NFL Predictions Week 6 2023: Picks & Odds for ALL Games

Rounding up our best NFL picks and predictions for Week 6. ML, ATS, O/U, and prop plays for a big payday.

Esten McLaren

Last updated: October 16, 2023 3:42 PM EDT • 4 min read

All but two teams are in action for the NFL's Week 6 with the Sunday slate starting in London, England once again as we round up all of our betting experts' top NFL predictions for Week 6 while looking to get the best of the NFL odds.

Tottenham Hotspur Stadium in London, England plays host to the Baltimore Ravens and Tennessee Titans and their 9:30 a.m. ET start on Sunday morning. The Buffalo Bills host the New York Giants on Sunday Night Football, and Monday Night Football pits the Los Angeles Chargers against the wound-licking Dallas Cowboys.

The Green Bay Packers and Pittsburgh Steelers are the two teams on byes this week.

Here are our best NFL predictions for Week 6 based on the NFL Week 6 odds.

NFL picks and predictions for Week 6

NFL Week 6 predictions: Monday

Cowboys ML vs. Chargers pick: (-130 via bet365) ⭐⭐⭐

Cowboys-Chargers pick made by Mike Spector

NFL Week 6 expert picks

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Written By:
Esten McLaren

Esten is the Senior Publishing Editor for SportsbookReview.com. He has been in the sports betting industry since the legalization of mobile sports betting in New Jersey, and with SportsbookReview prior to the launch of sports betting in Ontario. Esten's previous stops include the USA TODAY network, including GolfWeek. He previously worked in the fantasy sports industry, with FNTSY Sports Network, theScore, and USA TODAY. Esten graduated from the College of Sports Media with a diploma in Radio and Television Sports Broadcasting after acquiring a degree in Biological Sciences from the University of Guelph. He has appeared on FNTSY Sports Network, VSiN, and VSiN's Long Shots podcast, where he correctly called Will Zalatoris as the winner of the 2022 FedEx St. Jude Championship. Esten is a big proponent of the entertainment side of sports betting and loves to dip his toes into the novelty and alt-markets while chasing long shots with reduced wagers on golf outrights and futures markets. He's also been known to sprinkle some lunch money on touchdown-scorer parlays with two notable hits still funding his bankroll. Esten looks at sports betting much like golf and advises beginner bettors to compete against themselves rather than being concerned with what others may or may not be doing based on social media claims.