NFL Preseason Week 1 Predictions 2025: Odds & Best Bets for Both Sunday Games
Just two games remain on the docket as we feature our NFL preseason week 1 predictions. The Miami Dolphins and Chicago Bears play in Chicago at 1 p.m. ET, while the New Orleans Saints and Los Angeles Chargers cap off proceedings at 4:05 p.m. ET from SoFi Stadium.
We have you covered for both Sunday games, offering expert picks with odds courtesy of our best sports betting sites.
๐ NFL predictions for preseason Week 1
๐ Our NFL player prop odds tool can help you find the best NFL odds to make your NFL picks across legal sportsbooks in your region.
๐ Check out our 2025 NFL preseason betting guide for our best betting strategies and full NFL preseason schedule.
๐ฐ NFL preseason odds & expert picks: Week 1
Here are the latest odds for every game via the best NFL betting sites, which update live in real time. Follow the latest NFL scores for line history and matchup info.
๐ Saints vs. Chargers odds
- Date: Sunday, Aug.โฏ10
- Kickoff: 4:05 p.m. ET
- Location: SoFi Stadium (Inglewood, Calif.)
- How to watch: NFL Network
๐ฎ Saints vs. Chargers prediction
โ Best pick: Saints -1.5 first half spread (+118 via FanDuel)
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Here's a sneak peek at why Mike Spector is predicting the Saints to cover the halftime spread.
"New Orleans will begin with Spencer Rattler under center, who started six games as a rookie last year. While Rattler failed to lead the team to a win in any of those six starts, he has reportedly shown excellent command of the offense so far in camp. I am limiting this wager to just the first half, as it is anyoneโs guess what to expect from Saints rookie quarterback Tyler Shough when he takes over. "
๐ Check out his full analysis in our Saints vs. Chargers prediction
๐ข NFL betting odds pages
โ NFL betting FAQs
What does the spread mean in betting NFL?
In NFL betting, the spread is the number of points a team is favored to win or lose by. It levels the playing field for bettors by giving an advantage or disadvantage in points. Bettors win if their pick covers the spread.
Where can I find top NFL betting odds?
Make sure you look at our top NFL betting sites to find the best odds for NFL Sunday. These sportsbooks include Caesars, BetMGM, bet365, FanDuel, and DraftKings.
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