Free Expert Picks, Predictions, and Best Bets Today

Free picks on all games for Sept. 22, 2025

NFL Picks

Detroit Lions logo DET @ Baltimore Ravens logo BAL Sep 22 | 8:15 PM ET
Passing Yards
Jared Goff logo Jared Goff o260.5 Passing Yards (-114)
Best Odds
Pick made: 21 hours ago
Gary Pearson image
Gary Pearson
Publishing Editor

Based on the Ravens' aforementioned defensive absences (Noy and Madubuike), I'm confident in backing Goff to amass at least 261 passing yards. Goff hit the Over on that number in seven of the previous 10 regular-season games, including three of the last four on enemy terrain. 

Total
Detroit Lions logo Baltimore Ravens logo o52.5 (-115)
Best Odds
Pick made: 21 hours ago
Gary Pearson image
Gary Pearson
Publishing Editor

The Ravens scored the third-most points per game at home last season (31.1) and have averaged 34 per game at M&T Bank Stadium in the last eight regular-season home games. In seven of those games, they scored at least 30. 

Seattle Seahawks logo SEA @ Arizona Cardinals logo ARI Sep 25 | 8:15 PM ET
Spread
Seattle Seahawks logo SEA +1.5 (-110)
Best Odds
Pick made: 1 hours ago
C Jackson Cowart image
C Jackson Cowart
Senior Publishing Editor

The Seahawks open as a 1.5-point betting favorite over the Cardinals after blowing out the Saints a week ago. Seattle feels like one of the most undervalued teams in the league in my view, and I'll gladly take the points on Mike Macdonald's bunch until the market corrects itself.

Spread
Seattle Seahawks logo SEA +1.5 (-105)
Best Odds
Pick made: yesterday
Dustin Saracini image
Dustin Saracini
Senior Analyst

We're giving Sam Darnold and the Seahawks the early lean here, as the defense has been pretty good through three weeks of the season. Darnold is slowly becoming the quarterback we saw in Minnesota, too.

NCAAF Picks

USC Trojans logo USC @ Illinois Fighting Illini logo ILL Sep 27 | 12:00 PM ET
Spread
USC Trojans logo USC -6.5 (-110)
Best Odds
Pick made: 8 hours ago
Rob Paul image
Rob Paul
Publishing Editor

This USC team has had little hype, but it's the best one Lincoln Riley has had in some time, thanks to an offense ranked No. 4 by SP+. QB Jayden Maiava leads the country in QBR (94.3), and has so many weapons like Makai Lemon and Waymond Jordan. Meanwhile, Illinois just got embarrassed and lost by 53 to Indiana. Bouncing back from that is going to be tough for Bret Bielema's team.

Notre Dame Fighting Irish logo ND @ Arkansas Razorbacks logo ARK Sep 27 | 12:00 PM ET
Total
Notre Dame Fighting Irish logo Arkansas Razorbacks logo o64.5 (-110)
Best Odds
Pick made: 7 hours ago
Mike Spector image
Mike Spector
Author

Razorbacks quarterback Taylen Green has totaled 350-plus yards in five consecutive games. He leads all SEC quarterbacks in yards per game (387.8), in large part because he ranks third overall in the conference with 360 rushing yards. The last time the Fighting Irish faced an elite dual-threat quarterback like Green, Marcel Reed totaled 397 yards and led Texas A&M to a 41-point outburst against Notre Dame, the most scored by any team against the Fighting Irish since 2019.

 

MLB Picks

St. Louis Cardinals logo STL @ San Francisco Giants logo SF Sep 22 | 9:45 PM ET
Strikeouts Thrown
Michael McGreevy logo Michael McGreevy u3.5 Strikeouts Thrown (-115)
Best Odds
Pick made: 5 hours ago
Josh Goldberg image
Josh Goldberg
Author
Spread
San Francisco Giants logo SF -1.5 (+150)
Best Odds
Pick made: 7 hours ago
Josh Goldberg image
Josh Goldberg
Author

The Cardinals have struggled to a 32-43 record on the road this season. Justin Verlander has been much better pitching at Oracle Park, and I think the Giants match up well with Cardinals righty Michael McGreevy's pitch-to-contact style.

