday, Nov. 138:15 p.m. ETESPN

Teams on bye: Chiefs, Rams, Dolphins, Eagles

Opening lines for Week 11

Week 11 is bracketed by two stellar matchups for Thursday Night Football and Monday Night Football. Lamar Jackson and the Baltimore Ravens will first host Joe Burrow and the Bengals as 1-point underdogs before a Super Bowl rematch between the Chiefs and Eagles in Kansas City. A 3-point spread favors the home team. 

Bengals (-1) vs. RavensThursday, Nov. 168:15 p.m. ETPRIME VIDEO
Steelers vs. Browns (-1.5)Sunday, Nov. 191 p.m. ETCBS
Bears vs. Lions (-5)Sunday, Nov. 191 p.m. ETFOX
Chargers (-2.5) vs. PackersSunday, Nov. 191 p.m. ETFOX
Raiders vs. Dolphins (-5.5)Sunday, Nov. 191 p.m. ETCBS
Giants (-1.5) vs. CommandersSunday, Nov. 191 p.m. ETFOX
Cowboys (-3.5) vs. PanthersSunday, Nov. 191 p.m. ETFOX
Titans vs. Jaguars (-4.5)Sunday, Nov. 191 p.m. ETCBS
Cardinals vs. Texans (-1.5)Sunday, Nov. 191 p.m. ETCBS
Buccaneers vs. 49ers (-7.5)Sunday, Nov. 194:05 p.m. ETFOX
Jets vs. Bills (-3.5)Sunday, Nov. 194:25 p.m. ETCBS
Seahawks (-1.5) vs. RamsSunday, Nov. 194:25 p.m. ETCBS
Vikings vs. Broncos (-2)Sunday, Nov. 198:20 p.m. ETNBC
Eagles vs. Chiefs (-3)Monday, Nov. 208:15 p.m. ETESPN/ABC

Teams on bye: Falcons, Colts, Patriots, Saints

Opening lines for Week 12

Tables are turned in all-NFC North matchup opening the Thanksgiving Day slate. The Lions are 4-point home favorites over the Jordan Love-led Green Bay Packers. Black Friday features an all-AFC-East battle between the Dolphins and Jets with New York laying 2.5 points at home. Sunday's slate has eight games with a spread within a field goal.

Packers vs. Lions (-4)Thursday, Nov. 2312:30 p.m. ETFOX
Commanders vs. Cowboys (-5.5)Thursday, Nov. 234:30 p.m. ETCBS
49ers (-1.5) vs. SeahawksThursday, Nov. 238:20 p.m. ETNBC
Dolphins vs. Jets (-2.5)Friday, Nov. 243 p.m. ETPRIME VIDEO
Saints (-1) vs. FalconsSunday, Nov. 261 p.m. ETFOX
Steelers vs. Bengals (-4.5)Sunday, Nov. 261 p.m. ETCBS
Panthers vs. Titans (-1)Sunday, Nov. 261 p.m. ETFOX
Buccaneers vs. Colts (-1)Sunday, Nov. 261 p.m. ETCBS
Patriots vs. Giants (-1.5)Sunday, Nov. 261 p.m. ETFOX
Jaguars (-4.5) vs. TexansSunday, Nov. 261 p.m. ETCBS
Browns vs. Broncos (-1)Sunday, Nov. 261 p.m. ETFOX
Rams (-2) vs. CardinalsSunday, Nov. 264:05 p.m. ETFOX
Chiefs (-5) vs. RaidersSunday, Nov. 264:25 p.m. ETCBS
Bills vs. Eagles (-1.5)Sunday, Nov. 264:25 p.m. ETCBS
Ravens vs. Chargers (-2)Sunday, Nov. 268:20 p.m. ETNBC
Bears vs. Vikings (-3.5)Monday, Nov. 278:15 p.m. ETESPN

Opening lines for Week 13

The San Francisco 49ers face the Eagles in an NFC Championship Game rematch in Week 13. The Eagles are modest 2.5-point favorites on the early line. Still, it's the Chiefs who'll be featured on Sunday Night Football while laying 5.5 points against the Packers on the opening line.

