NFL Week 5 Odds & Betting Lines: Spreads, Moneyline, Over/Under
Week 5 of the NFL season features a Sunday Night Football showdown between two of the top Super Bowl contenders in the NFC, so let's examine the Week 5 odds and betting lines from our best NFL betting sites.
Nobody says it, but we're all thinking it: after watching seven hours of commercial-free football on NFL RedZone, sometimes it's hard to stay focused on a slow-moving Sunday Night Football matchup.
So, eat clean throughout the day, stay hydrated, and make sure you're well-rested for Sunday Night Football in Week 5 because we have one of the best matchups of the season on the horizon.
The San Francisco 49ers will be hosting the Dallas Cowboys, and the 49ers are favored by 4 points. There's a strong possibility that this is a preview of the NFC Championship, and the Super Bowl futures odds are likely to see some movement based on how this game plays out.
You can't afford to fall asleep in the fourth quarter of this one; you'll want all your best sports betting apps open and be closely monitoring any movements on the futures board.
Let's take a closer look at all the other opening odds for Week 5 of the NFL season via our best sports betting sites.
NFL Week 5 odd and lines
When betting on NFL markets, there's an advantage in getting to these NFL odds early and trying to beat any line movements. The closer you wait until Sunday to make your NFL picks, the more difficult it becomes to identify edges and secure the best price on the outcome you wish to bet on.
That's why it's important to start monitoring the NFL opening odds each week as soon as possible. This proactive approach will contribute to your long-term success in your sports betting endeavors.
Best NFL Week 5 spreads
| Game | Opening spread (Sept. 27) | Spread (Oct. 6) | Spread (Oct. 2) |
|---|---|---|---|
| Jaguars vs. Bills | Bills -4.5 | Bills -5.5 | Bills -5.5 |
| Titans vs. Colts | Colts -1 | Titans -2.5 | Colts -1 |
| Texans vs. Falcons | Falcons -3.5 | Falcons -1.5 | Falcons -2.5 |
| Giants vs. Dolphins | Dolphins -10 | Dolphins -12 | Dolphins -9.5 |
| Ravens vs. Steelers | Ravens -2.5 | Ravens -4.5 | Ravens -4 |
| Panthers vs. Lions | Lions -7 | Lions -10 | Lions -9 |
| Saints vs. Patriots | Patriots -2.5 | Pick | Patriots -1.5 |
| Eagles vs. Rams | Eagles -6 | Eagles -4 | Eagles -5 |
| Bengals vs. Cardinals | Bengals -7.5 | Bengals -3 (-115) | Bengals -4 |
| Jets vs. Broncos | Broncos -3 | Broncos -2.5 | Broncos -2.5 (-115) |
| Chiefs vs. Vikings | Chiefs -6 | Chiefs -3.5 | Chiefs -5.5 |
| Cowboys vs. 49ers | 49ers -3 | 49ers -4 | 49ers -3.5 |
| Packers vs. Raiders | Packers -1 | Raiders -1 | Packers -1 |
We have an exciting matchup lined up for Sunday Night Football in Week 5, where the Dallas Cowboys will be visiting the San Francisco 49ers at Levi's Stadium in Santa Clara. This game could potentially serve as a preview for the NFC Championship, assuming the Cowboys don't face the Arizona Cardinals in the playoffs.
The 49ers open as 3-point home favorites against the Cowboys. It'll be interesting to see how the sportsbooks adjust the line through multiple key numbers for a primetime game that should generate a ton of two-way action.
