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The Dallas Cowboys are a gigantic home favorite over the New York Giants at AT&T Stadium, and our best Giants vs. Cowboys predictions for Week 10 are calling for a big day for Big D. We search for the best NFL odds from our best sports betting apps when making our NFL picks.

In their Week 1 encounter at MetLife Stadium, the Dallas Cowboys dominated the New York Giants with a decisive 40-0 victory, setting the tone for the Giants' challenging season. Now, with a record of 2-7, the struggling Giants are set to face the 5-3 Cowboys at AT&T Stadium, highlighting the considerable gap in performance between the two teams as they meet again in this matchup.

With New York quarterback Daniel Jones sidelined due to a knee injury, it’ll be QB Tommy Devito starting behind center against Big D. It’s a bleak outlook. The G-Men have scored a measly 16 points across the past two games when Devito has been forced into action.

Dallas is favored by 16.5 to 17.5 in this game, but should the spread be even bigger?

Check out our NFL Week 10 predictions and Week 10 best bets, along with our Week 10 NFL props to accompany our best Giants vs. Cowboys prediction and our NFL picks (odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).

Giants vs. Cowboys prediction

Cowboys -16.5 (-110 via DraftKings) ⭐⭐⭐⭐

Editor's note: This spread has now shifted to an even more gargantuan -17.5 at all of our best sports betting sites.

How are the Giants going to score in this game? They’re averaging 11.2 points per game this season, and they have scored 10 or fewer five times. DeVito went 15-of-20 for 175 yards last week, but most of that yardage came in garbage time.

The Giants’ defense has played decently of late, but they did just give up 30 points to Aidan O’Connell. Meanwhile, the Cowboys have scored 40 points twice this season, and they’ve scored 38 or more in two of their last five games. Other than a really bad performance against the Arizona Cardinals, the Cowboys have decimated bad defenses.

The Cowboys are allowing just 18.5 points per game. They also average 2.6 sacks per game, which is a number that will surely go up after facing an offensive line allowing 5.4 per contest. Simply put, if you think the Cowboys are going to score 24 points in this game, then there is almost no way they don’t cover a 16.5-point spread.

We’re tempted to play this up to -20.5. At DraftKings, that number is currently priced at +143. There is value in that play, as we don’t expect the Giants to score double-digits. And with how poorly their offense is going to move the ball, the defense is going to be exhausted and fall apart late.

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Giants vs. Cowboys best odds

DraftKings (-110)

DraftKingsFanDuelBetMGMCaesarsbet365
-16.5-17.5-16.5-17-17
-110-110-115-110-110

DraftKings and BetMGM are still offering this spread below 17, and we recommend you pounce on that number as quickly as possible. DraftKings is offering a price of -110, while BetMGM is offering -115, so the former is the better place to play right now.

We firmly believe that FanDuel is setting a trend that every single other sportsbook is bound to follow. We can’t imagine much support for the Giants this week after how they’ve looked, so if you’re on the Cowboys, you’re not going to get a better spread than this.

Giants vs. Cowboys odds

Giants vs. Cowboys analysis

The total opened at 39.5, and there has already been a bit of movement. Two of the five major sportsbooks have dropped the number to 39, while two others have dropped it to 38.5. The Cowboys have shown a few times this season that they can clear this number by themselves, but oddsmakers seem to have made up their minds about the Under.

Way back before all the injuries, the Cowboys were favored by 9.5 points. That spread is now as high as 17.5. Sportsbooks seem intent on dropping this number in favor of the Giants, but we believe all the money from the public is going to back the Cowboys no matter how big this spread gets.

Giants vs. Cowboys game info

  • When: Sunday, Nov. 12 at 4:25 p.m. ET
  • Where: AT&T Stadium, Arlington, TX
  • How to watch: FOX
  • Weather: Indoors

Giants vs. Cowboys prediction made 11/09/2023 at 10:24 a.m. ET

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