NFL Week 2 Odds: Updated Betting Lines Ahead of Thursday Night Football
The defending champion Kansas City Chiefs wasted no time putting the league on notice: the Super Bowl odds favorite—and the feature of our Super Bowl predictions—hasn't gone away. The San Francisco 49ers did the same on Monday Night without their biggest star.
Survivor pools crumbled as the New England Patriots stunned the Cincinnati Bengals. First-overall draft pick Caleb Williams avoided blunders while winning his first game as the Chicago Bears rallied to beat the Tennessee Titans. We were treated to overtime as the Sunday Night Football odds favorite Detroit Lions snuck out a victory over the Los Angeles Rams.
The Dolphins were home favorites by the Thursday Night Football odds, but they dropped the game to the visiting Buffalo Bills. Miami also suffered a big blow as QB Tua Tagovailoa sustained another concussion.
The week ends with a battle of the birds as the Monday Night Football odds favorite Philadelphia Eagles visit the Atlanta Falcons.
NFL Week 2 odd and lines
When betting on NFL markets, there's an advantage in getting to these NFL odds early and trying to beat any line movements. The closer you wait until Sunday to make your NFL picks, the more difficult it becomes to identify edges and secure the best price on the outcome you wish to bet on.
That's why it's important to start monitoring the odds each week as soon as possible. This proactive approach will contribute to your long-term success in sports betting endeavors.
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Best NFL Week 2 spreads
(Odds via bet365)
| Game | Sept. 14 | Sept. 12 | Sept. 10 | Sept. 6 |
|---|---|---|---|---|
| Browns vs. Jaguars | Jaguars -3 | Jaguars -3 | Jaguars -3.5 | Jaguars -2 |
| Colts vs. Packers | Packers +2.5 | Packers +2.5 | Packers +3.5 | Packers -4.5 |
| Chargers vs. Panthers | Panthers +5 | Panthers +6 | Panthers +6.5 | Panthers +3.5 |
| Raiders vs. Ravens | Ravens -8.5 | Ravens -8.5 | Ravens -9.5 | Ravens -7.5 |
| Saints vs. Cowboys | Cowboys -6 | Cowboys -6 | Cowboys -6.5 | Cowboys -6.5 |
| Giants vs. Commanders | Commanders -1.5 | Commanders -1.5 | Commanders -2.5 | Commanders -2.5 |
| Jets vs. Titans | Titans +3.5 | Titans +4 | Titans +4 | Titans +4 |
| Seahawks vs. Patriots | Patriots +3 | Patriots +3.5 | Patriots +3.5 | Patriots +3.5 |
| 49ers vs. Vikings | Vikings +4.5 | Vikings +5 | Vikings +6 | Vikings +6.5 |
| Buccaneers vs. Lions | Lions -7.5 | Lions -7.5 | Lions -6.5 | Lions -6.5 |
| Rams vs. Cardinals | Cardinals -1 | Cardinals -1 | Cardinals -1.5 | Cardinals +2.5 |
| Bengals vs. Chiefs | Chiefs -6 | Chiefs -6 | Chiefs -6 | Chiefs -3.5 |
| Steelers vs. Broncos | Broncos +2.5 | Broncos +2.5 | Broncos +3 | Broncos +3 |
| Bears vs. Texans | Texans -6.5 | Texans -6.5 | Texans -6.5 | Texans -3.5 |
| Falcons vs. Eagles | Eagles -6.5 | Eagles -6.5 | Eagles -6.5 | Eagles -3.5 |
After a Week 1 slate with 11 games lined at 3.5 points or fewer, Week 2 lines are a little larger. Only six games are lined at 3 or fewer points just 24 hours from Sunday's action.
After a week with just two home underdogs, the oddsmakers expect more road victories in Week 2. Six teams are lined as home dogs, with the Packers and the Cardinals flip-flopping roles due to injuries.
The week got underway with a road 'dog picking up a win, too, as the Bills handled the Dolphins on TNF.
The Packers have flipped 7 points on the news of Love's injury; the Cardinals have gained 3.5 points due to the Rams' injuries.
Lackluster performances have boosted two other teams by 3 points, as the Texans and Eagles are giving up 3 points more than last week.