Seahawks vs. Cowboys (-3.5)Thursday, Nov. 308:15 p.m. ETPRIME VIDEO
Colts vs. Titans (-2.5)Sunday, Dec. 31 p.m. ETCBS
Chargers (-1.5) vs. PatriotsSunday, Dec. 31 p.m. ETCBS
Lions (-1.5) vs. SaintsSunday, Dec. 31 p.m. ETFOX
Falcons vs. Jets (-6.5)Sunday, Dec. 31 p.m. ETFOX
Cardinals vs. Steelers (-6.5)Sunday, Dec. 31 p.m. ETCBS
Panthers (-1) vs. BuccaneersSunday, Dec. 31 p.m. ETCBS
Dolphins (-3.5) vs. CommandersSunday, Dec. 31 p.m. ETFOX
Broncos (-4) vs. TexansSunday, Dec. 34:05 p.m. ETCBS
Browns (-1) vs. RamsSunday, Dec. 34:25 p.m. ETFOX
49ers vs. Eagles (-2.5)Sunday, Dec. 34:25 p.m. ETFOX
Chiefs (-5.5) vs. PackersSunday, Dec. 38:20 p.m. ETNBC
Bengals (-1) vs. JaguarsMonday, Dec. 48:15 p.m. ETESPN

Teams on bye: Bills, Bears, Raiders, Vikings, Giants, Ravens

Opening lines for Week 14

The Bills and Chiefs play their now-annual pre-playoff contest in mid-December but it's only part of Sunday's late-afternoon slate. The opening spread has the Chiefs laying 3.5 points at home. Sunday Night Football has the Dallas Cowboys as 1-point home favorites against the rival Eagles.

Patriots vs. Steelers (-1)Thursday, Dec. 78:15 p.m. ETPRIME VIDEO
Buccaneers vs. Falcons (-2.5)Sunday, Dec. 101 p.m. ETCBS
Lions (-1.5) vs. BearsSunday, Dec. 101 p.m. ETFOX
Colts vs. Bengals (-9)Sunday, Dec. 101 p.m. ETCBS
Jaguars vs. Browns (-1)Sunday, Dec. 101 p.m. ETCBS
Panthers vs. Saints (-2.5)Sunday, Dec. 101 p.m. ETFOX
Texans vs. Jets (-8.5)Sunday, Dec. 101 p.m. ETCBS
Rams vs. Ravens (-5)Sunday, Dec. 101 p.m. ETFOX
Vikings vs. Raiders (-1.5)Sunday, Dec. 104:05 p.m. ETFOX
Seahawks vs. 49ers (-3.5)Sunday, Dec. 104:05 p.m. ETFOX
Bills vs. Chiefs (-3.5)Sunday, Dec. 104:25 p.m. ETCBS
Broncos vs. Chargers (-3)Sunday, Dec. 104:25 p.m. ETCBS
Eagles vs. Cowboys (-1)Sunday, Dec. 108:20 p.m. ETNBC
Titans vs. Dolphins (-7.5)Monday, Dec. 118:15 p.m. ETESPN
Packers vs. Giants (-2.5)Monday, Dec. 118:15 p.m. ETABC

Teams on bye: Cardinals, Commanders

Opening lines for Week 15

As the playoff race heats up, 10 games in Week 15 have an opening spread within a touchdown. The standings for the final quarter of the season and what's at stake for each team could cause big fluctuations in these early lines.

Chargers (-1.5) vs. RaidersThursday, Dec. 148:15 p.m. ETPRIME VIDEO
Vikings vs. Bengals (-5)Sunday, Dec. 17TBD
Bears vs. Browns (-3.5)Sunday, Dec. 17TBD
Broncos vs. Lions (-2)Sunday, Dec. 17TBD
Steelers (-2.5) vs. ColtsSunday, Dec. 17TBD
Falcons vs. Panthers (-1)Sunday, Dec. 17TBD
Buccaneers vs. Packers (-3.5)Sunday, Dec. 171 p.m. ETFOX
Texans vs. Titans (-3)Sunday, Dec. 171 p.m. ETCBS
Jets vs. Dolphins (-1.5)Sunday, Dec. 171 p.m. ETCBS
Giants vs. Saints (-1)Sunday, Dec. 171 p.m. ETFOX
Commanders vs. Rams (-1)Sunday, Dec. 174:05 p.m. ETCBS
49ers (-6.5) vs. CardinalsSunday, Dec. 174:05 p.m. ETCBS
Cowboys vs. Bills (-4)Sunday, Dec. 174:25 p.m. ETFOX
Eagles (-2) vs. SeahawksSunday, Dec. 174:25 p.m. ETFOX
Ravens vs. Jaguars (-1)Sunday, Dec. 178:20 p.m. ETNBC
Chiefs (-3.5) vs. PatriotsMonday, Dec. 188:15 p.m. ETESPN

Opening lines for Week 16

Tight spreads remain a theme for Week 16 with another 10 matchups projected to be played within a field goal. Another theme continues with Sunday Night Football featuring one of the most lopsided matchups of the week by the early odds.

