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Los Angeles Rams safety Jaylen McCollough celebrates with teammates, including Ahkello Witherspoon and Charles Woods following an interception. Photo by: Joe Nicholson-Imagn Images

The NFL odds for Week 11 are out, and it'll be the second-straight 14-game week. Our best NFL betting sites will be active throughout the week, and action finally gets underway in a few hours.

  • The Thursday Night Football odds favorite Philadelphia Eagles (-4) covered against the Washington Commander, 26-18, as the Under 49 cashed
  • The Sunday Night Football odds were saved when the Cincinnati Bengals visiting the Los Angeles Chargers was flexed into the limelight (8:20 p.m. ET, NBC/Peacock)
  • The Monday Night Football odds opened with the visiting Houston Texans lined as nearly full-touchdown favorites over the Dallas Cowboys (8:15 p.m. ET, ESPN/ABC)
  • The New York Giants, Arizona Cardinals, Tampa Bay Buccaneers, and Carolina Panthers are on a bye

NFL Week 11 odds and lines

There's an edge to betting NFL odds early and trying to beat the closing line in NFL markets. The closer you wait to Sunday to make your NFL picks, the more difficult it becomes to identify advantages and secure the best number on a side or total.

That's why it's important to start monitoring the NFL opening odds each week as soon as possible. A proactive approach will aid your long-term success.

Best NFL Week 11 spreads

(Odds via DraftKings)

GameNov. 14Nov. 11Opening spread (Nov. 6)
Jaguars vs. LionsLions -13Lions -13Lions -10
Ravens vs. SteelersSteelers +3Steelers +3Steelers +3
Rams vs. PatriotsPatriots +4.5Patriots +5.5Patriots +6
Packers vs. BearsBears +5.5Bears +6.5Bears +2.5
Colts vs. JetsJets -4Jets -3Jets -4.5
Vikings vs. TitansTitans +6Titans +6.5Titans +6
Browns vs. SaintsSaints -1Saints -2.5Saints -2
Raiders vs. DolphinsDolphins -7Dolphins -7Dolphins -7
Seahawks vs. 49ers49ers -6.549ers -6.549ers -7
Falcons vs. BroncosBroncos -2.5Broncos -1.5Broncos +1
Chiefs vs. BillsBills -2Bills -2.5Bills +1
Bengals vs. Chargers early picksChargers -1.5Chargers -1Chargers -1.5
Texans vs. Cowboys early picksCowboys +7.5Cowboys +7Cowboys +6.5
  • Divisional rivalry games remaining: Commanders vs. Eagles (TNF); Ravens vs. Steelers; Packers vs. Bears; Seahawks vs. 49ers
  • Half of the Week 11 games have opened with the home squad listed as the underdog
    • The Bills and Broncos have flipped to favorites as of Monday morning
  • Half the slate is lined with a spread of three or fewer points to open, and remain in that range as of Monday
  • Super Bowl odds contenders in the Kansas City Chiefs and Buffalo Bills square off in the most significant game on the slate
  • ATS leaders heading into Week 11: Commanders (7-2-1), Steelers (7-2), Lions (7-2), Colts (7-3), Cardinals (7-3), Broncos (7-3)
  • ATS losers heading into Week 11: Titans (1-8), Cowboys (2-7), Dolphins (2-6), Seahawks (2-6-1)
Kansas City Chiefs wide receiver DeAndre Hopkins celebrates with quarterback Patrick Mahomes as we look at the best Week 11 Odds & Betting Lines 
Kansas City Chiefs wide receiver DeAndre Hopkins celebrates with quarterback Patrick Mahomes after scoring a touchdown. Photo by: Denny Medley-Imagn Images

Best NFL Week 11 moneylines

(Odds via FanDuel)

