Broncos vs. Bills Prediction, Picks, Odds Week 10: Monday Night Football
The Denver Broncos are in Buffalo to wrap up the NFL's Week 10 with a Monday Night Football showdown against the Bills, and we have our top Broncos vs. Bills predictions based on the best NFL odds from our best sports betting apps.
After Denver Broncos upset the Super Bowl favorite Kansas City Chiefs with a 24-9 victory in Week 8, and then enjoyed a bye in Week 9. However, they now face another tough challenge: a Monday Night Football road game against the Buffalo Bills.
In contrast to the impressive ball security of Broncos QB Russell Wilson, who has tossed just four interceptions this season, Bills quarterback Josh Allen has struggled with interceptions, throwing one in five consecutive games.
The upcoming Monday night matchup poses a key question: can the Broncos maintain their momentum and capitalize on Allen's recent challenges, or will the Bills rebound and avoid falling to a .500 record?
To accompany our Bills-Broncos player props, Josh Allen props, and Russell Wilson props, here is our best Broncos-Bills prediction for Monday Night Football (MNF odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).
Broncos vs. Bills prediction: Monday Night Football
Broncos +7.5 (-108 via DraftKings) ⭐⭐⭐⭐
If every bettor could easily forget preseason expectations, we don’t believe anyone would have the Bills favored by more than a touchdown this week. Their defense has injuries at every position, and their offense has struggled to put points on the board over the last five weeks. During that span, their average output per game is just 20.2.
Meanwhile, the Broncos avoided their letdown week by being granted a bye following their 24-9 upset win over the rival Chiefs. Though the defense is tied for last in points allowed per game, Denver's allowing just 15.0 points per game over its last three contests. That’s the second-best mark in the league for any team over their last three contests.
Both of these teams have a turnover margin of zero this season. However, those season totals don’t tell the whole story. Over the last three weeks, the Broncos are averaging a turnover margin of plus-1.0. The Bills are tied for the league’s worst turnover margin during the same span with minus-1.3.
These are two teams heading in opposite directions, and even if the Bills do pull out the win, we don’t expect them to win by more than one touchdown. Allen and the offense turn the ball over too much, and Wilson and his unit don’t.
Our Brenden Schaeffer has a more positive outlook for Bills Mafia with his Broncos vs. Bills parlay for MNF.
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Broncos vs. Bills best odds
DraftKings (-108)
DraftKings | FanDuel | BetMGM | Caesars | bet365 |
---|---|---|---|---|
+7.5 | +7 | +7.5 | +7 | +7.5 |
-108 | -105 | -110 | -110 | -110 |
DraftKings is giving us +7.5 for -108, which makes it the obvious place to wager. We love getting the extra half-point for the Broncos, so we recommend getting in now. However, keep an eye on this line throughout the week. FanDuel has the spread at -7, but with the price it's asking for the Bills, it’s clear the number is going to grow.
We expect bettors to overwhelmingly support the Bills this week. Perhaps our best sports betting apps will disregard that action, but there is a chance that the support forces oddsmakers to push this number to +8.5. At that point, you may be able to get the Broncos at +7.5 for +105 or better.
Broncos vs. Bills odds for Monday Night Football
Broncos vs. Bills odds analysis
The total opened at 46.5, and it has already gone up to 47 at both DraftKings and bet365. Despite the Under hitting in the overwhelming majority of primetime games this season, 56% of bettors are still backing the over in this game. This number could continue to climb, but we don’t think it will ever hit 48.
The Bills opened as 8.5-point favorites, but the spread has already dropped as low as seven at two of our five best sports betting sites. DraftKings, bet365, and BetMGM all have the spread sitting at 7.5. At the moment, most bettors are backing the Bills, so we don’t think this number will ever drop below the key number of 6.5.
Monday Night Football game info
- When: Monday, Nov. 13 at 8:15 p.m. ET
- Where: Highmark Stadium, Orchard Park, NY
- How to watch: ABC/ESPN
- Weather: 39 degrees, 15-mph winds, 25% chance of precipitation
Broncos vs. Bills prediction made Thursday at 1:42 p.m. ET
Broncos vs. Bills promo codes
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