NFL Week 5 Predictions: Picks & Odds for Marquee Games

The Super Bowl odds continue to move every week, and the 14-game Week 5 slate featured several highly impactful matchups.

The Kansas City Chiefs remain undefeated and the Super Bowl favorites. The Baltimore Ravens climbed the rankings with Sunday's win over the rival Cincinnati Bengals, and the Minnesota Vikings are the most surprising 5-0 team as we cross over the season's quarter-pole.

C Jackson Cowart looks ahead with his NFL Week 6 early picks.

NFL picks & predictions Week 5

Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

• Saints vs. Chiefs early picks (MNF)
• Saints vs. Chiefs prediction
• Saints vs. Chiefs MNF player prop bets
• Saints vs. Chiefs MNF parlay
• Patrick Mahomes MNF player prop bets
• Travis Kelce player props
• First touchdown scorer predictions for MNF
• Anytime touchdown scorer predictions for MNF

Don't miss the rest of our Week 5 NFL picks. Listed odds for all games via bet365 unless stated otherwise.

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NFL odds for Monday

Saints vs. Chiefs odds

Prediction: Saints +5.5 (-105 via FanDuel) vs. Chiefs ⭐⭐⭐⭐⭐

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Pick made by Mike Spector.

• When: Monday, Oct. 7 - 8:15 p.m. ET
• Where: GEHA Field at Arrowfield Stadium, Kansas City
• How to watch: ESPN
• Moneyline: Saints +200 | Chiefs -245
• Spread: Saints +5.5 (-110) | Chiefs -5.5 (-110)
• Total: 42.5 (-110/-110)

NFL picks roundup: Week 5

• NFL survivor picks
• NFL Week 5 against the spread
• NFL upset picks Week 5
• NFL predictions & best bets Week 5
• Anytime touchdown scorer predictions
• Touchdown parlay Week 5
• NFL player props Week 5

NFL betting odds pages

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• bet365 Bonus Code: SBRBONUS | Read our bet365 Review
• FanDuel Promo Code | Read our FanDuel Review
• DraftKings Promo Code | Read our DraftKings Review

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Related pages

• Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)