NFL Predictions Week 5 2023: Picks & Odds for ALL Games

Rounding up our best NFL picks and predictions for Week 5. ML, ATS, O/U, and prop plays for a big payday.
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Our NFL predictions for Week 5 have you covered for the first shortened week of the season as four teams are on a bye while we look to get the best of the NFL odds.

The NFL's Week 5 Sunday slate opens with the Jacksonville Jaguars playing the Buffalo Bills in London, England as Sunday's slate will kick off nice and early at 9:30 a.m. ET once again. The marquee game of the week has the San Francisco 49ers hosting the Dallas Cowboys on Sunday Night Football as a potential NFC Championship preview.

Meanwhile, the Cleveland Browns, Los Angeles Chargers, Seattle Seahawks, and Tampa Bay Buccaneers will all enjoy an early-season bye. Fans of those teams can go ahead and starting looking at the NFL Week 6 odds and lines.

Here are our best NFL predictions for Week 5 based on the NFL Week 5 odds.

NFL picks and predictions for Week 5

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NFL Week 5 predictions: Monday

Packers vs. Raiders pick: Aaron Jones Over 48.5 rushing yards (-110 via bet365) ⭐⭐⭐⭐

Packers-Raiders pick made by Mike Spector

NFL Week 5 expert picks

NFL Week 5 promo codes

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NFL betting odds pages

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