Best NFL Week 5 moneylines
| Game | Opening moneyline (Sept. 27) | Moneyline (Oct. 6) | Moneyline (Oct. 2) |
|---|---|---|---|
| Jaguars vs. Bills | Bills (-205) | Bills (-238) | Bills (-245) |
| Giants vs. Dolphins | Dolphins (-500) | Dolphins (-675) | Dolphins (-440) |
| Panthers vs. Lions | Lions (-375) | Lions (-485) | Lions (-425) |
| Texans vs. Falcons | Falcons (-185) | Falcons (-122) | Falcons (-120) |
| Ravens vs. Steelers | Ravens (-125) | Ravens (-218) | Ravens (-185) |
| Titans vs. Colts | Colts (-118) | Titans (-130) | Colts (-120) |
| Saints vs. Patriots | Patriots (-125) | Patriots (-112) | Patriots (-120) |
| Eagles vs. Rams | Eagles (-250) | Eagles (-218) | Eagles (-218) |
| Bengals vs. Cardinals | Bengals (-425) | Bengals (-162) | Bengals (-175) |
| Chiefs vs. Vikings | Chiefs (-285) | Chiefs (-185) | Chiefs (-225) |
| Jets vs. Broncos | Broncos (-166) | Broncos (-135) | OTB |
| Cowboys vs. 49ers | 49ers (-166) | 49ers (-180) | 49ers (-170) |
| Packers vs. Raiders | Packers (-115) | Raiders (-112) | Packers (-122) |
If you placed a bet on the Cincinnati Bengals' moneyline on the lookahead line against the Arizona Cardinals for Week 5, you won't be able to share any posts about the closing line value you received for this bet.
The Bengals were -425 favorites on the moneyline on the lookahead line, but after another spirited effort by the Cardinals in Week 4 and the Bengals getting demolished by the Tennessee Titans 27-3, that line has now moved to Bengals -162.
Typically, we only see the lines move by cents, not multiple dollars.
Best NFL Week 5 Over/Unders
| Game | Opening Over/Under (Sept. 27) | Over/Under (Oct. 6) | Over/Under (Oct. 2) |
|---|---|---|---|
| Jaguars vs. Bills | 47.5 (-110/-110) | 48.5 (-110/-110) | 48 (-110/-110) |
| Ravens vs. Steelers | 41.5 (-110/-110) | 38 (-110/-110) | 40 (-110/-110) |
| Panthers vs. Lions | 43.5 (-110/-110) | 44 (-110/-110) | 43.5 (-110/-110) |
| Texans vs. Falcons | 41.5 (-110/-110) | 41.5 (-110/-110) | 41 (-110/-110) |
| Saints vs. Patriots | 40.5 (-110/-110) | 39 (-110/-110) | 39 (-110/-110) |
| Giants vs. Dolphins | 49.5 (-110/-110) | 47.5 (-110/-110) | 49.5 (-110/-110) |
| Titans vs. Colts | 42.5 (-110/-110) | 43 (-110/-110) | 42 (-110/-110) |
| Bengals vs. Cardinals | 42.5 (-110/-110) | 44.5 (-110/-110) | 42.5 (-110/-110) |
| Eagles vs. Rams | 46.5 (-110/-110) | 50 (-110/-110) | 48 (-110/-110) |
| Chiefs vs. Vikings | 52 (-110/-110) | 52.5 (-110/-110) | 52.5 (-110/-110) |
| Jets vs. Broncos | 40 (-110/-110) | 43.5 (-110/-110) | 41 (-110/-110) |
| Cowboys vs. 49ers | 45.5 (-110/-110) | 45 (-110/-110) | 45 (-110/-110) |
| Packers vs. Raiders | 43.5 (-110/-110) | 44.5 (-110/-110) | 43.5 (-110/-110) |
Keep an eye on the total for the matchup between the Houston Texans and Atlanta Falcons. Rookie quarterback CJ Stroud has absolutely been slinging it in his first four games in the NFL, which is sure to have some bettors eyeing that low total of 41.5. But there's another factor potentially at play here that could move that number.
Desmond Ridder is on borrowed time as the Falcons' starting quarterback, and everyone's favorite backup is waiting behind him on the depth chart. If the Falcons make the move to Taylor Heinicke, that total will close a couple of points higher than the 41.5 we're currently seeing it trade at.
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Related pages
- Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)
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