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T.J. Watt of the Pittsburgh Steelers celebrates a sack as part of our Week 12 NFL Parlay picks and NFL predictions
T.J. Watt #90 of the Pittsburgh Steelers celebrates after recording a sack in the fourth quarter against the Cleveland Browns at Cleveland Browns Stadium on November 19, 2023 in Cleveland, Ohio. Photo by Nick Cammett/Getty Images/AFP

For our Week 12 NFL parlay predictions, we turn to the top NFL odds offered by our best sportsbooks, expecting victories from the Kansas City Chiefs and Pittsburgh Steelers on Sunday.

We’re looking to take advantage of the Kansas City Chiefs bouncing back from a disappointing loss and the Pittsburgh Steelers defense pouncing on an inexperienced backup quarterback.

We aim to include both sides in our parlay, concluding with an Under on the game total between NFC West rivals Los Angeles Rams and Arizona Cardinals, available at our best sports betting apps.

Check out our NFL Week 12 predictions and NFL Week 12 player props to accompany our best NFL parlay predictions (odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).

Best NFL parlay predictions Week 12

Steelers ML (-122) ⭐⭐⭐⭐

The loss of Cincinnati Bengals quarterback Joe Burrow to a season-ending wrist injury will surely tank the Bengals season. I’m not convinced that the Bengals offense will have any semblance of productivity with backup signal-caller Jake Browning at the helm, and the unproven backup doesn’t have a comfortable task to ease into life as an NFL starter.

The Bengals are set to face a daunting challenge from the formidable Pittsburgh pass rush, with T.J. Watt and Alex Highsmith aiming to apply intense pressure on Browning. Pittsburgh has maintained a decent .500 record, going 2-2-0 against the spread in games on the road this season. The Steelers' ability to perform well in away games suggests they might still pose a formidable threat despite playing outside their home turf.

This is exactly the type of game in which one side wins by a point with a late field goal. With FanDuel offering the Steelers ML at -120 and DraftKings at -122, we’re only paying around a dime to avoid the possibility of getting burned on a one-point win. With that value, we’re happy to roll with the security of the ML wager instead of betting Pittsburgh -1.5.

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Rams-Cardinals Under 45 (-110) ⭐⭐⭐⭐

Although the first meeting between the Arizona Cardinals and Los Angeles Rams this season came before Cardinals quarterback Kyler Murray’s return. I’m not convinced we will see a drastically different game script than the defensive struggle in the Rams' 26-9 victory.

In fact, I would project the Rams to be less productive offensively, given their recent scoring slide since that win. Los Angeles has averaged a paltry 14.25 points per game in the four weeks since its win over Arizona. Four of the Cardinals’ last six games have gone Under this total. The Rams have seen four of their last five games also end Under the total.

DraftKings offers the total at 45 instead of the more beneficial 45.5 number at FanDuel, but we’ll look at overall parlay odds to decide which lace to play this parlay.

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Chiefs -8.5 (-110) ⭐⭐⭐⭐

The Chiefs have not scored a second-half point in over a month. This is a real statistic. However, it’s one that I expect to end on Sunday afternoon in Las Vegas as the Kansas City offense lets out some pent-up aggression on an unsuspecting Raiders team that is fixing to see the helium come out of the Antonio Pierce balloon.

Kansas City’s receivers have given quarterback Patrick Mahomes plenty of nightmares this season. Still, the Chiefs may have a chance to rout the Raiders on the strength of the rushing offense as running back Isiah Pacheco looks to dice up the 27th-ranked rushing defense in the NFL. 

The Chiefs have won 10 of their last 11 against the rival Raiders, covering an 8.5-point margin in seven of those affairs. The -110 odds on this line at DraftKings help push the overall parlay odds to +563 compared to -115 on this leg and +543 overall odds at FanDuel.

NFL Week 12 parlay: +563 via DraftKings


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Week 12 NFL parlay picks made Friday at 2:30 p.m. ET

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