College Football Week 10 Predictions: Picks & Odds for Marquee Games
As a whole this week's slate isn't overly spectacular, but our Week 10 college football predictions look at the games you won't want to miss, including one of the most important matchups of the year.
- Ohio State plays Penn State in a game between two College Football Playoff odds contenders that could have major ramifications in the Big Ten
- Oregon, led by Heisman Trophy odds favorite Dillon Gabriel, heads to the Big House to take on Michigan
- At the World's Largest Outdoor Cocktail Party, college football championship odds favorite Georgia is poised to beat up on Florida
While Week 10 lacks for AP Top 25 matchups, the Buckeyes and Nittany Lions are treating us to a massive matchup on Saturday at noon ET.
College football picks & predictions Week 10
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College football odds for Saturday
College football odds via DraftKings and subject to change. Follow the latest college football scores for line history and matchup info.
Oregon vs. Michigan odds
Prediction: Oregon -14.5 (-108 via DraftKings) vs. Michigan ⭐⭐⭐⭐
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Pick made by Phil Wood.
- When: Saturday, Nov. 2 (3:30 p.m. ET)
- Where: Michigan Stadium (Ann Arbor, Mich.)
- How to watch: CBS, Paramount+
- Moneyline: Oregon (-650) | Michigan (+470)
- Spread: Oregon -15 (-110) | Michigan +15 (-110)
- Total: 45 (-112/-108)
Florida vs. Georgia odds
Prediction: Georgia -14.5 (-105 via FanDuel) vs. Florida ⭐⭐⭐
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Pick made by Shane Jackson.
- When: Saturday, Nov. 2 (3:30 p.m. ET)
- Where: EverBank Stadium (Jacksonville, Fla.)
- How to watch: ABC, ESPN+
- Moneyline: Florida (+525) | Georgia (-750)
- Spread: Florida +16.5 (-110) | Georgia -16.5 (-110)
- Total: 52 (-110/-110)
Texas Tech vs. Iowa State odds
Prediction Rocco Becht Over 254.5 passing yards (-114 via FanDuel) ⭐⭐⭐⭐⭐
Pick made by Brenden Schaeffer
- When: Saturday, Nov. 2 (3:30 p.m. ET)
- Where: Jack Trice Stadium (Ames, Iowa)
- How to watch: ESPN
- Moneyline: Texas Tech (+410) | Iowa State (-550)
- Spread: Texas Tech +14 (-112) | Iowa State -14 (-108)
- Total: 55.5 (-112/-108)
College football picks roundup: Week 10
- College football Week 10 ATS picks
- College football Week 10 upset picks
- College football Week 10 player props
- College football Week 10 expert picks
- College football Week 10 best bets
College football betting odds pages
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- FanDuel Promo Code | Read our FanDuel Review
- DraftKings Promo Code | Read our DraftKings Review
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