Ohio State vs. Indiana Expert Picks for Saturday: College Football Odds, Predictions

Our Ohio State vs. Indiana expert picks feature our college football experts with their favorite predictions for college football Saturday.
Ohio State Buckeyes quarterback Julian Sayin (10) motions as he is featured in our Ohio State vs. Indiana expert picks.
Pictured: Ohio State Buckeyes quarterback Julian Sayin (10) motions as he is featured in our Ohio State vs. Indiana expert picks. Photo by Adam Cairns/Columbus Dispatch / USA TODAY NETWORK via Imagn Images
Enjoying SBR content? Add us as a preferred source on your Google account Add as a preferred source on Google

Tomorrows showdown features one of the biggest matchups on the college football schedule, and we have you covered with our Ohio State vs. Indiana expert picks. The Ohio State Buckeyes take on the Indiana Hoosiers in a highly anticipated Big Ten showdown at Memorial Stadium in Bloomington, Indiana, with kickoff scheduled for 12 p.m. ET on FOX.


Ohio State vs. Indiana expert picks: College football Saturday

See all of our experts' college football picks for Week 7 based on the latest college football odds.

Expert Pick
Mike Spector Indiana +3.5 (-112 via DraftKings)
LJ Blut Turbo Richard anytime TD (-110 via FanDuel)
Brenden Schaeffer Julian Sayin Over 260.5 passing yards (-115 via FanDuel)

📃 Affiliate disclosure

Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)


Mike Spector's pick: Indiana +3.5 (-112 via DraftKings)

Many are writing off Indiana after an uninspiring 20-17 road win against Nebraska, in which it gained 12 fewer first downs and possessed the ball for 19 fewer minutes. But the fact that the Hoosiers could beat a 5-0 team on the road while playing poorly gives me more confidence.

Indiana is expected to have a big advantage in the trenches in this matchup. Its offense has allowed a 19% pressure rate (11th in FBS), while its defense has recorded the third-most sacks (20). 

Ohio State’s soft spot on the offensive line is at right tackle thanks to injuries, and Indiana’s dynamic 1-2 punch of edge rushers (Tobi Osunsamni and Stephen Daley) should continue to cause havoc while leading a unit that has recorded 49 tackles for loss (top three among FBS teams). 

See Mike Spector's full analysis in his Ohio State vs. Indiana prediction.

LJ Blut's pick: Turbo Richard anytime TD (-110 via FanDuel)

Turbo Richard is my top anytime touchdown scorer candidate for this Saturday's matchup against Ohio State. Richard has already recorded five touchdowns this season, proving he can contribute to his team's scoring attack. Against a tough Buckeyes defense, opportunities near the goal line could be especially valuable, and Richard has shown he can capitalize when chances come his way.

Ohio State's defense presents a difficult challenge, so finding ways to generate offense and finish drives will be critical. Richard's touchdown production makes him a player worth monitoring as his team looks to put points on the board. If the offense can establish a rhythm and create opportunities in scoring territory, Richard could be in a position to make a difference. His five touchdowns this season provide a solid foundation for backing him to find the end zone again. With another opportunity ahead this weekend, Richard is worth considering as an anytime touchdown scorer against Ohio State.

See LJ Blut's full analysis in his Ohio State vs. Indiana touchdown pick.

Brenden Schaeffer's pick: Julian Sayin Over 260.5 passing yards (-115 via FanDuel)

Julian Sayin has cleared a 261-yard passing line in four of his six games this season and faces an Indiana defense that has been better at stopping the run than slowing the opposing passing attack.

Indiana ranks 64th in FBS in pass defense, allowing 217.4 yards per game through the air. A solid comparison to what this matchup could produce in that respect was Northwestern quarterback Aidan Chiles rolling into Bloomington and posting 293 passing yards.

See Brenden Schaeffer's full analysis in his Ohio State vs. Indiana same-game parlay.


How to watch Ohio State vs. Indiana: Week 7

  • Date: Saturday, Oct. 17
  • Kickoff: 12 p.m. ET
  • Location: Memorial Stadium (Bloomington, IN.)
  • Streaming: Fox