Rams vs. Browns Predictions, Odds & Expert Picks: NFL Preseason Week 3

One of these teams is going to finish the preseason a perfect 3-0. Which will it be?

Matt Jacob

Last Updated: August 22, 2025 8:50 AM EDT • 4 minute read

Rams vs. Browns Predictions, Odds & Expert Picks: NFL Preseason Week 3 — Pictured: Cleveland Browns QB Joe Flacco is expected to play 20-25 snaps in the preseason finale vs. Los Angeles Rams on Saturday. Photo by Jeff Lange / USA TODAY Network via Imagn Images.

Two teams looking to cap a perfect preseason meet up at 1 p.m. ET Saturday at Huntington Bank Field in Cleveland (NFL Network, NFL+), and we’re locked and loaded with our Rams vs. Browns predictions.

NFL oddsmakers have dropped the ball so far on the Rams and Browns - both teams pulled off outright upsets in their first two exhibition contests. Those same oddsmakers are all-in on the home team in this one, as Cleveland is as high as a 7-point favorite.

When you peruse our NFL preseason Week 3 predictions, you’ll see that’s the biggest point spread on the Week 3 betting board.

🏈 Rams vs. Browns predictions & expert picks

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✅ Against the spread pick: Rams +8.5 (-105 via Caesars) ⭐⭐
✅ My best bet: Under 36.5 (-105 via Caesars) ⭐⭐⭐⭐

📖 Check out our 2025 NFL preseason betting guide for our best betting strategies and full NFL preseason schedule.

📊 Rams vs. Browns odds

Live updated odds from our best live betting sites. Follow the latest NFL scores for line history and matchup info.

🪧 Rams vs. Browns opening odds

Rams: +2.5 (-110)
Browns: -2.5 (-110)

🔮 Rams vs. Browns ATS prediction

🐏 Rams +8.5 ⭐⭐

📊 Best odds: -105 via Caesars ($10 to win $9.52)
🔢 Implied probability: 51.22%

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You have to go back to 2019 for the last time the Los Angeles Rams won a preseason finale. And that streak is likely to continue Saturday, as Los Angeles once again won’t have starting quarterback Matthew Stafford under center. Several other Rams starters are expected to see limited action at most, while Cleveland’s first-string units will play 20-25 snaps, per head coach Kevin Stefanski.

That being said, Los Angeles has covered the point spread in five consecutive preseason games - winning four of those contests outright. The only exception: a 17-15 loss at Houston as a 4-point underdog last year.

And for what it’s worth, Cleveland has ended the last three preseasons with a loss, including two defeats as a sizable favorite.

💰 Rams vs. Browns best bet

⬇️ Under 36.5 ⭐⭐⭐⭐

📊 Best odds: -105 via Caesars ($10 to win $9.52)
🔢 Implied probability: 51.22%

The Rams and Browns certainly haven’t had trouble scoring points so far in the preseason. Los Angeles has tallied 54, while Cleveland has put up 52. Collectively, the two teams have hurdled the total in three of four contests.

So why roll with the Under in this matchup - especially when it’s so low? A few reasons. First, Cleveland’s defense has been outstanding, limiting the Panthers and defending-champion Eagles to a total of 23 points (with Philadelphia mustering 88 total yards last week). And stud pass rusher Myles Garrett didn’t play in either contest, though he’ll be on the field Saturday.

L.A.’s defense hasn’t been as stout, but it held the Cowboys and Chargers to 21 and 22 points, respectively. Also, Browns starting quarterback Joe Flacco will lead the offense in the early going Saturday, but he will go against the Rams’ first-string defense.

On the other side, Rams QB Matthew Stafford is still dealing with a back injury. Stafford’s backup, Jimmy Garoppolo, also won’t play. And third-stringer Stetson Bennett, who took the bulk of the snaps in the Rams’ first two games, is giving way to fourth-stringer Dresser Winn.

🚑 Rams vs. Browns injuries

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In NFL betting, the spread is the number of points a team is favored to win or lose by. It levels the playing field for bettors by giving an advantage or disadvantage in points. Bettors win if their pick covers the spread.

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Written by:
Matt Jacob

Matt Jacob is a freelance writer and editor with more than three decades of professional experience working for an array of print and digital employers and clients. He first dove into the sports betting space in 2005 as a full-time handicapper and content producer. In addition to picking games 363 days a year, Matt wrote daily betting previews for all major professional and college sports, with those previews published (unbylined) on Yahoo’s website. He has since produced sports betting-related articles and picks pieces for outlets such as Forbes and the Philadelphia Inquirer while sharing his NFL experience. While Matt also has vast TV, radio, and webcast experience, he is perhaps the only individual in the sports betting ecosystem without a podcast (for now, anyway). Instead, Matt’s opinions and borderline unhealthy fascination with betting trends can be found on Twitter @MattRJacob. As for actual wagering, Matt believes strongly in a longstanding principle: Only bet what you can afford to lose. Because in an industry where even the best of the best succeed less than 60% of the time, you’re going to lose … a lot. And the graduate of San Diego State University - aka “The Harvard of the West” - has shoeboxes full of losing tickets to prove it.