NFL Week 5 Predictions: Picks & Odds for Marquee Games

Four teams are on bye this week, knocking us down to a 14-game slate for our NFL Week 5 predictions.

Esten McLaren

Last Updated: October 7, 2024 11:02 AM EDT • 3 minute read

Kansas City Chiefs wide receiver Xavier Worthy hangs on to a touchdown pass as we look at our NFL Week 5 predicitons. — Kansas City Chiefs wide receiver Xavier Worthy hangs on to a touchdown pass. Photo Credit: Jayne Kamin-Oncea-Imagn Images.

The Super Bowl odds continue to move every week, and the 14-game Week 5 slate featured several highly impactful matchups.

The Kansas City Chiefs remain undefeated and the Super Bowl favorites. The Baltimore Ravens climbed the rankings with Sunday's win over the rival Cincinnati Bengals, and the Minnesota Vikings are the most surprising 5-0 team as we cross over the season's quarter-pole.

C Jackson Cowart looks ahead with his NFL Week 6 early picks.

NFL picks & predictions Week 5

Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Saints vs. Chiefs early picks (MNF)

Saints vs. Chiefs prediction
Saints vs. Chiefs MNF player prop bets
Saints vs. Chiefs MNF parlay
Patrick Mahomes MNF player prop bets
Travis Kelce player props
First touchdown scorer predictions for MNF
Anytime touchdown scorer predictions for MNF

Don't miss the rest of our Week 5 NFL picks. Listed odds for all games via bet365 unless stated otherwise.

Bet $5, Get $150 in Bonus Bets Win or Lose*

*Deposit required. Mobile app only. Bonus Bets wager excluded from returns. T&Cs, time limits and exclusions apply. Gambling problem? Call 1-800-GAMBLER

Claim Now

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.

NFL odds for Monday

Saints vs. Chiefs odds

Prediction: Saints +5.5 (-105 via FanDuel) vs. Chiefs ⭐⭐⭐⭐⭐

Bet $5, Win $200 in Bonus Bets

New customers only. Min. deposit $5+. Bet $5+ and win $200 in Bonus Bets, if your bet wins (within 72 hours).

Claim $200

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.

Pick made by Mike Spector.

When: Monday, Oct. 7 - 8:15 p.m. ET
Where: GEHA Field at Arrowfield Stadium, Kansas City
How to watch: ESPN
Moneyline: Saints +200 | Chiefs -245
Spread: Saints +5.5 (-110) | Chiefs -5.5 (-110)
Total: 42.5 (-110/-110)

NFL picks roundup: Week 5

NFL betting odds pages

Super Bowl Odds	NFL MVP Odds	NFL Offensive Player of the Year Odds
NFL Defensive Player of the Year Odds	NFL Offensive Rookie of the Year Odds	NFL Defensive Rookie of the Year Odds
NFL Coach of the Year Odds	NFL Comeback Player of the Year Odds	NFL Win Totals Odds
NFL Playoff Odds	NFL Draft Odds

Here are our best NFL betting sites:

Caesars Promo Code: SBRBONUSDYW | Read our Caesars Review
BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
bet365 Bonus Code: SBRBONUS | Read our bet365 Review
FanDuel Promo Code | Read our FanDuel Review
DraftKings Promo Code | Read our DraftKings Review

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.

Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)

Written by:
Esten McLaren

Esten is the Senior Publishing Editor for SportsbookReview.com. He has been in the sports betting industry since the legalization of mobile sports betting in New Jersey, and with SportsbookReview prior to the launch of sports betting in Ontario. Esten's previous stops include the USA TODAY network, including GolfWeek. He previously worked in the fantasy sports industry, with FNTSY Sports Network, theScore, and USA TODAY. Esten graduated from the College of Sports Media with a diploma in Radio and Television Sports Broadcasting after acquiring a degree in Biological Sciences from the University of Guelph. He has appeared on FNTSY Sports Network, VSiN, and VSiN's Long Shots podcast, where he correctly called Will Zalatoris as the winner of the 2022 FedEx St. Jude Championship. Esten is a big proponent of the entertainment side of sports betting and loves to dip his toes into the novelty and alt-markets while chasing long shots with reduced wagers on golf outrights and futures markets. He's also been known to sprinkle some lunch money on touchdown-scorer parlays with two notable hits still funding his bankroll. Esten looks at sports betting much like golf and advises beginner bettors to compete against themselves rather than being concerned with what others may or may not be doing based on social media claims.