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Justin Jefferson #18 of the Minnesota Vikings catches a pass against Cameron Sutton #1 and Kerby Joseph #31 of the Detroit Lions during the fourth quarter at U.S. Bank Stadium on December 24, 2023 in Minneapolis, Minnesota. Photo by David Berding/Getty Images via AFP.

The penultimate week of the NFL season will have a single game played Saturday before a 14-game Sunday slate and we're rounding up all of our best NFL predictions for Week 17 based on the top NFL odds.

Playoff positioning will be main topic of discussion around this week's 16-game NFL slate. Seven teams have already secured their postseason berth but only the Detroit Lions and San Francisco 49ers have wrapped up a division title.

This adds plenty of excitement to several matchups on the Week 17 slate that may be considered a little lackluster otherwise. Be sure to monitor the Super Bowl odds and NFL MVP odds throughout the week.

Read on as we round up all of our NFL predictions for Week 17 to help you get the better of the NFL Week 17 odds from our best NFL betting sites.

NFL picks and predictions for Week 17

NFL predictions Week 17: Sunday Night Football

Packers vs. Vikings pick: Ty Chandler Under 62.5 rushing yards (-110 via bet365) ⭐⭐⭐

Packers-Vikings pick made by Andrew Brennan

NFL expert picks Week 17

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NFL betting odds pages

Check out our best NFL betting sites:

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