College Football Expert Picks Week 10: Our 12 Best Bets This Week
One of the most important games of the season takes place Saturday, and it's the highlight of our Week 10 college football expert picks.
- Ohio State takes on Penn State in a battle of top four programs that will surely have a massive impact on the college football championship odds
- The fight for the Commander-in-Chief's Trophy isn't the only reason to tune into Air Force vs. Army, with the Black Knights firmly in the Group of Five College Football Playoff odds race
- Heisman Trophy odds favorite Dillon Gabriel leads Oregon into the Big House against reigning champion Michigan
As part of our Week 10 college football predictions, our experts break down their best bets for the top games on Saturday.
College football expert picks for Week 10
College football odds as of Friday and subject to change. See all of our college football picks for more on this week's top matchups.
| Matchup | Rob Paul | C Jackson Cowart |
|---|---|---|
| Ohio State vs. Penn State | Will Howard Under 232.5 passing yards (-117 via Caesars) | Penn State +3.5 (-115 via BetMGM) |
| Air Force vs. Army | Bryson Daily 2+ touchdowns (-110 via bet365) | Army Over 31.5 points (-102 via FanDuel) |
| Oregon vs. Michigan | Dillon Gabriel Over 270.5 passing yards (-114 via FanDuel) | Oregon -14.5 (-108 via DraftKings) |
| Florida vs. Georgia | Trevor Etienne Over 79.5 rushing yards (-114 via FanDuel) | Georgia -14.5 (-110 via BetMGM) |
| Texas A&M vs. South Carolina | Le'Veon Moss Over 78.5 rushing yards (-110 via bet365) | Texas A&M -3 (-110 via bet365) |
| Louisville vs. Clemson | Cade Klubnik Over 2.5 passing touchdowns (+102 via Caesars) | Louisville +10.5 (-108 via FanDuel) |
Rob Paul's Week 10 picks
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Ohio State vs. Penn State prediction: Will Howard Under 232.5 passing yards ⭐⭐⭐⭐
Ohio State's offensive line has major issues without left tackle Josh Simmons and Penn State's pass rush should be all over Will Howard. Led by Abdul Carter, the Nittany Lions are 16th in EPA per dropback on defense.
Howard has thrown for fewer than 232.5 yards in two of his last three games. If he does again, a $10 bet pays an $8.55 profit.
I broke down this matchup further in my Ohio State vs. Penn State prediction, while Shane Jackson offered his favorite prop bets for this game in his Ohio State vs. Penn State player props.
Best odds: -117 via Caesars | Implied probability: 53.92%
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Air Force vs. Army prediction: Bryson Daily 2+ touchdowns ⭐⭐⭐⭐
Only one player in the country has more rushing touchdowns than Ashton Jeanty, and it's Army QB Bryson Daily. Daily's rushed for 19 TDs this season with two-plus in five straight games.
Air Force's defense is horrendous - 111th in EPA per rush and 98th in SP+ - and has allowed the 13th-most rushing TDs in the country (18). If Daily finds the end zone at least twice, a $10 bet pays a $9.09 profit.
Mike Spector is predicting an early score for Daily in his Air Force vs. Army prediction.
Best odds: -110 via bet365 | Implied probability: 52.38%
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Florida vs. Georgia prediction: Trevor Etienne Over 79.5 rushing yards ⭐⭐⭐⭐
Perhaps the better Etienne brother, Trevor has rushed for at least 80 yards in two of his last three games - including against a Texas defense that's No. 2 in SP+. So, running wild on a Florida defense outside the top 40 in SP+ should be easy.
With Etienne carrying the load, the Bulldogs are fourth in EPA per rush on offense and they're expected to have star guard Tate Ratledge back. If Etienne pops off at the World's Largest Outdoor Cocktail Party, a $10 bet pays an $8.77 profit.
Shane Jackson is also expecting a strong day for the Bulldogs in his Florida vs. Georgia prediction.
Best odds: -114 via FanDuel | Implied probability: 53.27%
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C Jackson Cowart's Week 10 picks
Oregon vs. Michigan prediction: Oregon -14.5 ⭐⭐⭐⭐⭐
This was priced as a field-goal affair for much of the summer, but these teams have taken wildly divergent paths to get to this point.
The Ducks have picked up steam over an 8-0 start behind the No. 2 offense by SP+, led by the Heisman favorite in Gabriel. Their defense has been a top-15 unit across the season, too, while allowing just nine points in the last two weeks combined.
Meanwhile, the Wolverines can't decide on a quarterback, and their all-world defense on paper has been exploited for weeks. This could get ugly in a hurry. Our Phil Wood agrees in his Oregon vs. Michigan prediction.
Best odds: -108 via DraftKings | Implied probability: 51.92%
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Texas A&M vs. South Carolina prediction: Texas A&M -3 ⭐⭐⭐⭐⭐
I'm buying what the Aggies are selling lately, especially if backup-turned-savior Marcel Reed gets another shot after last week's riveting second half to beat LSU.
Texas A&M is one of nine teams with a top-20 offense and defense by SP+. Its defense held LSU's offense - a top-four unit nationally - to six points after intermission, and its offense has a different element with Reed under center.
South Carolina is a frisky foe, but I'll gladly lay a field goal in this matchup with the rest of our best college football betting sites still at -3.5.
Best odds: -110 via bet365 | Implied probability: 52.38%
Louisville vs. Clemson prediction: Louisville +10.5 ⭐⭐⭐⭐⭐
It's hard not to be impressed by Clemson's six-game win streak after a discouragig season opener, but this feels like too much respect against a Louisville team that is better than its 5-3 record suggests.
All three of those losses came by exactly seven points against teams currently ranked in the top 20 (No. 5 Miami, No. 8 Notre Dame, No. 20 SMU). These two opponents are both top-25 teams by SP+, and I'd expect another nail-biter on Saturday.
Best odds: -108 via FanDuel | Implied probability: 51.92%
–– C Jackson Cowart (SBR | Twitter/X)
College football picks roundup: Week 10
- College football Week 10 ATS picks
- College football Week 10 upset picks
- College football Week 10 player props
- College football Week 10 best bets
College football betting odds pages
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