Free NFL Picks: Predictions & Best Bets

Free picks on all NFL games for Sept. 25, 2025

Seattle Seahawks logo SEA @ Arizona Cardinals logo ARI Sep 25 | 8:15 PM ET
Rushing Yards
Kenneth Walker III logo Kenneth Walker III u52.5 Rushing Yards (-112)
Best Odds
Pick made: 9 hours ago
Matt Jacob image
Matt Jacob
Author

Kenneth Walker III went nuts in Week 2 at Pittsburgh (13 carries, 105 yards). But in his two other games against the 49ers and Saints, the Seahawks' running back turned 26 carries into just 56 total yards — that's a pathetic 2.1 yards per rush.

Arizona's defense has been stout against the run, yielding just 76.3 yards per game (fourth-best in the NFL). Bet on that front seven to shine again Thursday night and put the clamps on Walker.

Rushing Yards
Kyler Murray logo Kyler Murray o27.5 Rushing Yards (-114)
Best Odds
Pick made: 9 hours ago
Matt Jacob image
Matt Jacob
Author

Arizona QB Kyler Murray has already compiled 107 rushing yards on just 20 carries. He's been consistent, too, gaining 38, 32 and 37 yards in the first three games.

With running back James Conner (foot) done for the season, I expect Murray to be even more involved in the running game going forward. Take note, too, that Murray has hit the over on his rushing prop in five of his last six games.

Passing Yards
Sam Darnold logo Sam Darnold o219.5 Passing Yards (-115)
Best Odds
Pick made: 9 hours ago
Matt Jacob image
Matt Jacob
Author

Sam Darnold has fallen short of this passing projection in two of three games this season — barely so last week, when he had 218 yards in a rout of the Saints. Go back 11 months, though, and Seattle's quarterback has topped 230 air yards in 13 of his last 16 contests.

So I'm betting on Darnold to carve up Arizona's secondary, which has given up the third-most passing yards this season — despite facing Spencer Rattler, Bryce Young and Mac Jones.

Spread
Seattle Seahawks logo SEA +1.5 (-118)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

The Cardinals, who had the 16th-ranked offense via PFF before playing the 49ers, struggled mightily in San Francisco. They mustered 265 yards of total offense and didn't score a touchdown until midway through the fourth quarter.

Spread
Seattle Seahawks logo SEA +1.5 (-110)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Seahawks open as a 1.5-point betting favorite over the Cardinals after blowing out the Saints a week ago. Seattle feels like one of the most undervalued teams in the league in my view, and I'll gladly take the points on Mike Macdonald's bunch until the market corrects itself.

Spread
Seattle Seahawks logo SEA +1.5 (-105)
Best Odds
Pick made: 4 days ago
Dustin Saracini image
Dustin Saracini
Senior Analyst

We're giving Sam Darnold and the Seahawks the early lean here, as the defense has been pretty good through three weeks of the season. Darnold is slowly becoming the quarterback we saw in Minnesota, too.

Minnesota Vikings logo MIN @ Pittsburgh Steelers logo PIT Sep 28 | 9:30 AM ET
Receiving Yards
Jaylen Warren logo Jaylen Warren o21.5 Receiving Yards (-110)
Best Odds
Pick made: 8 hours ago
Mike Spector image
Mike Spector
Author

Through three weeks, Steelers running back Jaylen Warren leads the NFL in yards after the catch over expected and is second in missed tackles forced.

I expect Warren to again be heavily involved in Pittsburgh’s passing attack out of the backfield against a blitz-happy Brian Flores Vikings defense. 

 

MoneyLine
Pittsburgh Steelers logo PIT (+130)
Best Odds
Pick made: 11 hours ago
Mike Spector image
Mike Spector
Author

Entering last week, the Steelers defense had recorded just three sacks, allowed 149.5 rushing yards per game, and 31.5 points per game. After recording five sacks, limiting the Patriots to 119 rushing and 4.1 yards per carry, and forcing them into their first five-turnover game since 2008, the veteran group should be brimming with confidence heading overseas.

