NFL Week 17 Predictions 2024: Picks & Odds for Marquee Games

We're breaking down the latest Week 17 odds as we look ahead to Sunday and Monday's games.

Last updated: December 29, 2024 1:31 AM EST • 3 min read

Washington Commanders quarterback Jayden Daniels runs the ball against the Philadelphia Eagles as we offer our NFL Week 17 predictions. — Washington Commanders quarterback Jayden Daniels runs the ball against the Philadelphia Eagles. Photo by Peter Casey via Imagn Images

With just two weeks left in the NFL regular season, we'll be treated to five days of football this week as we offer our NFL Week 17 odds and predictions. The week began with a Christmas Day doubleheader on Netflix featuring Chiefs vs. Steelers (1 p.m. ET) and Ravens vs. Texans (4:30 p.m. ET).

We then turned our attention to the Thursday Night Football odds for the Seahawks vs. Bears, which quickly turned into a defensive slugfest.

After Saturday's three games - in which the Los Angeles Rams pushed closer to a playoff spot, the Los Angeles Chargers punched their postseason ticket, and the Cincinnati Bengals kept their hopes alive with a crucial victory over the visiting Denver Broncos - we were treated to a Sunday spread of blowouts that had major implications for fantasy football owners worldwide.

The Sunday Night Football odds featured the Falcons and Commanders, while the week wraps up in San Francisco when the Detroit Lions play the 49ers, as seen in the Monday Night Football odds.

NFL picks & predictions Week 17

Lions vs. 49ers early picks (MNF)

Don't miss the rest of our Week 17 NFL picks. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

NFL odds & predictions for Monday Night Football

Live NFL odds via our best NFL betting sites. Follow the latest NFL scores for line history and matchup info.

Lions vs. 49ers odds

Prediction: Brock Purdy Over 20.5 completions (-114 via FanDuel) ⭐⭐⭐⭐

Pick made by Mike Spector.

When: Monday, Dec. 30 - 8:15 p.m. ET
Where: Levi's Stadium (Santa Clara, Calif.)
How to watch: ABC/ESPN

NFL picks roundup: Week 17

NFL betting odds pages

Super Bowl Odds	NFL MVP Odds	NFL Offensive Player of the Year Odds
NFL Defensive Player of the Year Odds	NFL Offensive Rookie of the Year Odds	NFL Defensive Rookie of the Year Odds
NFL Coach of the Year Odds	NFL Comeback Player of the Year Odds	NFL Win Totals Odds
NFL Playoff Odds	NFL Draft Odds

Here are our best NFL betting sites:

Caesars Promo Code: SBRBONUSDYW | Read our Caesars Review
BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
bet365 Bonus Code: SBRBONUS | Read our bet365 Review
FanDuel Promo Code | Read our FanDuel Review
DraftKings Promo Code | Read our DraftKings Review

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.

Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)

Written By:
C Jackson Cowart

C Jackson Cowart is a publishing editor and lead writer for Sportsbook Review. An award-winning writer, reporter, and editor with a decade of sports media experience, "C-Jax" has worked with ESPN, Forbes, theScore, and various daily newspapers before joining the Sportsbook Review team. He's a proud graduate of the University of North Carolina, where he served as a beat writer for the Tar Heels' championship run through the NCAA men's basketball tournament in 2017. Jackson has spent the last five years covering sports betting as a predictive analyst, features writer, and industry reporter. Since joining the team in 2023, he's played a key role in Sportsbook Review's coverage of the Super Bowl, March Madness, and NBA playoffs while serving as the lead writer for the growing WNBA and NASCAR betting scenes. Though he's cashed some big bets over the years -- including Lamar Jackson to win MVP (twice) -- he's still haunted by enough second-place bet slips to wallpaper his home office. While Jackson is a committed "process over results" bettor with a keen eye for advanced stats and subtle bias in futures markets, he also embraces sports betting as a vehicle for entertainment and personal investment. He's written about everything from hot dogs to groundhogs and still hasn't forgiven his "inside source" for a sabotaged bet on the Gatorade color in Super Bowl LV.