Bills vs. Rams Touchdown Scorer Picks: MNF Week 5 Anytime TD Predictions
Last Updated: October 12, 2026 1:47 PM EDT • 2 minute read X Social Google News Link
Below, I highlight my best Bills vs. Rams touchdown scorer picks for Monday Night Football, focusing on Puka Nacua and Khalil Shakir in deceptively good matchups. Neither player has found the end zone this season, but I explain why both will tonight and why one of them could score twice.
Tonight's 8:15 p.m. ET game at SoFi Stadium in Inglewood, Calif., will air on ESPN and ABC and stream on ESPN Unlimited. The Rams are a 3.5-point betting favorite.
Bills vs. Rams touchdown scorer picks: MNF Week 5
See the latest NFL player prop odds and all of our NFL picks for Monday Night Football.
| Touchdown picks | Odds | Bet size |
|---|---|---|
| Puka Nacua, WR, Rams: To score anytime touchdown | To score anytime TD (-120 via FanDuel) | 2 units |
| Khalil Shakir, WR, Bills: To score 2+ touchdowns | To score 2+ touchdowns (+2200 via bet365) | 0.5 units |
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Bills vs. Rams touchdown scorer predictions
Best TD pick: Puka Nacua to score anytime touchdown (-120 via FanDuel)
Nacua hasn't scored a touchdown this season, but he's also only played two games. In those two contests, he has 14 receptions, 21 targets, and 199 yards.
Tonight, he faces a Bills defense that has struggled against the pass. The Bills rank 30th in passing yards allowed per game, and despite playing one fewer game than almost every team in the NFL, the Bills enter Monday Night Football allowing the sixth-most passing touchdowns.
Additionally, the Bills have struggled with true No. 1 receivers, allowing one touchdown to Nico Collins and two to Amon-Ra St. Brown. They also allowed two to Romeo Doubs last week.
📡 SBR Edge - Opportunities abound
The Rams are the most pass-happy team in the league, averaging more than 41 attempts per game. Stafford has two multi-touchdown games this season.
Long-shot TD pick: Khalil Shakir to score 2+ touchdowns (+2200 via bet365)
Shakir hasn't scored yet this season, but he's coming off a seven-catch, 82-yard performance against the Patriots. Though he's fourth on the Bills in receiving yards, he's only 41 yards behind Keon Coleman, who is second on the team. He's also tied for the team lead with 15 receptions.
Over the last two weeks, it's not No. 1 receivers who have burned the Rams but rather less popular options. Last week, the Rams allowed the Eagles' Darius Cooper to score twice, and the week before, Pat Bryant found the end zone for the Broncos.
Bills vs. Rams touchdown scorer odds: MNF Week 5
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