 

Spread
Pittsburgh Steelers logo PIT +2.5 (-105)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

I have enough faith in Aaron Rodgers as an underdog against a quarterback who, aside from last week's dominant display over the hapless Bengals, hasn't played meaningful football in a few years. Nothing against Carson Wentz, but playing Pittsburgh represents a sterner challenge. 

Spread
Minnesota Vikings logo MIN -1.5 (-105)
Best Odds
Pick made: 2 days ago
Philip Wood image
Philip Wood
Author

The Vikings' defense has only allowed two touchdowns in the last two weeks, and they're going to shut down an offense that managed just 203 yards against the Patriots in Week 2. As long as Carson Wentz plays a relatively clean game, the Vikings should win this comfortably.

Spread
Minnesota Vikings logo MIN -1.5 (-105)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Vikings open as a 1-point betting favorite over the Steelers in this neutral-site matchup in Dublin, Ireland. Minnesota has already signaled that Carson Wentz will start in place of J.J. McCarthy, though I care much more about the way the Vikings' defense has played of late. This feels like a rough spot for Aaron Rodgers and Co. after a narrow win last week in New England.

New Orleans Saints logo NO @ Buffalo Bills logo BUF Sep 28 | 1:00 PM ET
Spread
Buffalo Bills logo BUF -16.5 (-110)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

We're talking about a massive number here. That said, the New Orleans Saints looked like a college team in Seattle. And let's not forget that some key defensive players, along with Zach Charbonnet, didn't play for the Seahawks. I can't see things improving for the Saints against the Buffalo Bills home wagon. 

Spread
Buffalo Bills logo BUF -15.5 (-110)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Bills open as a 15.5-point betting favorite over the Saints in one of the most lopsided matchups of the 2025 NFL season. I usually shy away from laying this many points on any team, but the Bills are taking no prisoners this year as they seek to end their title drought. Godspeed, Saints bettors.

Tennessee Titans logo TEN @ Houston Texans logo HOU Sep 28 | 1:00 PM ET
MoneyLine
Houston Texans logo HOU (-335)
Best Odds
Pick made: 11 hours ago
Mike Spector image
Mike Spector
Author

The Texans had a great chance to steal a road win against the Jaguars last week, but were undone by three turnovers in the fourth quarter. Nevertheless, this line still ballooned from an opening number of 5.5 to more than a touchdown, as the Titans are amid the longest active losing streak in the NFL (nine games).

 

Spread
Houston Texans logo HOU -7.0 (-112)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

The Houston Texans' offense has been woeful. However, their defense is excellent, boasting one of the league's best pass rushes. That will be troublesome for Cam Ward on the road, who leads a Titans' offense that has been one of the worst in the league through three weeks. Houston should do just enough. 

Spread
Tennessee Titans logo TEN +7.5 (-120)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Texans open as a 7.5-point betting favorite over the Titans in an AFC South clash between two teams seeking their first win. I'm frankly shocked to see Houston laying more than a touchdown given the state of its offensive line, so I'm grabbing this number before it inevitably moves toward Tennessee.

Cleveland Browns logo CLE @ Detroit Lions logo DET Sep 28 | 1:00 PM ET
Spread
Detroit Lions logo DET -8.5 (-110)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

The Detroit Lions put on a show in Baltimore against the Ravens. Even against a defense as formidable and aggressive as the Cleveland Browns, I feel the Lions have too many weapons, especially at home. The Browns' offense will not be able to keep up. 

Spread
Detroit Lions logo DET -8.5 (-110)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Lions open as an 8.5-point betting favorite over the Browns in a rare meeting between two of the NFL's most storied (and troubled) franchises. Cleveland's defense might be the most underappreciated unit in the league, but its offense is abysmal enough to bet on a double-digit win for Detroit.

Washington Commanders logo WAS @ Atlanta Falcons logo ATL Sep 28 | 1:00 PM ET
Spread
Washington Commanders logo WAS -2.5 (-110)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

Whether Jayden Daniels plays will be crucial in deciding this spread, but I'm comfortable enough in backing the Washington Commanders even if last season's Offensive Rookie of the Year is unavailable. Atlanta's offense has been somewhat effective at home, but it's coming off a horrendous outing in Carolina. 

