NFL Odds Week 15: Lines & Spreads for Every Game

NFL odds and Week 15 lines & spreads have been posted at several of our best sportsbooks, and we're taking a look at the opening odds for the games.
Arizona Cardinals linebacker Mack Wilson Sr. breaks up the pass for Minnesota Vikings running back Aaron Jones as we look at the best NFL odds Week 15.
Arizona Cardinals linebacker Mack Wilson Sr. breaks up the pass for Minnesota Vikings running back Aaron Jones. Photo by Jeffrey Becker / Imagn Images.

2024 NFL Odds Week 15

(Odds via bet365)

Game Spread (Dec. 13) Moneyline (Dec. 13) Over/Under (Dec. 13)
Ravens vs. Giants Giants +16.5 Giants +900 42.5 (-110/-110)
Bengals vs. Titans Titans +5 Titans +190 46.5 (-110/-110)
Cowboys vs. Panthers Panthers -2.5 Panthers -150 43 (-110/-110)
Chiefs vs. Browns Browns +4 Browns +180 43 (-110/-110)
Dolphins vs. Texans Texans -3 Texans -150 46.5 (-110/-110)
Jets vs. Jaguars Jaguars +3.5 Jaguars +145 40.5 (-110/-110)
Commanders vs. Saints Saints +7.5 Saints +300 43.5 (-110/-110)
Bills vs. Lions Lions -2.5 Lions -140 54.5 (-110/-110)
Colts vs. Broncos Broncos -4.5 Broncos -220 44.5 (-110/-110)
Patriots vs. Cardinals Cardinals -6 Cardinals -260 46 (-110/-110)
Steelers vs. Eagles Eagles -5.5 Eagles -260 43 (-110/-110)
Buccaneers vs. Chargers Chargers -3 Chargers -150 45.5 (-110/-110)
Packers vs. Seahawks Seahawks +2.5 Seahawks +125 46 (-110/-110)
Bears vs. Vikings  Vikings -7 Vikings -310 44 (-110/-110)
Falcons vs. Raiders Raiders +4 Raiders +175 44.5 (-110/-110)

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The Week 15 NFL odds are out, and we have the first of four full slates to close out the season. Our NFL betting sites will have a busy week ahead reacting to betting patters and injury news that comes up throughout the week.

  • The Thursday Night Football odds opened with a Los Angeles Rams victory of the San Francisco 49ers, 12-6
  • The Sunday Night Football odds have the Packers as 2.5-point road favorites over the Seahawks in a game with major NFC playoff implications (8:20 p.m. ET, NBC/Peacock)
  • The Monday Night Football odds have a doubleheader
    • The Bears are nearly a full touchdown underdogs at the Vikings in an NFC North rivalry game (8 p.m. ET, ABC/ESPN+)
    • The Falcons' NFL playoff odds might be on the line as they look to snap a four-game losing skid when they visit the Raiders (8:30 p.m. ET, ESPN)
  • ATS leaders heading into Week 15: Steelers (10-3), Broncos (10-3), Lions (9-4), Chargers (9-4)
  • ATS losers heading into Week 15: Titans (2-11), Giants (4-9), Browns (4-9), Jets (4-9), Cowboys (4-9)
  • Over leaders heading into Week 15: Ravens (10-3), Panthers (9-4), Commanders (9-4), Bengals (9-4)
  • Under leaders heading into Week 15: Texans (4-9), Chargers (4-9), Giants (4-9)

Packers vs. Seahawks: Sunday Night Football 

  • Opening spread (Dec. 4): Seahawks +3
  • Opening moneyline (Dec. 4): Seahawks +130
  • Opening total (Dec. 4): Over/Under 46.5 (-110/-110)
  • Kickoff: 8:20 p.m. ET from Lumen Field (Seattle)
  • How to watch: NBC/Peacock

Bears vs. Vikings: Monday Night Football

  • Opening spread (Dec. 4): Vikings -5.5
  • Opening moneyline (Dec. 4): Vikings -245
  • Opening total (Dec. 4): Over/Under 42.5 (-110/-110)
  • Kickoff: 8 p.m. ET from U.S. Bank Stadium (Minneapolis)
  • How to watch: ABC/ESPN+

Falcons vs. Raiders: Monday Night Football

  • Opening spread (Dec. 4): Raiders +3
  • Opening moneyline (Dec. 4): Raiders +150
  • Opening total (Dec. 4): Over/Under 44.5 (-110/-110)
  • Kickoff: 8:30 p.m. ET from Allegiant Stadium (Las Vegas)
  • How to watch: ESPN

NFL Week 15 odds and lines

There's an advantage to betting the early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your NFL picks, the harder it becomes to identify edges and secure the best price on most sides or totals.

That's why it's important to start monitoring the NFL opening odds each week as soon as possible. A proactive approach is the first step to long-term success.

NFL betting odds pages

Here are our best NFL betting sites:

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