Ravens vs. Bills Prediction, Sunday Night Football Picks & Odds: SNF

Mark Andrews scoring features prominently in our Ravens vs. Bills prediction, along with Baltimore winning.

Mike Spector

Last Updated: September 6, 2025 11:10 AM EDT • 5 minute read

Pictured: Baltimore Ravens tight end Mark Andrews against Pittsburgh Steelers runs down the field as we look at our Ravens vs. Bills prediction. Photo by Tommy Gilligan / Imagn.

It doesn’t get much better than a Sunday Night Football matchup between two of the top favorites to win the AFC to start the season as the Buffalo Bills and Baltimore Ravens meet for the first time since last year’s playoff game, and I break it down with my Ravens vs. Bills prediction as part of our NFL picks.

This line has jumped the fence to Ravens -1 in the Sunday Night Football odds. That's led to me differing from my Early Ravens vs. Bills prediction.

Kickoff from Highmark Stadium in Orchard Park is set for 8:20 p.m. ET. In addition to my best ATS wager, I'm backing a sentimental player prop for a tight end who endured a game to forget in the last edition of this rivalry as one of our NFL predictions for Week 1.

🏈 Ravens vs. Bills picks for Sunday Night Football

NFL picks based on the odds from our best NFL betting sites. Odds subject to change.

Against the spread pick: Ravens -1 (-105 via BetMGM) vs. Bills ⭐⭐⭐⭐
Player prop: Mark Andrews to score a touchdown (+175 via DraftKings) ⭐⭐⭐⭐

Best Ravens vs. Bills against the spread prediction for Sunday Night Football

🐦‍⬛ Ravens to cover the spread: -1 (-105) ⭐⭐⭐⭐

Best odds: -105 via BetMGM | Implied probability: 51.22%

It likely took a lot of support from both the public and sharps to move this line enough to make the top Super Bowl odds contenders a home underdog in Week 1. But even though Josh Allen is 3-2 in his career against Lamar Jackson, the latter has won two of the three regular-season meetings. That has me backing Baltimore’s low point spread as my best Ravens vs. Bills prediction.

The Ravens are the most balanced squad in the league. Baltimore is coming off a season when it was the first team in the Super Bowl era with 30-plus passing touchdowns and 30-plus rushing touchdowns.

Baltimore’s improvements defensively toward the end of last season have led to me backing the team confidently this week. The Ravens led the NFL in defensive efficiency over the final eight weeks of the regular season, allowing an NFL-low 15.4 points per game and 4.4 yards per play. Baltimore also fielded a stout run defense all campaign, allowing an NFL-low 3.6 yards per rush.

The Ravens may be the only club leaguewide that can make Buffalo truly one-dimensional. They've also put together perhaps the only defense that can consistently pressure the reigning MVP. Allen was sacked the fewest times (14) among quarterbacks who made at least 12 starts last year, but Baltimore’s 54 sacks were the second-most in the NFL.

The Ravens have moved to as high as -1.5 at several of the best sports betting sites. I'm therefore squeezing every bit of value out of BetMGM’s -1 spread, which would translate to $9.52 in profit on a winning $10 wager, with a 51.22% implied probability.

Best Ravens vs. Bills player prop for Sunday Night Football

Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

🔥 Mark Andrews anytime touchdown scorer (+175) ⭐⭐⭐⭐

Best odds: +175 via DraftKings | Implied probability: 36.36%

Mark Andrews was unfairly labeled as the scapegoat after the Ravens lost their divisional-round matchup to the Bills last season when he dropped the potential game-tying two-point conversion attempt late. But there's a lot of data supporting my best Ravens vs. Bills player prop bet that he'll pick himself up and find the end zone in this rematch.

Andrews has recorded 55-plus receptions in each of his four career seasons when the tight end has played 11-plus games. Baltimore also owned the fifth-highest target rate to tight ends last season.

The Ravens enjoyed a lot of success targeting tight ends in the red zone last year. The resulting 17 touchdown receptions led the league, and were eight more than the next-closest team. Baltimore’s tight ends also ranked second in red-zone receptions (22) and red-zone targets (29).

Andrews’ implied probability to score a touchdown is as high as 40.82% through bet365’s +145 odds. But the +175 odds through DraftKings on the high end of the market return a much better value, turning a winning $10 wager into $17.50 in profit.

📊 Ravens vs. Bills odds

See all of this week's NFL odds and NFL scores.

🚑 Ravens vs. Bills injuries

Sunday Night Football game info

Matchup: Ravens vs. Bills
Kickoff: 8:20 p.m. ET
Where: Highmark Stadium (Orchard Park, N.Y.)
How to watch: NBC
Weather: 53 degrees and clear with 7-mph winds
Favorite: Ravens -1 (-105 via BetMGM)

NFL betting odds pages

Super Bowl Odds	NFL MVP Odds	NFL Offensive Player of the Year Odds
NFL Defensive Player of the Year Odds	NFL Offensive Rookie of the Year Odds	NFL Defensive Rookie of the Year Odds
NFL Coach of the Year Odds	NFL Comeback Player of the Year Odds	NFL Win Totals Odds
NFL Playoff Odds	NFL Draft Odds

❓Sunday Night Football FAQs

Who plays on Sunday Night Football?

The Baltimore Ravens and Buffalo Bills clash on Sunday Night Football in Week 1 in a rematch of last year's AFC divisional-round battle.

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Written by:
Mike Spector

Mike started in the sports writing industry in July 2019, and gained a lot of followers in his first year after finishing with the No. 2 overall record in an annual NFL betting competition, which made picks against the spread, and from an Over/Under and moneyline perspective. Mike is an avid fan of the NFL, MLB, tennis, and all college sports. In his opinion, March Madness is the best sporting event there is, and he's especially euphoric starting with conference tournament time in college basketball. Mike's a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." When making wagers, Mike leans on his NFL experience and always scours the best odds at all of the major sports betting sites, where he mostly sifts through DraftKings, FanDuel, BetMGM, and bet365. He's tried several others and is of the firm belief that bettors should not just stick to one sportsbook, as there is always likely better value to be had with the same wager. In addition, while Mike received his undergraduate degree from Villanova University, he has no issue betting against the Wildcats when it comes to college basketball wagering, and suggests other bettors should always put their “head” before their “hearts.”