Spread
Atlanta Falcons logo ATL +3.0 (-115)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Commanders open as a 3-point betting favorite over the Falcons with Jayden Daniels (knee) expected to be back for Washington in Week 4. It's easy to fade the Falcons to oblivion after last week's rough outing, but Atlanta looked like a force a week earlier - I'm buying the dip on the home 'dogs.

MoneyLine
Atlanta Falcons logo ATL (+150)
Best Odds
Pick made: 7 days ago
Esten McLaren image
Esten McLaren
Content Manager

This is a very disrespectful opening number for a Falcons team that impressed on Sunday Night Football against the Vikings in Week 2. Commanders QB Jayden Daniels (knee) could be facing a multi-week absence, and the Falcons are a 5.5-point road favorite against the Panthers in Week 3. This is an early value play, as I expect Atlanta to close as the favorite.

Philadelphia Eagles logo PHI @ Tampa Bay Buccaneers logo TB Sep 28 | 1:00 PM ET
Spread
Philadelphia Eagles logo PHI -3.5 (-105)
Best Odds
Pick made: 8 hours ago
Mike Spector image
Mike Spector
Author

The Buccaneers have played with fire each week, as Baker Mayfield is now one of two quarterbacks to lead a fourth-quarter comeback in each of the first three games of a season since 1950. Now Tampa Bay has injury issues across its offensive line and will be without the services of wide receiver Mike Evans, and that has me expecting it to be dealt its first loss.

 

Spread
Philadelphia Eagles logo PHI -3.0 (-120)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

While the Philadelphia Eagles got luckier than a lotto winner last week, the Tampa Bay Buccaneers have been ravaged by the injury bug. Not only has their offensive line been impacted, but they'll also be without Mike Evans. The Eagles, meanwhile, find a way to grind out games better than any team in the league. 

Spread
Tampa Bay Buccaneers logo TB +3.0 (-110)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Eagles open as a 3-point betting favorite over the Buccaneers in a matchup between divisional winners last season. This bet is less about Philly's slow start last week and more about my belief that Tampa Bay is a tough team to close out - especially on the road following a draining win for the Eagles.

Carolina Panthers logo CAR @ New England Patriots logo NE Sep 28 | 1:00 PM ET
MoneyLine
New England Patriots logo NE (-230)
Best Odds
Pick made: 11 hours ago
Mike Spector image
Mike Spector
Author

The Panthers are coming off their first shutout victory since 2020. But perhaps we should not have been shocked by that result, as quarterback Bryce Young is now 3-1 against the Falcons and 4-23 versus all other teams.

 

Spread
New England Patriots logo NE -5.5 (-110)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

A few critical mistakes sealed the Patriots' fate against the Steelers last week. However, they played well for the most part. The Carolina Panthers have struggled on the road, and they're not good enough in the air to take advantage of the Patriots' most vulnerable defensive facet: their pass defense. 

Spread
New England Patriots logo NE -4.5 (-105)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Patriots open as a 4.5-point betting favorite over the Panthers in just their sixth meeting since the Super Bowl in 2004. Carolina is riding high after blowing out the Falcons in a game that went the Panthers' way from the jump, but they looked like the NFL's worst team before that. Don't buy it.

Los Angeles Chargers logo LAC @ New York Giants logo NYG Sep 28 | 1:00 PM ET
Spread
Los Angeles Chargers logo LAC -6.0 (-110)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

Take a moment to compare these teams' quarterbacks. The hottest ticket in the NFL right now, Justin Herbert, faces a has-been who will clearly be replaced by Jaxson Dart soon, possibly even this week. In addition, the Giants are 3-7 ATS at home in their last 10.  

Spread
Los Angeles Chargers logo LAC -5.5 (-115)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Chargers open as a 5.5-point betting favorite over the Giants in a matchup between a 3-0 contender and an 0-3 doormat. Do we know who will be under center for New York - and does it matter? Los Angeles looks like a legitimate force on both sides of the ball, and I'd expect a comfortable win at home.

