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The New England Patriots and Indianapolis Colts go head-to-head in Germany on Sunday, and we have you covered with our top Colts vs. Patriots predictions for the Week 10 showdown. We search for the best NFL odds from our best sports betting apps when making our  NFL picks.

If rumors are true, New England Patriots head coach Bill Bill Belichick is on the hot seat. Since Tom Brady left the franchise in 2020, New England has encountered various struggles. The latest was a 20-17 home loss to a Washington Commanders team that had just traded away two of its top defensive linemen.

The Patriots enjoy a considerable fan following in Germany, with a particularly significant presence in Frankfurt. The team's popularity is accentuated by the influence of Sebastian Vollmer, a former Patriots player who won two Super Bowls with Coach Belichick. Vollmer's prominence is evident as his image is prominently displayed throughout Frankfurt this week, underscoring the enduring impact of the Patriots and their key figures on the international stage, particularly in Germany where Vollmer remains a notable figure for fans of the NFL.

With a crowd north of 50,000, can the Patriots take advantage of their expected strong fan support on Sunday?

Check out our NFL Week 10 predictions and Week 10 best bets, along with our Week 10 NFL props to accompany our best Colts vs. Patriots prediction (odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).

Colts vs. Patriots prediction

Under 43.5 points (-115 via FanDuel) ⭐⭐⭐⭐

Travel is a huge factor in these international games. Even with extra sleep, the Miami Dolphins’ electric offense struggled to score points in Germany last week. 

All four international games this season, including three in London, have failed to hit the Over on the closing total. 

The Patriots are averaging 15 points per game this season, while the Colts are scoring 25.8 points per contest. Those marks combined take us Under the total set for this matchup. 

New England has had an average time of possession of 26:30 this season, which ranks last in the NFL. Last season, the lowest average time of possession by any team for the whole season was 28:20 (Carolina Panthers). The Colts’ defense has forced 33 different non-kneel down rushes to go for negative yards this season, which leads the NFL. If New England can’t get anything going on the ground, it’s going to struggle to do anything in this game.   

Last season, the Patriots scored a 26-3 win over the Colts despite having only 203 yards of offense, their fewest net yards in a win by at least 20 points in team history. Sunday’s game might not be a classic.

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Colts vs. Patriots best odds

FanDuel (-115)

DraftKingsFanDuelBetMGMCaesarsbet365
Under 43 pointsUnder 43.5 pointsUnder 43 pointsUnder 43 pointsUnder 43 points
-112-115-110-110-110

The Patriots are struggling to score points. Mac Jones has thrown 10 touchdowns and nine interceptions this season. Colts quarterback Gardner Minshew is also prone to turnovers, having thrown five interceptions in their three straight losses last month.

Until Thursday, our best NFL betting sites had the total set at 43.5. The majority have dropped it to 43, but FanDuel gives us that extra half-point. That’s the play we will take, even with slightly smaller odds. 

Colts vs. Patriots odds

Colts vs. Patriots odds analysis

The Patriots are 2-point underdogs in this contest at DraftKings. Our other main books have the spread at 1.5 points. The Pats are 2-7 against the spread this season. The Colts are 5-4 ATS this year and have covered three out of four games on the road.

The New England Patriots are 1-5 straight up this season as underdogs, while the Colts are 1-0 SU this season as favorites.

Colts vs. Patriots game info

  • When: Sunday, Nov. 12 at 9:30 a.m. ET
  • Where: Deutsche Bank Park, Frankfurt, Germany
  • How to watch: NFL Network 
  • Weather: 45 degrees, 9% chance of precipitation, 4 mph winds

Colts-Patriots prediction made 11/09/2023 at 3 p.m. ET

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