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Week 1 NFL Odds & Lines 2023: Matchups Set for International Series, Black Friday, Christmas Day & More

Esten McLaren

Last Updated: May 12, 2023 8:48 AM EDT • 28 min 29 sec read.

Kansas City Chiefs' quarterback Patrick Mahomes runs with the ball as we look at the NFL odds and lines for 2023
Kansas City Chiefs' quarterback Patrick Mahomes runs with the ball during Super Bowl LVII between the Kansas City Chiefs and the Philadelphia Eagles at State Farm Stadium in Glendale, Arizona, on February 12, 2023. Photo by Timothy A. Clary via AFP.

The 2023 NFL schedule was released Thursday, May 11, and the early Week 1 NFL odds and lines are out. Read on as we look at the early Week 1 NFL odds and lines from our best NFL betting sites for the season opener, along with odds for the NFL International Series, Black Friday, Christmas Day, and more!

What offseason?

If the NBA and NHL playoffs (and the early stages of the MLB season) weren't enough for you, our best sports betting apps have released early Week 1 NFL odds and lines as well as odds for several other key matchups on the 2023 schedule. And we can start making our NFL picks!

In addition to continuing to watch the 2024 Super Bowl odds and scouting the NFL projected win totals, bettors can now start studying the season-opening matchup between the Super Bowl champion Kansas City Chiefs and Detroit Lions and the rest of the Week 1 schedule, as well as the five matchups making up the NFL's 2023 International Series, the first-ever Black Friday game, and the Christmas Day and New Year's Eve matchups.

Read on as we look at the best early Week 1 NFL odds and lines for the 2023 NFL season (odds via our best sports betting sites).

NFL odds and lines for 2023: Week 1

NFL Kickoff: Lions vs. Chiefs - Thursday, Sept. 7 at 8:20 p.m. ET

DraftKingsFanDuelBetMGMCaesars
Lions+6.5 (+100)+6.5 (-105)+7 (-110)+7 (-110)
Chiefs-6.5 (-120)-6.5 (-115)-7 (-110)-7 (-110)
Total53.5 (-110/-110)53.5 (-110/-110)54.5 (-105/-115)54 (-110/-110)

Sunday, Sept. 10 schedule

MatchupDraftKingsFanDuelBetMGMCaesars
Bengals vs. Chiefs (1 p.m. ET)CIN -2.5 (-110)CIN -2.5 (-110)CIN -2.5 (-110)CIN -2.5 (-110)
Titans vs. Saints (1 p.m. ET)NO -3.5 (-110)NO -4 (-110)NO -3.5 (-110)NO -3.5 (-110)
49ers vs. Steelers (1 p.m. ET)SF -3 (-105)SF -2.5 (-115)SF -3 (-110)SF -3 (-110)
Panthers vs. Falcons (1 p.m. ET)ATL -2.5 (-110)ATL -1.5 (-110)ATL -2.5 (-110)ATL -3 (-105)
Cardinals vs. Commanders (1 p.m. ET)WAS -5 (-110)WAS -6 (-110)WAS -5.5 (-115)WAS -5.5 (-110)
Jaguars vs. Colts (1 p.m. ET)JAX -3.5 (-110)JAX -4 (-110)JAX -3.5 (-110)JAX -3.5 (-110)
Texans vs. Ravens (1 p.m. ET)BAL -9 (-110)BAL -9.5 (-110)BAL -9.5 (-110)BAL -9 (-110)
Buccaneers vs. Vikings (1 p.m. ET)MIN -7 (-105)MIN -5.5 (-110)MIN -6.5 (-115)MIN -7 (+105)
Rams vs. Seahawks (4 p.m. ET)SEA -5.5 (-110)SEA -4.5 (-110)SEA -5.5 (-110)SEA -5.5 (-110)
Raiders vs. Broncos (4:25 p.m. ET)DEN -3.5 (-110)DEN -4 (-110)DEN -3 (-110)DEN -3 (-110)
Dolphins vs. Chargers (4:25 p.m. ET)LAC -2.5 (-115)LAC -2 (-115)LAC -2.5 (-110)LAC -2.5 (-110)
Packers vs. Bears (4:25 p.m. ET)CHI -2.5 (-110)CHI -1 (-110)CHI -2.5 (-105)CHI -2.5 (-110)
Eagles vs. Patriots (4:25 p.m. ET)PHI -3.5 (-110)PHI -3.5 (-110)PHI -4.5 (-115)PHI -5 (-110)
Cowboys vs. Giants (4:25 p.m. ET)DAL -2.5 (-110)DAL -2.5 (-115)DAL -3 (-110)DAL -2.5 (-110)