Jacksonville Jaguars logo JAC @ San Francisco 49ers logo SF Sep 28 | 4:05 PM ET
Spread
Jacksonville Jaguars logo JAC +3.5 (-118)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

Brock Purdy might return to action, but the 49ers are still dealing with a rash of injuries, the lastest of which to Nick Bosa. The Jacksonville Jaguars have won two games despite their offensive inconsistencies. If they can iron out the kinks, particularly in terms of dropped passes, they should keep this one close.

Spread
Jacksonville Jaguars logo JAC +4.5 (-115)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The 49ers open as a 4.5-point betting favorite over the Jaguars after surviving the Cardinals last week en route to a 3-0 start. I'm not convinced that San Francisco is the better team in this matchup, and I keep waiting for Jacksonville to catch a break - don't be surprised if the Jags win this outright.

Indianapolis Colts logo IND @ Los Angeles Rams logo LA Sep 28 | 4:05 PM ET
Game Prop
Indianapolis Colts logo u22.5 Team Total (+100)
Best Odds
Pick made: 8 hours ago
Mike Spector image
Mike Spector
Author

The Colts are about to face a big step up in class against a Rams defense that held Saquon Barkley to 2.3 yards per rush last week, his fewest in a game with the Eagles. If Los Angeles similarly stymies the league’s leading rusher, Jonathan Taylor, I do not yet fully trust Jones to light up the scoreboard with his arm alone, especially outdoors.

Spread
Los Angeles Rams logo LA -3.5 (-110)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

This is where the Indianapolis Colts' unbeaten run ends. The Los Angeles Rams played well enough to beat the defending champs in Philly but were undone by a special teams catastrophe. Look for Sean McVay's team to rebound against Danny Dimes and Co. 

Spread
Los Angeles Rams logo LA -3.5 (-105)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Rams open as a 3.5-point betting favorite over the Colts after blowing a 19-point lead against the Eagles in Week 3. I take no pleasure in fading the undefeated Colts on a weekly basis, but this is Indy's toughest test yet against an L.A. side that will be eager to erase the bitter taste from last week's loss.

Chicago Bears logo CHI @ Las Vegas Raiders logo LV Sep 28 | 4:25 PM ET
Receiving Yards
DJ Moore logo DJ Moore o48.5 Receiving Yards (-115)
Best Odds
Pick made: 8 hours ago
Mike Spector image
Mike Spector
Author

This wager plays off fellow Bears wide receiver Rome Odunze’s success. Odunze has four touchdowns, which is tied for the most by a Bears player through the first three games of a season.

With defenses needing to pay more attention to Odunze, I expect DJ Moore to capitalize on one-on-one matchups. This is a great matchup, as the Raiders have allowed the third-most receiving yards to wide receivers this season.

 

MoneyLine
Chicago Bears logo CHI (-103)
Best Odds
Pick made: 11 hours ago
Mike Spector image
Mike Spector
Author

Pete Carroll’s teams’ success has always been predicated on running the football and playing good defense. But Raiders rookie running back Ashton Jeanty has 47 carries and none for 20-plus yards. Meanwhile, the Raiders defense just allowed 41 points to a Commanders team that had scored 39 points through the first two weeks, and was playing with a backup quarterback who hadn’t started a game since 2022.

 

Spread
Chicago Bears logo CHI +1.5 (-115)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

Did the Chicago Bears turn a corner against the Dallas Cowboys? While I won't go that far, I'm even less confident in Las Vegas after witnessing its abomination against the Jayden Daniels-less Washington Commanders. 

Spread
Chicago Bears logo CHI +1.5 (-115)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Raiders open as a 1.5-point betting favorite over the Bears in a compelling clash between 1-2 teams with new head coaches. I'm a bit surprised that Chicago isn't a consensus road favorite after a bounce-back effort for Ben Johnson and Co. last week, especially with Las Vegas looking listless for two straight weeks.

Baltimore Ravens logo BAL @ Kansas City Chiefs logo KC Sep 28 | 4:25 PM ET
Total
Baltimore Ravens logo Kansas City Chiefs logo u48.5 (-105)
Best Odds
Pick made: 8 hours ago
Mike Spector image
Mike Spector
Author

The Ravens run defense was exposed in the Week 3 loss to the Lions. Detroit’s 207 rushing yards between the tackles was the most for the Lions or against the Ravens since 2006. And Baltimore’s 224 rush yards allowed overall was the team’s most since 2017. The good news for Baltimore is that Kansas City is not built to take advantage of that weakness. 

