NFL Preseason Week 2 Predictions 2025: Best Bets & Odds for Tonight

After covering each of the previous 15 games, we cap things off in Week 2 by exploring in-depth what to expect in tonight's Monday Night Football.

Gary Pearson

Last Updated: August 18, 2025 6:35 AM EDT • 2 minute read

NFL Preseason Week 2 Predictions 2025: Expert Picks, Odds for Monday Night Football — Pictured: Jayden Daniels throws a pass at training camp as we offer our NFL Preseason Week 2 Predictions 2025. Photo by Eric Canha via Imagn Images

After making our picks for the previous 15 games, we're down to Monday Night Football in our NFL preseason Week 2 predictions. The Cincinnati Bengals and Washington Commanders will battle tonight, with both starting quarterbacks expected to get some reps.

While the Bengals are the favorites across our best sports betting sites, they might have to live without All-Pro Trey Hendrickson permanently if he's dealt to another suitor.

🏈 NFL predictions for preseason Week 2

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Bengals vs. Commanders prediction

📖 Check out our 2025 NFL preseason betting guide for our best betting strategies and full NFL preseason schedule.

💰 NFL preseason odds & expert picks: Week 2

Here are the latest odds for every game via the best NFL betting sites, which update live in real time. Follow the latest NFL scores for line history and matchup info.

📊 Bengals vs. Commanders odds

Date: Monday, Aug. 18
Kickoff: 8 p.m. ET
Location: Northwest Stadium (Landover, Md.)
How to watch: ESPN, ABC

Bengals vs. Commanders prediction: Bengals first quarter ML

Best odds: +124 via Caesars

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Here's a sneak peak at why Gary Pearson expects the Bengals to surge ahead in the first quarter:

"Bengals head coach Zac Taylor confirmed Burrow and the rest of the starters will start and play for the entire first quarter.Burrow roasted the Philadelphia Eagles' defense in the opening quarter of last week's game, feasting on the defending Super Bowl champions' backups. He went 9-for-10 for 123 yards with two touchdowns in two series against Philly."

👉 Check out his full analysis in the Bengals vs. Commanders prediction.

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Written by:
Gary Pearson

Gary Pearson has written professionally since 2010, focusing on sports betting since 2014. Before entering the sports betting space, he contributed to the Canadian Press, FanSided, the Hockey Writers, the Calgary Herald, and other publications. His work and NFL experience has also been featured in Sports Illustrated and Bleacher Report. Gary, who consumes sports like a blue whale devours plankton, has a penchant for writing predictions and analyses across several sports, including hockey, soccer, football, tennis, and more. He bets regularly, preferring single-game picks, props, and live betting. While there isn't a sport he has yet to dabble in, Gary prefers betting on soccer, hockey, and football. He studied at various post-secondary institutions, including the University of Calgary, SAIT Polytechnic, and Griffith University, located in Brisbane, Australia. Gary has a marketing degree and completed his bachelor's degree in journalism at Griffith University. He feels strongly that life experience is as essential as post-secondary education, helping formulate more accurate predictions and analyses. Gary believes that competing at a high level of amateur sports during his formative years helped him better understand an athlete's psyche and the nuances and complexities of a team's dynamic, both on and off the playing surface. He feels that knowledge is immeasurably important when offering his analytical expertise. He has lived on five continents and currently resides in Canada.

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