NFL Week 11 Odds & Betting Lines: Spread, Moneyline, Over/Under for All 14 Games

The NFL odds for Week 11 are out, and it'll be the second-straight 14-game week. Our best NFL betting sites will be active throughout the week, and action finally gets underway in a few hours.

• The Thursday Night Football odds favorite Philadelphia Eagles (-4) covered against the Washington Commander, 26-18, as the Under 49 cashed
• The Sunday Night Football odds were saved when the Cincinnati Bengals visiting the Los Angeles Chargers was flexed into the limelight (8:20 p.m. ET, NBC/Peacock)
• The Monday Night Football odds opened with the visiting Houston Texans lined as nearly full-touchdown favorites over the Dallas Cowboys (8:15 p.m. ET, ESPN/ABC)
• The New York Giants, Arizona Cardinals, Tampa Bay Buccaneers, and Carolina Panthers are on a bye

NFL Week 11 odds and lines

There's an edge to betting NFL odds early and trying to beat the closing line in NFL markets. The closer you wait to Sunday to make your NFL picks, the more difficult it becomes to identify advantages and secure the best number on a side or total.

That's why it's important to start monitoring the NFL opening odds each week as soon as possible. A proactive approach will aid your long-term success.

Best NFL Week 11 spreads

(Odds via DraftKings)

• Divisional rivalry games remaining: Commanders vs. Eagles (TNF); Ravens vs. Steelers; Packers vs. Bears; Seahawks vs. 49ers
• Half of the Week 11 games have opened with the home squad listed as the underdog
• The Bills and Broncos have flipped to favorites as of Monday morning
• Half the slate is lined with a spread of three or fewer points to open, and remain in that range as of Monday
• Super Bowl odds contenders in the Kansas City Chiefs and Buffalo Bills square off in the most significant game on the slate
• ATS leaders heading into Week 11: Commanders (7-2-1), Steelers (7-2), Lions (7-2), Colts (7-3), Cardinals (7-3), Broncos (7-3)
• ATS losers heading into Week 11: Titans (1-8), Cowboys (2-7), Dolphins (2-6), Seahawks (2-6-1)

Best NFL Week 11 moneylines

(Odds via FanDuel)

Here are some of the major questions we asked going into Week 9, and the answers ahead of Week 10: 

• How will the New Orleans Saints look with a new head coach after Dennis Allen was relieved of his duties ahead of Week 10?
• They pulled off a large divisional victory over the Falcons and pulled away in early betting, but during the week things they have become a very small underdog
• Joe Flacco fell short as Anthony Richardson's replacement in Week 9 for the Colts, but will he step it up in Week 10?
• The Colts again did not look fantastic, failing to keep pace with the Bills; as of Thursday, Coach Steichen had reverted to Richardson as QB
• How will the Dallas Cowboys look in Cooper Rush's first start for the injured Dak Prescott?
• Not competitive, although like the Colts against the Bills, the Cowboys faced a tall task against the Eagles. The Texans won't be much easier.

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Best NFL Week 11 Over/Unders

(Odds via bet365)

44 (110/-11

• Over leaders heading into Week 11: Ravens (9-1); Panthers (7-3), Bucs (7-3), Commanders (7-3), Bengals (7-3)
• Under leaders heading into Week 11: Texans (2-8), Chargers (2-7), Giants (3-7), Bears (3-6), Vikings (3-6), Browns (3-6)
• Opening market highs: The Jaguars vs. Lions is the only game lined at more than 50 points to open while sitting at 50.5
• The Jags were forced to switch to Mac Jones at QB after Trevor Lawrence's injury was revealed and Jags-Lions has fallen to 46.5 in turn
• Thursday Night Football's Commanders-Eagles (48.5) is the high mark for the week
• Opening market lows: It's a rare week, but no games are lined with fewer than 40 points at open: the Vikings vs. Titans opening of 41.5 is the low watermark for the week.
• That's now the lone game under 40 points, falling to 39.5 in early betting as the Titans remain inept offensively and the Vikings fell flat on Sunday

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NFL betting odds pages

Here are our best NFL betting sites:

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• DraftKings Promo Code | Read our DraftKings Review

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