 

Spread
Baltimore Ravens logo BAL -2.5 (-110)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

I have several concerns about Baltimore's defense without Kyle Van Noy and Nnamdi Madubuike, but Lamar Jackson is primed for a bounce-back game. The Ravens have too many offensive weapons, and as long as Derrick Henry holds onto the ball, they will be able to outscore a Chiefs offense that lacks a ground threat and has looked disjointed at times. 

Spread
Baltimore Ravens logo BAL -2.5 (-110)
Best Odds
Pick made: 2 days ago
Gary Pearson image
Gary Pearson
Publishing Editor

The Chiefs' offense is disjointed and single-dimensional. Even if Madubuike and Noy don't play, the Chiefs' offense, tied for 19th in DVOA, doesn't scare teams like it used to. Devoid of a ground attack, aside from Patrick Mahomes' scampering ability, Kansas City's offense is too predictable. 

Spread
Baltimore Ravens logo BAL -2.5 (-110)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Ravens open as a 2.5-point betting favorite over the Chiefs in a rematch of last week's Week 1 thriller at Arrowhead Stadium. Lamar Jackson has struggled to get the best of Patrick Mahomes over the years, but Baltimore looks like the best team in the NFL - that's enough for me to lay a field goal in this matchup.

Green Bay Packers logo GB @ Dallas Cowboys logo DAL Sep 28 | 8:20 PM ET
Score a Touchdown
MG Matthew Golden Score a Touchdown (Yes: +215)
Best Odds
Pick made: 8 hours ago
Mike Spector image
Mike Spector
Author

Packers wide receiver Matthew Golden has an excellent chance to score his first NFL touchdown this week. He faces a Cowboys defense that ranks 31st in yards per play allowed (6.5), and has allowed an NFL-worst 13 plays of at least 25 yards. 

In zone defense this year, the Cowboys rank 29th in completion percentage allowed (77%), last in yards per attempt (10.4), last in touchdown percentage (7.8%), and last in Total QBR (93). 

 

Spread
Green Bay Packers logo GB -6.5 (-118)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

Green Bay threw away victory in Cleveland, but it won't do the same in Dallas against one of the league's worst defenses. The Packers' defense, meanwhile, will be effective at limiting Dak Prescott, especially as CeeDee Lamb is unavailable. 

Spread
Green Bay Packers logo GB -5.5 (-115)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Packers open as a 5.5-point betting favorite over the Cowboys in Micah Parsons' return to Dallas after a blockbuster trade late last month. I don't love the number here, but I do think Green Bay is miles ahead of Dallas on the field - even after a lazy finish to last week's loss. Expect a strong response in Week 4.

Spread
Green Bay Packers logo GB -5.5 (-107)
Best Odds
Pick made: 3 days ago
Mike Spector image
Mike Spector
Author

Quarterback Jordan Love performed much better against zone than man coverage last year. That is significant since Dallas entered last week using zone on 86% of opponents’ dropbacks (the most in the NFL) while allowing 283.0 passing yards per game in that coverage.

 

Spread
Green Bay Packers logo GB -5.5 (-110)
Best Odds
Pick made: 4 days ago
Dustin Saracini image
Dustin Saracini
Senior Analyst

Green Bay's defense is just too damn good. I'll also bet the house that Micah Parsons comes away with a couple of sacks in this one. Look for the Packers to win by 10.

New York Jets logo NYJ @ Miami Dolphins logo MIA Sep 29 | 7:15 PM ET
MoneyLine
New York Jets logo NYJ (+138)
Best Odds
Pick made: 11 hours ago
Mike Spector image
Mike Spector
Author

The Dolphins allowed pressure on 49% of dropbacks last week, while Tua Tagovailoa averaged just 4.3 yards per attempt. Miami’s offense also could look rusty after a long 10-day layoff, and it is just 5-6 SU when owning a rest advantage over its opponent since 2022.

