NFL Week 5 Predictions: Picks & Odds for Marquee Games

Four teams are on bye this week, knocking us down to a 14-game slate for our NFL Week 5 predictions.

Esten McLaren

Last Updated: October 7, 2024 2:01 PM EDT • 3 minute read

Kansas City Chiefs wide receiver Xavier Worthy hangs on to a touchdown pass as we look at our NFL Week 5 predicitons. — Kansas City Chiefs wide receiver Xavier Worthy hangs on to a touchdown pass. Photo Credit: Jayne Kamin-Oncea-Imagn Images.

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The Super Bowl odds continue to move every week, and the 14-game Week 5 slate featured several highly impactful matchups.

The Kansas City Chiefs remain undefeated and the Super Bowl favorites. The Baltimore Ravens climbed the rankings with Sunday's win over the rival Cincinnati Bengals, and the Minnesota Vikings are the most surprising 5-0 team as we cross over the season's quarter-pole.

C Jackson Cowart looks ahead with his NFL Week 6 early picks.

NFL picks & predictions Week 5

Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Saints vs. Chiefs early picks (MNF)

Saints vs. Chiefs prediction
Saints vs. Chiefs MNF player prop bets
Saints vs. Chiefs MNF parlay
Patrick Mahomes MNF player prop bets
Travis Kelce player props
First touchdown scorer predictions for MNF
Anytime touchdown scorer predictions for MNF

Don't miss the rest of our Week 5 NFL picks. Listed odds for all games via bet365 unless stated otherwise.

NFL odds for Monday

Saints vs. Chiefs odds

Prediction: Saints +5.5 (-105 via FanDuel) vs. Chiefs ⭐⭐⭐⭐⭐

Pick made by Mike Spector.

When: Monday, Oct. 7 - 8:15 p.m. ET
Where: GEHA Field at Arrowfield Stadium, Kansas City
How to watch: ESPN
Moneyline: Saints +200 | Chiefs -245
Spread: Saints +5.5 (-110) | Chiefs -5.5 (-110)
Total: 42.5 (-110/-110)

NFL picks roundup: Week 5

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Written by:
Esten McLaren

Esten is the Content Manager for SportsbookReview.com. He has been in the sports betting industry since the legalization of mobile sports betting in New Jersey, and he has worked with Sportsbook Review before the launch of sports betting in Ontario. In writing and personal betting, Esten focuses on golf and the NFL, while dabbling in futures bets across all major North American sports, looking for edges with long shots. His favorite markets to research and bet include golf outrights and NFL touchdown scorers, where he looks for edges in pricing differences, and player skill sets against the opponent (or golf course). He prefers DraftKings as it is often first-to-market with golf odds each week and next year's futures odds. Esten's previous stops include time with GolfWeek. He previously worked in the fantasy sports industry with FNTSY Sports Network, theScore, and USA TODAY, where he started to build his NFL and golf betting experience. Esten graduated from the College of Sports Media with a diploma in Radio and Television Sports Broadcasting. He has appeared on FNTSY Sports Network, VSiN, and VSiN's Long Shots podcast, where he correctly called Will Zalatoris as the winner of the 2022 FedEx St. Jude Championship. Esten looks at sports betting much like golf and advises beginner bettors to compete against themselves rather than being concerned with what others may or may not be doing based on social media claims.