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Real-world results are becoming more and more significant gather up all of our NFL predictions for Week 3 based on the odds from our best NFL betting sites.

There's a canyon-sized difference between an 0-2 start and 0-3 in the NFL. Similarly, getting to 3-0 can push aside doubts surrounding a 2-0 record. In Week 3, nine teams are looking to get to 3-0 while another nine are at risk of falling to that 0-3 mark.

Week 3 started with a lopsided matchup between the host San Francisco 49ers and the New York Giants on Thursday Night Football. Our second-to-last full slate of games before byes start in Week 5 will conclude with another Monday Night Football doubleheader with the Philadelphia Eagles visiting the Tampa Bay Buccaneers and Los Angeles Rams traveling to face the Cincinnati Bengals.

Here are our betting experts' best predictions for the two Monday Night Football games based on the NFL Week 3 odds.

NFL picks and predictions for Week 3

NFL Week 3 predictions: Monday

Eagles vs. Buccaneers pick: +5 (-110 via DraftKingsCaesarsbet365) ⭐⭐⭐⭐

Eagles-Buccaneers pick made by Mike Spector

Rams vs. Bengals pick: Under 44 (-110 via BetMGMbet365) ⭐⭐⭐⭐

Rams-Bengals pick made by Mike Spector

NFL Week 3 expert picks

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NFL betting odds pages

Check out our best NFL betting sites:

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* Bonuses not applicable in Ontario.

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