 

Spread
New York Jets logo NYJ +3.0 (-118)
Best Odds
Pick made: yesterday
Dustin Saracini image
Dustin Saracini
Senior Analyst

There's no way the Dolphins should be betting favorites in this game. The Jets almost took one away from one of the best teams in the NFL in the Bucs in Week 3, and the Dolphins backed their way into a 10-point loss on prime time against the Bills. Tyrod Taylor helps this New York offense, which is going up against a defense allowing 32 points per game - the most in the NFL.

Spread
Miami Dolphins logo MIA -2.5 (-118)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

Which winless team gets off the schneid on MNF? The New York Jets were lucky to keep things close in Tampa Bay, while the Miami Dolphins at least showed some fight in Buffalo. The Dolphins should be fresher after a more extended break, and the jury is still out on whether Justin Fields will play. Even if he does, I'm backing Miami. 

Spread
New York Jets logo NYJ +2.5 (-105)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Dolphins open as a 2.5-point betting favorite over the Jets in a prime-time battle between winless AFC East squads. Even after an inspired effort in last week's loss to the Bills, I haven't seen enough from Miami to lay points on the 'Fins as a favorite - though I'd rather bet the Under than trust either offense.

Total
New York Jets logo Miami Dolphins logo u44.5 (-110)
Best Odds
Pick made: 3 days ago
Philip Wood image
Philip Wood
Author

The Jets scored 27 in Week 3, but they only had six points entering the fourth quarter. Meanwhile, the Dolphins' passing attack is averaging just 192.0 yards per game and will struggle against a defense allowing just 207.3 air yards per contest.

Cincinnati Bengals logo CIN @ Denver Broncos logo DEN Sep 29 | 8:15 PM ET
Spread
Denver Broncos logo DEN -7.0 (-112)
Best Odds
Pick made: yesterday
Dustin Saracini image
Dustin Saracini
Senior Analyst

Jake Browning has his moments, but Week 3 was not one of them. In fact, it was an unmitigated disaster after getting blown out by the Vikings. He's about to take on an even better defense in Denver. Broncos win big.

Spread
Denver Broncos logo DEN -7.0 (-112)
Best Odds
Pick made: yesterday
Gary Pearson image
Gary Pearson
Publishing Editor

I'm all over the Broncos in this MNF tilt. Jake Browning, if he's not benched, is not the answer. Everyone, including the Bengals know that. He has thrown the most picks (5) in less than two full games. Meanwhile, the Broncos will be seething after two walk-off defeats. They'll bounce back in emphatic style. 

Spread
Cincinnati Bengals logo CIN +7.5 (-110)
Best Odds
Pick made: 2 days ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Broncos open as a 7.5-point betting favorite over the Bengals after both teams suffered tough losses last week. Cincinnati was blown out in Jake Browning's first start of the season, but we've seen him lead this offense to impressive heights before - a touchdown margin feels much too wide in this matchup.

Total
Cincinnati Bengals logo Denver Broncos logo u45.5 (-110)
Best Odds
Pick made: 3 days ago
Connor Cooper image
Connor Cooper
Author

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    • Patrick Mahomes Over/Under 2.5 touchdown passes
    • Travis Kelce anytime touchdown scorer (+110)

We advise entering the season with a couple of Super Bowl long-shot picks in your pocket. Wait for the best buy-point on the favorite(s) of your choice. You’ll be better off betting these teams following a loss than amid a winning streak. When expectations drop, that’s often the best time to find longer odds.

Once the Super Bowl comes around, treat it as any other game.

Super Bowl novelty props

Super Bowl novelty props are fun, entertainment-style wagers unique to the Super Bowl. These bet types are random, almost completely unpredictable, and may literally come down to a 50/50 coin flip. These wagers should be made with reduced investments solely for fun.

Popular novelty props:

  • Coin toss: Heads or Tails (usually -105 or -110 so that the sportsbooks take their cut, or vig)
  • Length of national anthem: Over/Under (i.e., 1 minute, 59 seconds)
  • Gatorade color poured on winning coach: Orange, Blue, Clear, etc.
  • Halftime show props: First song performed, surprise guest appearances
  • MVP speech: Will the MVP mention "teammates" or "God" first?

Some sportsbooks even offer live betting on commercials, celebrities in attendance, or camera shots during the game.

