NFL Week 4 Predictions: Picks & Odds for Marquee Games

Week 4 is our last week before byes begin. The 16-game slate will conclude with another doubleheader of the Monday Night Football odds.

The week concludes with the Miami Dolphins hosting the Tennessee Titans at Hard Rock Stadium, and the Detroit Lions welcoming the Seattle Seahawks to Ford Field. Both home teams are short favorites.

Our C Jackson Cowart broke down all of the Super Bowl odds movement from Week 4's Sunday slate. The Kansas City Chiefs remain the consensus Super Bowl odds favorites despite another narrow victory.

We're already looking ahead to the NFL Week 5 odds with the help of Mike Spector's Buccaneers vs. Falcons early picks for Thursday Night Football.

NFL picks & predictions Week 4

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• Titans vs. Dolphins early picks
• Titans vs. Dolphins prediction
• Titans vs. Dolphins player props
• Titans vs. Dolphins MNF parlay
• Tyreek Hill MNF player prop bets
• Seahawks vs. Lions early picks
• Seahawks vs. Lions prediction
• Seahawks vs. Lions player props
• Seahawks vs. Lions MNF parlay
• First touchdown scorer predictions for Monday Night Football

Don't miss the rest of our Week 4 NFL picks. Listed odds for all games via bet365 unless stated otherwise.

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NFL odds for Monday

Titans vs. Dolphins odds

Prediction: Dolphins -1.5 (-108 via DraftKings) vs. Titans ⭐⭐⭐⭐

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Pick made by Mike Spector.

• When: Monday, Sept. 30 - 7:30 p.m. ET
• Where: Hard Rock Stadium, Miami Gardens, Fla.
• How to watch: ESPN
• Moneyline: Titans -110 | Dolphins -110
• Spread: Titans -1 (-105) | Dolphins +1 (-115)
• Total: 37 (-110/-110)

Seahawks vs. Lions odds

Prediction: Jaxon Smith-Njigba Over 47.5 receiving yards (-114 via FanDuel) ⭐⭐⭐⭐

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Pick made by Mike Spector.

• When: Monday, Sept. 30 - 8:15 p.m. ET
• Where: Ford Field, Detroit
• How to watch: ABC
• Moneyline: Seahawks +175 | Lions -210
• Spread: Seahawks +4 (-110) | Lions -4 (-110)
• Total: 46.5 (-110/-110)

NFL picks roundup: Week 4

• Anytime touchdown scorer predictions
• Touchdown parlay Week 4
• NFL survivor picks
• NFL ATS picks Week 4
• NFL upset picks Week 4
• NFL predictions & best bets Week 4
• NFL parlay picks Week 4
• NFL player props Week 4

NFL betting odds pages

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• DraftKings Promo Code | Read our DraftKings Review

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