Most Regular Season Rushing Yards Odds 2023: McCaffrey a Runaway Favorite

Check out our NFL most regular-season rushing yards odds.

NFL odds are out at the best sports betting sites for player futures markets such as the most regular-season passing yardsreceiving yards, and rushing yards. Here's a look at the odds and our picks and predictions to be the NFL's leader in regular-season rushing yards in 2023.

San Francisco 49ers tailback Christian McCaffrey built a big lead in the most rushing yards race through four games before returning to the pack. However, McCaffrey is now pulling away again with just three weeks remaining, and this competition is just about over.

Here are the latest odds on the running back to record the most regular-season rushing yards in 2023, using odds from our best NFL betting sites.

Most regular season rushing yards odds 2023

(odds as of Dec. 19)

Player DraftKings bet365
Christian McCaffrey -10000  -5000 
Kyren Williams +2000 +2500
Raheem Mostert +2500  +2200
James Cook +3000 +3000
D'Andre Swift +5000  +5000 
Derrick Henry +10000 +15000

Most regular-season rushing yards odds movement

McCaffrey became the favorite in this market after the Cleveland Browns' Nick Chubb suffered a season-ending knee injury in Week 2. He had been pulling away until suffering an injury of his own in Week 6. The injury didn't cost him any time, but it impacted his game and allowed the competition to catch up in October.

However, he rushed for 287 combined yards through three games in November and tagged the mighty Eagles defense for 93 yards in Week 13. Then, in Week 14, McCaffrey uncorked his best effort since Week 1 with 145 yards on the ground vs. the Seahawks. He followed it up with 115 yards on the ground vs. the Cardinals in Week 15.

McCaffrey's tearaway 300-yard lead has caused chaos at our best sports betting sites, with FanDuel pulling their odds after Week 14 and BetMGM following suit after Week 15. DraftKings and bet365 have essentially declared this race over, practically daring long-shot players to plunk a bet down. The latter has McCaffrey at better odds, though -5000 is hardly appealing.

Most regular-season rushing yards 2023: Favorite

Christian McCaffrey (-5000 via bet365)

Run CMC is the current favorite in this category, and he's also among the betting favorites in the Offensive Player of the Year odds. He leads the league in rushing by over 300 yards and averages 5.3 yards per carry. He's also tops in attempts. 

Even if McCaffrey hardly plays the final three weeks due to a sudden and serious injury, it would still take a strong stretch run from Raheem Mostert, Kyren Williams, or James Cook to make this a race again.

Regular-season rushing yards leaders

Season Player Yards
2022 Josh Jacobs 1,653
2021 Jonathan Taylor 1,811
2020 Derrick Henry 2,027
2019 Derrick Henry 1,540
2018 Ezekiel Elliott 1,434
2017 Kareem Hunt 1,327
2016 Ezekiel Elliott 1,631
2015 Adrian Peterson 1,485

NFL betting odds pages

Regular-season rushing yards FAQs

When will the NFL regular season rushing leader be decided?

At the conclusion of Week 18 of the regular season, the player with the most rushing yards through the season will be determined as the rushing leader.

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