Free NFL moneyline picks

A moneyline pick is simply wagering on who will win a game - no point spreads involved. Odds show favorites with a minus (‑) and underdogs with a plus (+). Either team needs to just win by any margin to cash bets on their side.

Imagine the Bills are favorites and the Jets are underdogs:

TeamMoneyline odds
Bills–250
Jets+400
  • $100 on Bills (‑250) → Profit = $100 × (100 / 250) = $40 (total payout $140)
  • $100 on Jets (+400) → Profit = $100 × 4 = $400 (total payout $500)

Free NFL Over/Under picks

Over/Under betting doesn’t care who wins the game, just how many points are scored.

  • Book sets a line → i.e., Over/Under 54.5
  • You choose:
    • Over 54.5
    • Under 54.5
  • Odds are usually around –110, meaning you bet $110 to win $100 (and your $110 stake returns $210 total)
  • If the final score is:
    • 48–22 (total 70) → Over wins
    • 24–23 (total 47) → Under wins
  • Pushes are avoided thanks to the half-point; i.e., 54.5 guarantees Over or Under wins
    • If the total is set at 54 and that’s the exact final score, all bets on either side will be refunded (voided) as a tie
  • You can also bet on the point total in each half or quarter, or for each team

Free NFL spread picks

Our expert picks typically focus on picks against the spread as one of the most popular NFL picks. Spreads handicap matchups by setting a number teams need to cover via winning by more than that amount or losing by less than that amount.

  • The favorite is shown with a minus (–) and must win by more than the spread to cover
  • The underdog has a plus (+) and must either win outright or lose by fewer points than the spread
  • Spreads often include a .5 (i.e., 3.5) to avoid a tie or “push.” If the final margin equals the exact spread, bets are refunded as a tie
  • Key numbers such as 3, 7, and 10 are considered to represent the best bets as they represent scoring increments and you can bet on teams to win by or less than those common numbers

Free NFL prop picks

NFL player props offer the best chance to bet on your favorite (or most disliked) players. It’s also the place bettors look to attack narratives and news, and our NFL prop betting sites are generally slower to adjust these lines and odds than they are to move the game lines. Looking to back a player in a revenge game against his former team, or think your team’s WR2 will have a big day with the WR1 nursing an injury during practice? Then NFL props are for you. Rush out to these markets at your favorite sportsbook(s) whenever you see a trusted report or breaking news. We’ll also have your back by tracking that info with our NFL picks.

Betting lines are often in the form of Over/Unders for a set line of yards, pass competitions or attempts, touchdowns, or receptions/rushing attempts. Other prop bets are Yes/No bets, or just Yes bets, such as anytime touchdown scorer predictions.

Alternate lines offer the opportunity to get higher or lower odds when you’re more or less confident in the standard prop bet line. Are you convinced Patrick Mahomes will go Over his standard passing yards line of 257.5? Try betting Mahomes to finish with 280+ passing yards. Not comfortable betting Josh Allen’s Under on a line of 285.5 yards? Bet Allen to finish with 220+ passing yards, or the Under on an alternate line of 275.5 in a difficult matchup.

These alternate lines with shorter odds can be added to parlays and SGPs to boost the overall payout while maintaining a high probability of each leg hitting.

Anytime touchdown scorer props, and related markets such as first touchdown scorer, last touchdown scorer, and multiple touchdown scorer props, are among the most popular of all NFL prop picks. These can provide instant gratification with quick payouts, or offer a full-game sweat. It’s also abundantly clear when you’ve won the bet while watching the game, and you can get score notifications to your mobile device if you’re not watching RedZone.

NFL props extend beyond player props. Here are a couple examples of widely-available team and game props for every game.

Team props:

  • Eagles Over 2.5 total touchdowns (+105)
  • Jets first team to score (-110)

Game/event props:

  • Opening kickoff to be a touchback (-125)
  • Any player to score a defensive touchdown (+900)
  • Will there be a safety? Yes +750

NFL live betting

While our NFL picks coverage concludes at kickoff, live betting has become increasingly popular for fans and sportsbooks. Be sure to follow our experts on X as they offer up additional advice on the biggest games while watching along with you.