GameNov. 14Nov. 11Opening moneyline (Nov. 6)
Jaguars vs. LionsLions -950Lions -820Lions -460
Packers vs. BearsBears +205Bears +235Bears +138
Rams vs. PatriotsPatriots +190Patriots +198Patriots +215
Browns vs. SaintsSaints -108Saints -134Saints -120
Vikings vs. TitansTitans +205Titans +235Titans +235
Colts vs. JetsJets -200Jets -164Jets -198
Raiders vs. DolphinsDolphins -360Dolphins -310Dolphins -375
Ravens vs. SteelersSteelers +152Steelers +144Steelers +168
Seahawks vs. 49ers49ers -29549ers -32049ers -330
Falcons vs. BroncosBroncos -136Broncos -118Broncos +100
Chiefs vs. BillsBills -134Bills -132Bills -108
Bengals vs. ChargersChargers -126Chargers -126Chargers -116
Texans vs. CowboysCowboys +295Cowboys +275Cowboys +230

Here are some of the major questions we asked going into Week 9, and the answers ahead of Week 10: 

  • How will the New Orleans Saints look with a new head coach after Dennis Allen was relieved of his duties ahead of Week 10?
    • They pulled off a large divisional victory over the Falcons and pulled away in early betting, but during the week things they have become a very small underdog
  • Joe Flacco fell short as Anthony Richardson's replacement in Week 9 for the Colts, but will he step it up in Week 10?
    • The Colts again did not look fantastic, failing to keep pace with the Bills; as of Thursday, Coach Steichen had reverted to Richardson as QB
  • How will the Dallas Cowboys look in Cooper Rush's first start for the injured Dak Prescott?
    • Not competitive, although like the Colts against the Bills, the Cowboys faced a tall task against the Eagles. The Texans won't be much easier.
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Best NFL Week 11 Over/Unders

(Odds via bet365)

GameNov. 14Nov. 11Opening Over/Unders (Nov. 6)
Ravens vs. Steelers48 (-110/-110)47 (-110/-110)45 (-110/-110)
Browns vs. Saints44.5 (-110/-110)44 (-110/-110)42 (-110/-110)
Packers vs. Bears40 (-110/-110)41.5 (-110/-110)44.5 (-110/-110)
Colts vs. Jets44 (110/-110)44 (110/-110)43.5 (-110/-110)
Jaguars vs. Lions46.5 (-110/-110)48 (-110/-110)50.5 (-110/-110)
Rams vs. Patriots43.5 (-110/-110)43.5 (-110/-110)44 (-110/-110)
Raiders vs. Dolphins44 (-110/-110)45.5 (-110/-110)45 (-110/-110)
Vikings vs. Titans39.5 (-110/-110)39.5 (-110/-110)41.5 (-110/-110)
Falcons vs. Broncos44 (-110/-110)44 (-110/-110)43 (-110/-110)
Seahawks vs. 49ers48 (-110/-110)49 (-110/-110)49 (-110/-110)
Chiefs vs. Bills46 (-110/-110)45.5 (-110/-110)46.5 (-110/-110)
Bengals vs. Chargers48 (-110/-110)46 (-110/-110)43 (-110/-110)
Texans vs. Cowboys42 (-110/-110)42 (-110/-110)43.5 (-110/-110)

44 (110/-11

  • Over leaders heading into Week 11: Ravens (9-1); Panthers (7-3), Bucs (7-3), Commanders (7-3), Bengals (7-3)
  • Under leaders heading into Week 11: Texans (2-8), Chargers (2-7), Giants (3-7), Bears (3-6), Vikings (3-6), Browns (3-6)
  • Opening market highs: The Jaguars vs. Lions is the only game lined at more than 50 points to open while sitting at 50.5
    • The Jags were forced to switch to Mac Jones at QB after Trevor Lawrence's injury was revealed and Jags-Lions has fallen to 46.5 in turn
    • Thursday Night Football's Commanders-Eagles (48.5) is the high mark for the week
  • Opening market lows: It's a rare week, but no games are lined with fewer than 40 points at open: the Vikings vs. Titans opening of 41.5 is the low watermark for the week.
    • That's now the lone game under 40 points, falling to 39.5 in early betting as the Titans remain inept offensively and the Vikings fell flat on Sunday
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