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Geno Smith of the Seattle Seahawks looks to pass against the Carolina Panthers during the first quarter as we look at all of our NFL Week 4 predictions.
Geno Smith of the Seattle Seahawks looks to pass against the Carolina Panthers during the first quarter. Photo by Steph Chambers/Getty Images/AFP.

Our NFL predictions for Week 4 are all rounded up here as the standings are starting to shake up and teams - and coaches - start to feel the pressure. Tail our NFL betting experts as we look for value in the odds from our best NFL betting sites.

A jam-packed Week 4 concludes with the New York Giants hosting the Seattle Seahawks on Monday Night Football. The sliding Giants have been walloped twice and needed a significant second-half comeback to beat the Arizona Cardinals. Meanwhile, the Seahawks have won two straight games, with their sizzling offense scoring 37 points during both of those victories.

There's just one game on Monday in the NFL's final week before byes begin. Start preparing for next week with our breakdown of the opening NFL Week 5 odds and lines.

Here are our best NFL predictions for Week 4 based on the NFL Week 4 odds.

NFL picks and predictions for Week 

NFL Week 4 predictions: Monday

Seahawks vs. Giants: Over 47 (-109 via BetRivers) ⭐⭐⭐⭐

Seahawks vs. Giants pick made by Mike Spector

NFL Week 4 expert picks

Kentucky bettors: Sports betting is here!

Kentucky sports betting launched on Sept. 28 - so sign up with the best Kentucky sportsbook promos now! And check out our list of the best Kentucky sports betting apps!

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NFL betting odds pages

Check out our best NFL betting sites:

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