NFL live betting (also called in-game betting) lets you place wagers after the game has started, with odds that change in real time based on the game’s progress.

This allows you to react to the action and potentially find better value than pregame lines. Live betting largely negates the sportsbooks’ inherent advantage over bettors, as oddsmakers at our best live betting sites and viewers are reacting in real time to the events of any game.

Sportsbooks update spreads, totals, moneylines, and props throughout the game based on:

  • Score
  • Possession
  • Injuries
  • Time remaining
  • Player performance

Popular NFL live betting options

  • Live spread
    • Example: Chiefs -2.5 vs. Bills (after falling behind 10–0)
    • Odds might now favor the underdog if momentum shifts
  • Live total (Over/Under)
    • If the game starts slow, the total might drop from 48.5 to 42.5
    • You can bet the Over if you expect more scoring in the second half
  • Live moneyline
    • Odds on the trailing team lengthen the longer they’re behind
    • Example: Bet +250 on the Bengals to come back from a 14–3 deficit when they were +105 on the pregame moneyline
  • Next play / drive props
    • Will the next play be a run or pass?
    • Will the next drive end in a touchdown?
    • Who’ll score the next touchdown?

Strategy tips

  • Watch momentum: Injury, weather, or defensive adjustments can shift game flow
  • Shop around: Different sportsbooks may offer very different live lines depending on how their oddsmakers are reacting to the game, and where they faced a higher liability based on the pregame handle
  • Use delays wisely: Streaming delays can hurt - bet early or during timeouts if possible
  • Bet with context: Don’t chase value without understanding the matchup

How we make our NFL picks & predictions

Our No. 1 focus at Sportsbook Review is always on price shopping and finding you the best betting line and odds for each pick from our best NFL betting sites. Why should you pay more (bet shorter odds) when you can fetch a greater profit at a different sportsbook, all while needing the exact same outcome on your bet?

This is the most important part of the process for any NFL game picks, player props, and futures bets. To be a winning bettor over the long term, you simply can’t be leaving money on the table by betting shorter odds when better numbers are out there.

However, this step typically follows our experts' analysis of matchups using advanced statistics, as well as player and team performance, to determine their best bets in any given betting market. Following along with snap counts, red-zone usage, targets, and more is essential to successful NFL player prop betting. Certain matchups favor running backs over wide receivers, or slot receivers over wideouts, and we always look to who’s best equipped for success in those matchups when starting our game picks and player props.

We caution against putting too much emphasis on injuries, weather, or any narrative or news-based factor. The sportsbooks are almost always ahead of this when it comes to setting and adjusting their lines. Bettors don’t have an edge just because Patrick Mahomes won’t be playing against the Broncos on Sunday. That’s already been baked into the lines. To help with that, we look at the opening lines each week for the following week’s slate of games, and we track that movement multiple times after the lines open on the previous Wednesday. This can help you get closing line value (CLV) if the line moves too far in either direction from what oddsmakers initially made it. These early lines can help protect you from overreacting to any single wins or losses. Trust the oddsmakers.

It’s important to balance betting on favorites, underdogs, and long shots. Favorites come with shorter odds for a reason, but they don’t always win. It’s equally important to know that longer odds represent a lower probability of a winning bet. Keep a level head when assessing the weekly lines and remove personal bias from your handicapping. The general public often overreacts to any sort of injury or weather implications. Know when to be conservative and when to bet an Under or the underdog on an inflated total or spread.

Diversify your betting portfolio, manage your bankroll, and track your results.

Why trust our experts?

Sportsbook Review has been around for more than 20 years, and is a trusted source of betting picks as well as honest reviews of our best sports betting sites.

We carefully match our betting experts to the sports and topics they’re most passionate about to recommend picks they’re betting themselves. Our 1-to-5-star confidence rating is based on the matchup, their research, and the implied probability of the odds. It’s rare to see a 5-star pick on touchdown predictions, as well as futures bets, due to the inherent nature of those betting markets and the lower implied probability of the longer odds.

You’ll see many of our NFL betting experts covering the same teams or offering picks on the same markets each week as they focus on their specialties to offer trusted advice.

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