Monday Night Football: Bills vs. Jets - Monday, Sept. 11 at 8:20 p.m. ET

DraftKingsFanDuelBetMGMCaesars
Bills-1.5 (-110)-1.5 (-115)-1.5 (-110)-1 (-110)
Jets+1.5 (-110)+1.5 (-105)+1.5 (-110)+1 (-110)
Total48 (-110/-110)47.5 (-112/-108)47.5 (-110)47 (-110/-110)

NFL odds and lines for 2023: International Series

Falcons vs. Jaguars - Sunday, Oct. 1 at 9:30 a.m. ET (Week 4)

Wembley Stadium, London

DraftKingsFanDuel
Falcons+4 (-110)+4.5 (-110)
Jaguars-4 (-110)-4.5 (-110)

Jaguars vs. Bills - Sunday, Oct. 8 at 9:30 a.m. ET (Week 5)

Tottenham Hotspur Stadium, London

DraftKingsFanDuel
Jaguars+3.5 (-110)+3.5 (-115)
Bills-3.5 (-110)-3.5 (-105)

Ravens vs. Titans - Sunday, Oct. 15 at 9:30 a.m. ET (Week 6)

Tottenham Hotspur Stadium, London

DraftKingsFanDuel
Ravens-5.5 (-110)-5.5 (-110)
Titans+5.5 (-110)+5.5 (-110)

Dolphins vs. Chiefs - Sunday, Nov. 5 at 9:30 a.m. ET (Week 9)

Frankfurt Stadium, Frankfurt

DraftKingsFanDuel
Dolphins+5.5 (-110)+5.5 (-110)
Chiefs-5.5 (-110)-5.5 (-110)

Colts vs. Patriots - Sunday, Nov. 12 at 9:30 a.m. ET (Week 10)

Frankfurt Stadium, Frankfurt

DraftKingsFanDuel
Colts+5 (-110)+5 (-110)
Patriots-5 (-110)-5 (-110)

NFL odds and lines for 2023: Thanksgiving (Week 12)

Packers vs. Lions - Thursday, Nov. 23 at 12:30 p.m. ET

DraftKings
Packers+4 (-110)
Lions-4 (-110)

Commanders vs. Cowboys - Thursday, Nov. 23 at 4:30 p.m. ET

DraftKings
Commanders+5.5 (-110)
Cowboys-5.5 (-110)

49ers vs. Seahawks - Thursday, Nov. 23 at 8:20 p.m. ET

DraftKings
49ers-1.5 (-110)
Seahawks+1.5 (-110)

NFL odds and lines for 2023: Black Friday

Dolphins vs. Jets - Friday, Nov. 24 at 3 p.m. ET (Week 12)

DraftKingsFanDuel
Dolphins+2.5 (-105)+2.5 (-110)
Jets-2.5 (-115)-2.5 (-110)

NFL odds and lines for 2023: Christmas Day

Raiders vs. Chiefs - Monday, Dec. 25 at 1 p.m. ET (Week 16)

DraftKingsFanDuel
Raiders+8.5 (-110)+9.5 (-110)
Chiefs-8.5 (-110)-9.5 (-110)

Giants vs. Eagles - Monday, Dec. 25 at 4:30 p.m. ET (Week 16)

DraftKingsFanDuel
Giants+7 (-110)+7.5 (-105)
Eagles-7 (-110)-7.5 (-115)

NFL odds and lines for 2023: New Year's Eve

Bengals vs. Chiefs - Sunday, Dec. 31 at 4:25 p.m. ET (Week 17)

DraftKingsFanDuel
Bengals+3.5 (-115)+3.5 (-115)
Chiefs-3.5 (-105)-3.5 (-105)

Key dates for the 2023 NFL season

When will the 2023 NFL preseason begin?

The 2023 NFL preseason will begin with the Hall of Fame Game between the Cleveland Browns and New York Jets on Thursday, Aug. 3.

When will the 2023 NFL regular season begin?

The 2023 NFL season will begin on Thursday, Sept. 7 with the Detroit Lions taking on the Kansas City Chiefs in the NFL's 2023 Kickoff Game.

When will the 2023 NFL season end?

The 2023 NFL regular season will conclude with Week 18 on Sunday, Jan. 7.

When is the 2024 Super Bowl?

The 2024 Super Bowl will be played Sunday, Feb. 11 at Allegiant Stadium in Las Vegas.

NFL futures 2023

Here are our best NFL betting sites:

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Written By:
Esten McLaren
Esten is the Senior Publishing Editor for SportsbookReview.com. He previously spent time as the Managing Editor of SportsbookWire.com, and he has done freelance work in sports betting for TheLines, PlayPicks, and BettingPros. He's well versed in the NFL, NHL, MLB, and NBA, but his true passion is with the PGA Tour. Esten's always happy to chase a long shot and will never shy away from a futures bet, but he'll never stop backing Rory McIlroy in majors. He's also a recovering Ottawa Senators and Atlanta Falcons fan. Always bet against the Toronto Maple Leafs at plus money.