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Pictured: Auburn's Johni Broome backs down Vanderbilt's Tyler Nickel. Photo by Steve Roberts via Imagn Images.

To nobody's surprise, Auburn and Duke remain the favorites by the Final Four odds, with the two programs seemingly being head and shoulders above everyone else this college basketball season.

Even with the Tigers and Blue Devils losing to Florida and Clemson, respectively, last week, their March Madness odds didn't budge. But will the two programs be able to survive four NCAA Tournament games and reach San Antonio?

Final Four odds

Final Four odds from our March Madness betting sites.

  • Auburn has been the most consistent team in the country thanks to Johni Broome, and Bracket Matrix projects the Tigers to earn the No. 1 overall seed in the NCAA Tournament
  • Led by Wooden Award odds favorite Cooper Flagg, the Blue Devils are easily the best team in the ACC in a down year for the conference and are positioned for a one-seed
  • Thanks to Duke's loss to Clemson, Alabama is the No. 2 team in the latest AP Top 25 Poll but has to play seven straight ranked opponents to close the regular season
  • After an inconsistent start to the season, Houston has solidified itself as the best team in the Big 12 once again, however, it's not projected to earn a No. 1 seed
  • Both Iowa State and Tennessee have both been ranked in the top two at various points this season

Final Four odds favorites 2025

Auburn Final Four odds (-120)

Auburn leads the Final Four odds.
Pictured: Auburn's Tahaad Pettiford dribbles as Ole Miss' Matthew Murrell defends. Photo by Petre Thomas via Imagn Images.

If Flagg doesn't win the Wooden, it will be Broome, who has looked as good as ever since returning from injury. Auburn has to play Alabama twice before the season ends, but the Tigers have been the best team in the best conference and have the best lineup.

Beating Alabama at least once and having a good showing in the SEC Tournament will be needed for Auburn to earn the No. 1 overall seed in the NCAA Tournament, but regardless, this is a roster talented enough to reach the Final Four. If they do, a $10 bet pays an $8.33 profit.

Best odds: -120 via BetMGM | Implied probability: 54.55%

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Duke Final Four odds (-110)

Only two teams have beaten Auburn this season, and Duke was one of them. With Flagg living up to the NBA draft odds buzz as a two-way nightmare, the Blue Devils look capable of competing with any team in the country and have a serious chance to win out and take home the ACC Tournament title with how bad the conference is this year.

While Flagg is carrying the load, this team has more than just him with fellow freshman studs Kon Knueppel and Khaman Maluach and veterans Tyrese Proctor and Sion James. Like Auburn, I have a tough time seeing Duke not push to the Final Four with how much talent they have and how better they've been than almost every other program this season.

Best odds: -110 via BetMGM | Implied probability: 52.38%

Alabama Final Four odds (+150)

The Crimson Tide are among the Final Four odds favorites.
Pictured: Alabama's Mark Sears shoots the ball against Georgia's Dakota Leffew. Photo by Will McLelland via Imagn Images.

If Auburn and Duke are the clear top two teams in the country, Alabama's got my vote for the obvious third-best program. This team made the Final Four last year relying on its explosive offense and non-existent defense, and with All-American guard Mark Sears and big man Grant Nelson, it should be able to make some serious noise again.

While Nate Oats' team has been on fire lately, I still have concerns about their style of play when their shots aren't dropping - like in the loss to Ole Miss. However, I'd wait to back them with the Crimson Tide playing Auburn twice, Florida, and Tennessee down the stretch - either these odds lengthen with loss or you can be more confident in backing Bama.

Best odds: +150 via FanDuel | Implied probability: 40%

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Houston Final Four odds (+210)

The opposite of Alabama, the Cougars once again have a suffocating defense capable of taking the air out of opposing offenses. But a slow start that included losses to Auburn and Alabama has me wondering what the Cougars ceiling can be with this style, we saw them lose in the Sweet 16 last year as a No. 1 seed with their defense-first mentality.

While I like the combo of guard L.J. Cryer and forward J'Wan Roberts as a one-two punch, Houston lacks a player capable of taking over on offense in crunch time. With a tough stretch to close the season, I'm not sure Houston will even earn a one-seed.

Best odds: +210 via FanDuel | Implied probability: 32.26%

My Final Four contender to watch

St. John's Final Four odds (+600)

St. John
Pictured: St. John's guard RJ Luis dribbles as Seton Hall guard Garwey Dual defends. Photo by Vincent Carchietta via Imagn Images.

If you love defensive basketball, instead of backing Houston at +210, why not look at St. John's and what Rick Pitino is doing in the Big East? Especially with a $10 winning bet paying a $60 profit. The Red Storm have completely turned it around in Pitino's second season as bench boss, thanks to the play of RJ Luis, Kadary Richmond, and Zuby Ejiofor.

That trio has St. John's poised to potentially earn a top three-seed, and I think they're a dark horse for a one-seed if the SEC cannibalizes itself and the Red Storm wins out. And unlike Houston, Pitino has a scorer capable of putting the team on his back when needed in Luis.

Best odds: +600 via FanDuel | Implied probability: 14.29%

Final Four odds history

Here is a look at Final Four odds history. UConn had +2000 pre-season odds last season. The year prior the Huskies had +8000 odds.

YearMarch Madness championPreseason Final Four odds
2023-24UConn+2000
2022-23UConn+8000
2021-22Kansas+1400
2020-21Baylor+800
2018-19Virginia+1350
2017-18Villanova+2700
2016-17North Carolina+1900
2015-16Villanova +2500
2014-15Duke+900
2013-14Connecticut +6500
2012-13Louisville+700

What schools have the most Final Four appearances?

SchoolFinal Four appearancesLast appearance
North Carolina212022
UCLA182021
Duke172022
Kentucky172015
Kansas152022
Michigan State102019
Ohio State102012
Indiana82002
Louisville82013
UConn72024

March Madness FAQs

Who is the 2025 Final Four odds favorite? 

Auburn is the biggest favorite to reach the Final Four in San Antonio in April. Their odds imply a 54.55% probability they'll reach the Final Four.

Where is the 2025 Final Four going to be played?

The 2025 Final Four will be played April 5 and 7 at Alamodome in San Antonio.

Who was the Final Four favorite last year?

The Huskies were the consensus betting favorites with odds as short as -455 to reach the Final Four during March Madness last year. Those odds gave the Huskies an implied probability of 81.98% of making the Final Four, according to our odds converter, before they eventually reached the semifinal and won it all.

Who was in last year's Final Four?

The UConn Huskies, Purdue Boilermakers, Alabama Crimson Tide, and NC State Wolfpack reached the Final Four of the NCAA Tournament after winning their respective regions in March Madness.  

UConn and Purdue advanced to meet in the national championship game on Monday, April 8. The Huskies won that game 75-60 to secure back-to-back titles.

Where was the Final Four played last year?

The 2024 Final Four and national championship game were held at State Farm Stadium in Phoenix, Ariz.

March Madness betting odds pages

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