Saints vs. Rams (-1)Thursday, Dec. 218:15 p.m. ETPRIME VIDEO
Bengals (-2.5) vs. SteelersSaturday,. Dec. 234:30 p.m. ETNBC
Bills (-1) vs. ChargersSaturday,. Dec. 238 p.m. ETPeacock
Colts vs. Falcons (-2.5)Sunday, Dec. 241 p.m. ETFOX
Seahawks (-2) vs. TitansSunday, Dec. 241 p.m. ETCBS
Lions vs. Vikings (-1)Sunday, Dec. 241 p.m. ETFOX
Commanders vs. Jets (-5.5)Sunday, Dec. 241 p.m. ETCBS
Packers (-1) vs. PanthersSunday, Dec. 241 p.m. ETFOX
Browns (-4) vs. TexansSunday, Dec. 241 p.m. ETCBS
Jaguars (-3.5) vs. BuccaneersSunday, Dec. 244:05 p.m. ETCBS
Cardinals vs. Bears (-4.5)Sunday, Dec. 244:25 p.m. ETFOX
Cowboys vs. Dolphins (-1.5)Sunday, Dec. 244:25 p.m. ETFOX
Patriots vs. Broncos (-1.5)Sunday, Dec. 248:15 p.m. ETNFL NETWORK
Raiders vs. Chiefs (-8.5)Monday, Dec. 251 p.m. ETCBS
Giants vs. Eagles (-7)Monday, Dec. 254:30 p.m. ETFOX
Ravens vs. 49ers (-3)Monday, Dec. 258:15 p.m. ETABC

Opening lines for Week 17

Our second 10-point spread of the season has the Eagles laying exactly that number at home against the lowly Arizona Cardinals. It's possible neither team will have anything to play for in the penultimate game of the season, but Philly may be just as big of a favorite in a battle of backups. A more exciting matchup has the Chiefs and Bengals likely battling for playoff seeding in the AFC on Sunday evening. K.C. is laying 3.5 points on the early line.

Jets (-1) vs. BrownsThursday, Dec. 288:15 p.m. ETPRIME VIDEO
Lions vs. Cowboys (-2.5)Saturday, Dec. 308:15 p.m. ETESPN/ABC
Patriots vs. Bills (-5.5)Sunday, Dec. 311 p.m. ETCBS
Falcons vs. Bears (-2)Sunday, Dec. 311 p.m. ETCBS
Raiders (-2) vs. ColtsSunday, Dec. 311 p.m. ETCBS
Rams vs. Giants (-3)Sunday, Dec. 311 p.m. ETFOX
Cardinals vs. Eagles (-10)Sunday, Dec. 311 p.m. ETFOX
Saints (-1.5) vs. BuccaneersSunday, Dec. 311 p.m. ETFOX
49ers (-3) vs. CommandersSunday, Dec. 311 p.m. ETFOX
Panthers vs. Jaguars (-5)Sunday, Dec. 311 p.m. ETCBS
Dolphins vs. Ravens (-1)Sunday, Dec. 311 p.m. ETCBS
Titans (-1) vs. TexansSunday, Dec. 311 p.m. ETFOX
Steelers vs. Seahawks (-2)Sunday, Dec. 314:05 p.m. ETFOX
Chargers vs. Broncos (-1)Sunday, Dec. 314:25 p.m. ETCBS
Bengals vs. Chiefs (-3.5)Sunday, Dec. 314:25 p.m. ETCBS
Packers vs. Vikings (-2.5)Sunday, Dec. 318:20 p.m. ETNBC

Opening lines for Week 18

Betting on Week 18 before the season even begins is a true test of prognostication. Studying the NFL playoff odds can help you gauge what may be at stake for each team.

Browns vs. Bengals (-4)Sunday, Jan. 7TBD
Vikings vs. Lions (-2.5)Sunday, Jan. 7TBD
Bears vs. Packers (-2)Sunday, Jan. 7TBD
Jaguars (-2.5) vs. TitansSunday, Jan. 7TBD
Texans vs. Colts (-1.5)Sunday, Jan. 7TBD
Broncos (-1) vs. RaidersSunday, Jan. 7TBD
Bills vs. Dolphins (-1.5)Sunday, Jan. 7TBD
Jets (-1) vs. PatriotsSunday, Jan. 7TBD
Falcons vs. Saints (-2.5)Sunday, Jan. 7TBD
Eagles (-2.5) vs. GiantsSunday, Jan. 7TBD
Seahawks (-4.5) vs. CardinalsSunday, Jan. 7TBD
Chiefs (-2) vs. ChargersSunday, Jan. 7TBD
Rams vs. 49ers (-6)Sunday, Jan. 7TBD
Cowboys (-3) vs. CommandersSunday, Jan. 7TBD
Buccaneers vs. Panthers (-2.5)Sunday, Jan. 7TBD
Steelers vs. Ravens (-3.5)Sunday, Jan. 7TBD

