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Santiago Vescovi #25 of the Tennessee Volunteers features in our March Madness prop bets.
Santiago Vescovi #25 of the Tennessee Volunteers handles the ball against Jalen Dalcourt #5 of the Louisiana Lafayette Ragin Cajuns in the first round of the NCAA Men's Basketball Tournament on March 16. Mike Ehrmann/Getty Images/AFP

The opening weekend of March Madness featured tons of excitement, but this weekend is really where things get interesting as the Final Four crystalizes. Read on for our best Sweet 16 prop bets based on top NCAAB odds.

With the Sweet 16 tipping off on Thursday afternoon, there are plenty of opportunities to cash on some prop bets this week.

Among our favorite Sweet 16 props, we’re eyeing a couple of SEC stars looking to lead their teams to deep March Madness. Plus, we’ve got a team total points prop with multiple paths to hitting for a fast-paced offense. 

Here are our best March Madness Sweet 16 prop bets (odds via BetMGM, DraftKings Sportsbook, FanDuel Sportsbook).

March Madness Sweet 16 prop bets

  • Santiago Vescovi Over 2.5 made 3-pointers (-105 via BetMGM)⭐⭐⭐⭐
  • Brandon Miller Over 26.5 points + rebounds + assists (-125 via DraftKings)⭐⭐⭐⭐
  • Team total points: Arkansas Over 68.5 (-106 via FanDuel)⭐⭐⭐⭐

March Madness prop predictions

Vescovi Over 2.5 made 3-pointers (-105 via BetMGM) ⭐⭐⭐⭐

Tennesee guard Santiago Vescovi can pour it in from deep range, averaging 2.51 3-point field goals per game this season. He’s been especially hot down the stretch of the campaign as he’s drained at least three triples in 10 of his last 12 games. 

Although he fell short recently in the Round of 64 against Louisiana, that 1-for-2 showing from deep marked Vescovi’s only game with fewer than seven 3-point attempts since mid-February.

FanDuel has three-plus Vescovi made triples at -118 odds while DraftKings offers Over 2.5 made threes at -110. BetMGM takes the cake, though, with attractive -105 odds on the Over 2.5.

Miller Over 26.5 points + rebounds + assists (-125 via DraftKings) ⭐⭐⭐⭐

After an 0-for-5 performance from the field in Alabama’s opening game of the NCAA Tournament, Brandon Miller shook the rust off in the Round of 32 by hitting five field goals. Even with that bounce-back performance, however, Miller’s line would have fallen short of this 26.5 points/rebounds/assists prop because of a goose egg on assists. 

DraftKings seems to be baiting us into this PRA Over by posting it at a 26.5 mark that Miller had attained in seven consecutive games leading up to the NCAA Tournament. 

While there’s risk in a quiet night facing a San Diego State defense that allows just 63.3 points per game, Miller is too capable of gaudy totals in any of the three categories to count him out on this combined figure.

At better odds, this would be a five-star play. At -125 it’s still a strong four-star recommendation.

Team total points: Arkansas Over 68.5 (-106 via FanDuel) ⭐⭐⭐⭐

Though UConn has not allowed an opponent to eclipse 68.5 points against it yet this month, an Arkansas side fresh off its upset of No. 1-seed Kansas could be the unit to make it happen.

The Hogs aren’t quite a Top 50 offense (51st according to KenPom) but they make the most of their constant push for points by deploying the 49th-fastest adjusted tempo in the nation. While UConn tends to prefer a slower pace, the Huskies are an offensive force (3rd in AdjO) that can adapt to a higher-scoring affair. They can let Arkansas dictate the pace and beat the Razorbacks at their own game.

I like the Hogs to get to 70 if they can pull off an upset. But even in a presumed loss for the Hogs, they could still clear this total. Play it at FanDuel where the odds are -106 instead of -110 at DraftKings.

Here are our best March Madness betting sites:

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