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Miles Heide #40 of the San Diego State Aztecs looks on as we make our UAB vs. San Diego State prediction for the first round of the NCAA Tournament on Friday.
Miles Heide #40 of the San Diego State Aztecs looks on against the Utah State Aggies during semifinal game of the Mountain West basketball tournament at the Thomas & Mack Center on March 15, 2024 in Las Vegas, Nevada. Photo by Ian Maule/Getty Images via AFP.

The No. 5 San Diego State Aztecs are the clear favorites against the No. 12 UAB Blazers on Friday in the opening round of East Region play in the NCAA Tournament, as we offer our UAB vs. San Diego State prediction based on the best March Madness odds.

San Diego State reached the finals of the 2023 NCAA Tournament as a No.5 seed and finds itself in familiar territory heading into the 2024 chapter of March Madness. Our best sports betting sites have SDSU set as favorites against the UAB Blazers, with things set to get underway at 1:45 p.m. ET on TNT.

Based on advanced metrics, SDSU is one of the 11 teams that will win the NCAA Tournament, but the Aztecs struggle with their offense, ranking as one of the weakest in the field. UAB and its defensive strategy could disrupt their offensive flow in the opening round.

As part of our March Madness predictions, here is our best UAB vs. San Diego State prediction and college basketball picks (odds via our best March Madness betting sites; pick confidence based on a 1-to-5-star scale).

UAB vs. San Diego State odds

UAB (12) vs. San Diego State (5) prediction: East Region 

San Diego State Under 73.5 points ⭐⭐⭐

Best odds: -114 via FanDuel

This is a tricky game to handicap, as the line has moved in favor of UAB even with KenPom calling for a 9-point win for San Diego State. I just simply don't trust the Aztecs' offense in a critical spot on Friday.

To be clear, UAB is not a good defensive team, ranking outside of the top 200 in adjusted efficiency. The Blazers don't force turnovers and allow far too many open shots along the perimeter. That can serve as a double-edged sword, though, if opponents are baited into shooting threes without the requisite shooters to capitalize.

Fittingly, San Diego State is one of the worst shooting teams in the country, ranking 307th nationally in 3-point percentage (31.3%) with the second-worst mark of any tournament team. The Aztecs are built to score inside, but they could run into issues against NBA hopeful Yaxel Lendeborg (6-foot-9, 230 pounds), who ranks in the top 30 nationally in blocks per game (2.1) and top 15 in defensive rebound rate (27.7%).

With San Diego State featuring one of the slowest tempos in the country, this team total feels a tick too high - especially if the Aztecs run cold from deep.

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UAB vs. San Diego State best odds

FanDuel (-114)

DraftKingsFanDuelBetMGMCaesarsbet365
Under 72.5Under 73.5Under 73.5Under 73.5Under 73.5
-110-114-125-115-125

All five of our best sports betting sites are offering a team total for San Diego State, and four of them are dealing that total as high as 73.5. But only one is offering that wager at -114 or better, which is why we'd recommend betting it at FanDuel.

With such a small gap between that price and the one at Caesars, for example, I'd highly recommend checking out our March Madness betting promos to get the most of our wager for this game and any other contest during the NCAA Tournament.

UAB vs. San Diego State spread & Over/Under analysis

This game has seen among the most dramatic line movement of any first-round contest, with San Diego State briefly opening as a 10.5-point favorite before settling between -7 and -7.5 across our best sportsbooks.

The total has also been on the move, touching as low as 133.5 before moving all the way up to 139.5 at BetMGM as of Tuesday evening. That number could keep rising in a game projected to reach 143 combined points, per KenPom.

UAB vs. San Diego State game info

  • When: Friday, March 22
  • Tip-off: 1:45 p.m. ET
  • Where: Spokane Veterans Memorial Arena, Spokane, Wash.
  • How to watch: TNT

UAB-San Diego State prediction made Tuesday at 7:15 p.m. ET.

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