Completed weeks

Opening lines for Week 1

The Super Bowl champion Kansas City Chiefs get the ball rolling on the 2023 NFL season with a home matchup against the Detroit Lions, who suddenly find themselves beginning a season with playoff aspirations expectations in a new-look NFC North. To little surprise, the Chiefs are heavy home favorites, but this matchup will serve as an excellent litmus test for the Lions heading into Week 2 and beyond.

The Buffalo Bills will get the first taste of an Aaron Rodgers-led New York Jets squad under the bright lights of Monday Night Football as short road favorites in the rivalry matchup.

Lions vs. Chiefs (-6.5)Thursday, Sept. 78:20 p.m. ETNBC
Panthers vs. Falcons (-2.5)Sunday, Sept. 101 p.m. ETFOX
Bengals (-2.5) vs. BrownsSunday, Sept. 101 p.m. ETCBS
Jaguars (-3.5) vs. ColtsSunday, Sept. 101 p.m. ETFOX
Buccaneers vs. Vikings (-7)Sunday, Sept. 101 p.m. ETCBS
Titans vs. Saints (-3.5)Sunday, Sept. 101 p.m. ETCBS
49ers (-3) vs. SteelersSunday, Sept. 101 p.m. ETFOX
Cardinals vs. Commanders (-5.5)Sunday, Sept. 101 p.m. ETFOX
Texans vs. Ravens (-9)Sunday, Sept. 101 p.m. ETCBS
Packers vs. Bears (-2.5)Sunday, Sept. 104:25 p.m. ETFOX
Raiders vs. Broncos (-3.5)Sunday, Sept. 104:25 p.m. ETCBS
Eagles (-4.5) vs. PatriotsSunday, Sept. 104:25 p.m. ETCBS
Dolphins vs. Chargers (-2.5)Sunday, Sept. 104:25 p.m. ETCBS
Rams vs. Seahawks (-5.5)Sunday, Sept. 104:25 p.m. ETFOX
Cowboys (-2.5) vs. GiantsSunday, Sept. 108:20 p.m. ETNBC
Bills (-2.5) vs. JetsMonday, Sept. 118:15 p.m. ETESPN/ABC

Opening lines for Week 2

One of the more interesting matchups of Week 2 pits the AFC South rival Indianapolis Colts and Houston Texans against each other. Be careful of overreacting to Week 1 results for either team, as both sides are expected to roll out their star rookie quarterback in head-to-head competition for the first time. A new era for the Tampa Bay Buccaneers sees them as early-season home underdogs against the playoff-hopeful Chicago Bears.

Vikings vs. Eagles (-5.5)Thursday, Sept. 148:15 p.m. ETPRIME VIDEO
Packers (-1) vs. FalconsSunday, Sept. 171 p.m. ETFOX
Raiders vs. Bills (-7.5)Sunday, Sept. 171 p.m. ETCBS
Ravens vs. Bengals (-3.5)Sunday, Sept. 171 p.m. ETCBS
Seahawks vs. Lions (-2)Sunday, Sept. 171 p.m. ETFOX
Chargers (-3.5) vs. TitansSunday, Sept. 171 p.m. ETCBS
Bears (-1.5) vs. BuccaneersSunday, Sept. 171 p.m. ETFOX
Chiefs (-3) vs. JaguarsSunday, Sept. 171 p.m. ETCBS
Colts vs. Texans (-1)Sunday, Sept. 171 p.m. ETFOX
49ers (-3) vs. RamsSunday, Sept. 174:05 p.m. ETFOX
Giants (-4) vs. CardinalsSunday, Sept. 174:05 p.m. ETFOX
Jets vs. Cowboys (-1)Sunday, Sept. 174:25 p.m. ETCBS
Commanders vs. Broncos (-3.5)Sunday, Sept. 174:25 p.m. ETCBS
Dolphins (-1) vs. PatriotsSunday, Sept. 178:20 p.m. ETNBC
Saints vs. Panthers (-1)Monday, Sept. 187:15 p.m. ETESPN
Browns vs. Steelers (-1)Monday, Sept. 188:15 p.m. ETABC

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