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Caleb Williams #13 of the USC Trojans looks to pass the ball as we look at our college football Week 2 predictions
Caleb Williams #13 of the USC Trojans looks to pass the ball during the first quarter against the Nevada Wolf Pack at United Airlines Field at the Los Angeles Memorial Coliseum on September 02, 2023 in Los Angeles, California. Photo by Katelyn Mulcahy/Getty Images via AFP.

The college football campaign rolls into Saturday of Week 2 and our top betting experts are back with their best NCAAF picks and predictions based on the odds from our best college football betting sites!

College football's Week 2 will roll on through Saturday following Louisville's 56-0 week-opening win over FCS Murray State on Thursday. There were two more games on Friday with Kansas and Indiana each walking away with comfortable victories.

Whether you're picking up the pieces from Week 1 (and Week 0) or looking to keep the good times rolling to start a successful season, our college football Week 2 picks and predictions are here to help.

Below, we're rounding up all of our college football betting experts' top predictions for Week 2 based on the odds from our best college football betting sites.

College football picks and predictions for Week 2

College football predictions for Saturday

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Texas vs. Alabama Under 54.5 pick (-110 via bet365) ⭐⭐⭐

Pick made by Phil Wood

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Oregon vs. Texas Tech +6.5 pick (-105 via DraftKingsBetMGM) ⭐⭐⭐

Pick made by Brenden Schaeffer

Houston vs. Rice +9.5 pick (-106 via FanDuel) ⭐⭐⭐

Pick made by Brenden Schaeffer

Wisconsin vs. Washington State +6.5 pick (-115 via FanDuel) ⭐⭐⭐

Pick made by Brenden Schaeffer

Stanford vs. USC Over 69.5 pick (-110 via FanDuel) ⭐⭐⭐

Pick made by Phil Wood

Auburn vs. Cal +6.5 pick (-110 via FanDuel) ⭐⭐⭐

Pick made by Phil Wood

College football expert picks for Week 2

College football odds pages

How to bet on college football

In the dynamic world of college football betting, success requires a blend of strategy and analysis.

First, research team statistics, recent performance, and player injuries. Identify key matchups and track trends like home-field advantage. Look beyond the headlines to assess team morale and coaching strategies.

Next, understand the point spread – it's not just about predicting the winner, but also the margin of victory. Moneyline bets focus solely on the winner, while Over/Under bets predict total points scored. Parlays combine multiple bets for bigger payouts, but are riskier. Remember, responsible bankroll management is essential – never wager more than you can afford to lose.

Lastly, stay updated with real-time odds and news as they can affect betting decisions. College football betting demands astute insight, adaptable strategies, and a disciplined approach.

Here are our best college football betting sites:

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