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Best NFL Week 2 moneylines
(Odds via FanDuel)
| Game | Sept. 14 | Sept. 12 | Sept. 10 | Sept. 6 |
|---|---|---|---|---|
| Saints vs. Cowboys | Cowboys -260 | Cowboys -280 | Cowboys -295 | Cowboys -280 |
| Buccaneers vs. Lions | Lions -330 | Lions -330 | Lions -310 | Lions -335 |
| Browns vs. Jaguars | Jaguars -164 | Jaguars -164 | Jaguars -186 | Jaguars -126 |
| 49ers vs. Vikings | Vikings +184 | Vikings +198 | Vikings +215 | Vikings +235 |
| Chargers vs. Panthers | Panthers +205 | Panthers +215 | Panthers +240 | Panthers +132 |
| Raiders vs. Ravens | Ravens -430 | Ravens -480 | Ravens -430 | Ravens -450 |
| Seahawks vs. Patriots | Patriots +154 | Patriots +162 | Patriots +148 | Patriots +168 |
| Colts vs. Packers | Packers +132 | Packers +132 | Packers +148 | Packers -196 |
| Jets vs. Titans | Titans +166 | Titans +172 | Titans +162 | Titans +166 |
| Giants vs. Commanders | Commanders -130 | Commanders -116 | Commanders -146 | Commanders -138 |
| Rams vs. Cardinals | Cardinals -112 | Cardinals -120 | Cardinals -112 | Cardinals +108 |
| Bengals vs. Chiefs | Chiefs -260 | Chiefs -235 | Chiefs -260 | Chiefs -190 |
| Steelers vs. Broncos | Broncos +130 | Broncos +130 | Broncos +134 | Broncos +116 |
| Bears vs. Texans | Texans -295 | Texans -295 | Texans -270 | Texans -205 |
| Falcons vs. Eagles | Eagles -310 | Eagles -320 | Eagles -300 | Eagles -200 |
We were spoiled in Week 1 with a bonus Friday night game. In Week 2, things are settling into the normal Thursday - Sunday - Monday routine.
The AFC East clash between the Bills and Dolphins looked like a highlight of the Week 2 slate, but the game was a bit of a dud.
But the battle between the AFC-contending Bengals and Chiefs has lost some steam after Cincinnati came out flat in Week 1.
A clash between No. 1 overall draft pick Williams and the reigning Offensive Rookie of the Year, C.J. Stroud of the Houston Texans, has lost some steam, as Williams looked like a rookie in Week 1.
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Best NFL Week 2 Over/Unders
(Odds via bet365)
| Game | Sept. 14 | Sept. 12 | Sept. 10 | Sept. 6 |
|---|---|---|---|---|
| Browns vs. Jaguars | 41.5 (-110/-110) | 41.5 (-110/-110) | 41.5 (-110/-110) | 44.5 (-110/-110) |
| Colts vs. Packers | 40.5 (-110/-110) | 41 (-110/-110) | 40.5 (-110/-110) | 47 (-110/-110) |
| Chargers vs. Panthers | 39 (-110/-110) | 39 (-110/-110) | 39.5 (-110/-110) | 41.5 (-110/-110) |
| Raiders vs. Ravens | 41.5 (-110/-110) | 41.5 (-110/-110) | 41.5 (-110/-110) | 44 (-110/-110) |
| Saints vs. Cowboys | 46.5 (-110/-110) | 46.5 (-110/-110) | 45.5 (-110/-110) | 44.5 (-110/-110) |
| Giants vs. Commanders | 43.5 (-110/-110) | 43 (-110/-110) | 44 (-110/-110) | 41.5 (-110/-110) |
| Jets vs. Titans | 41 (-110/-110) | 41 (-110/-110) | 42 (-110/-110) | 43.5 (-110/-110) |
| Seahawks vs. Patriots | 38.5 (-110/-110) | 38.5 (-110/-110) | 37.5 (-110/-110) | 41 (-110/-110) |
| 49ers vs. Vikings | 46.5 (-110/-110) | 46.5 (-110/-110) | 45.5 (-110/-110) | 46 (-110/-110) |
| Buccaneers vs. Lions | 51.5 (-110/-110) | 51.5 (-110/-110) | 51 (-110/-110) | 48.5 (-110/-110) |
| Rams vs. Cardinals | 47.5 (-110/-110) | 48 (-110/-110) | 49.5 (-110/-110) | 48 (-110/-110) |
| Bengals vs. Chiefs | 48 (-110/-110) | 48 (-110/-110) | 48 (-110/-110) | 48.5 (-110/-110) |
| Steelers vs. Broncos | 36.5 (-110/-110) | 36.5 (-110/-110) | 36.5 (-110/-110) | 40.5 (-110/-110) |
| Bears vs. Texans | 45.5 (-110/-110) | 45.5 (-110/-110) | 46 (-110/-110) | 46.5 (-110/-110) |
| Falcons vs. Eagles | 47.5 (-110/-110) | 47 (-110/-110) | 47 (-110/-110) | 48.5 (-110/-110) |
The Week 1 games have impacted these lines as expected, as three have dipped below 40 since opening.
Last season, we routinely saw very low totals, and oddsmakers seemed to expect that to change in Week 1. That's already switched a bit; we have three games lined at fewer than 40 points.
Sputtering offense from the Chargers, Panthers, Seahawks, Patriots, Steelers, and Broncos have dropped their lines significantly - and really, unless things change in a big way in Week 2, these squads are going to be weekly candidates for low totals.
For the second straight week, just one game is lined with a total above 50 points, as the Bucs and Lions have been steamed up to 51.5 points. Week 1's only 50-pointer closed at 54 and ended with 46 points. Will the Under cash on Sunday afternoon as well?
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More Week 2 NFL odds
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