WNBA Picks

Our experts and prediction models are hard at work analyzing the data. Check back shortly for today’s picks.
Check our WNBA coverage, WNBA projections, WNBA odds, and WNBA Matchups

CFL Picks

Our experts and prediction models are hard at work analyzing the data. Check back shortly for today’s picks.
Check our CFL coverage, CFL projections, CFL odds, and CFL Matchups

NBA Picks

Houston Rockets logo HOU @ Oklahoma City Thunder logo OKC Oct 21 | 7:30 PM ET
Spread
Oklahoma City Thunder logo OKC -6.5 (-105)
Best Odds
Pick made: one month ago
Liam Fox image
Liam Fox
Publishing Editor

Oklahoma City will begin its first-ever title defense with a win on opening night. The Rockets may prove to be legitimate title contenders, but it will take time for them to find their groove after the addition of Kevin Durant. The Thunder set the all-time record for point differential in 2024 (averaging plus-12.87 per game), and they'll roll to a comfortable victory here.

Golden State Warriors logo GS @ Los Angeles Lakers logo LAL Oct 21 | 10:00 PM ET
Spread
Los Angeles Lakers logo LAL -3.5 (-114)
Best Odds
Pick made: one month ago
Andrew Reid image
Andrew Reid
Publishing Editor

The Lakers made some positive offseason additions, and that should only help the squad build on their 50-win season last year. LeBron and Doncic having home court advantage should be enough to help cover this short line on opening night in Los Angeles.

Total
Golden State Warriors logo Los Angeles Lakers logo o224.5 (-110)
Best Odds
Pick made: one month ago
Liam Fox image
Liam Fox
Publishing Editor

There's simply too much offensive firepower on these teams for this to be anything other than a scoring showcase on opening night. The Warriors and Lakers combined for more than 225 points in each of their matchups last season, and Luka Doncic only played in one of those four games. Expect LeBron James, Steph Curry, and Doncic to kick off their seasons with a bang.

NHL Picks

Chicago Blackhawks logo CHI @ Florida Panthers logo FLA Oct 07 | 5:00 PM ET
Spread
Florida Panthers logo FLA -1.5 (-135)
Best Odds
Pick made: one month ago
Gary Pearson image
Gary Pearson
Publishing Editor

The Florida Panthers should be healthy and have finally recovered from their celebratory binge after winning their second straight Stanley Cup. They'll be prepared for last season's NHL's worst road team. 

Total
Chicago Blackhawks logo Florida Panthers logo o5.5 (-130)
Best Odds
Pick made: one month ago
Gary Pearson image
Gary Pearson
Publishing Editor

The Florida Panthers will get back to business without suffering from a Stanley Cup hangover, primarily thanks to playing the lowly Chicago Blackhawks. The opener occurs in the Sunshine State, providing a more conducive platform for the Panthers to explode offensively. 

Pittsburgh Penguins logo PIT @ New York Rangers logo NYR Oct 07 | 8:00 PM ET
Total
Pittsburgh Penguins logo New York Rangers logo o5.5 (-125)
Best Odds
Pick made: one month ago
Gary Pearson image
Gary Pearson
Publishing Editor

The Pittsburgh Penguins had the sixth-worst defensive record on the road last season, and the New York Rangers conceded the ninth-most at Madison Square Garden. In addition, three of the previous four meetings had at least six goals. 

NCAAB Picks

The NCAAB is in the offseason. See the best odds on NCAAB futures and offseason news and analysis:

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Best sports picks & bets today

Seven days a week, 365 days a year, Sportsbook Review’s betting experts offer their best predictions and picks on the top games across all major leagues, with more than 20 years of experience in the sports betting industry to back us up.

Our picks widget (above) shows you our experts’ top predictions on each of the best games today and this week, with the betting odds and lines from legal and regulated sportsbooks. See our best picks on your favorite teams, players, and games. You’ll find the best odds and the best place to make your bets today!

Each day at SBR, you’ll find confident predictions on point spreads, totals (Over/Unders), and moneylines, in addition to team and player props, and parlays (plus SGPs!). We strive to find value and profit opportunities on the players you want to bet and the games you’ll be watching every day.

SBR’s team of experts hunts for value in the odds and betting lines by using advanced statistics, analytics, and the lines themselves to derive the best and most confident predictions. We break down team and player performance, and how recent results and outputs can factor into specific matchups.

Come back to this page for daily betting picks and advice from our experts at Sportsbook Review.

What free picks do we offer?

Here are some of the major sports and betting events we cover throughout the year at Sportsbook Review. You’ll find daily (or weekly) picks on every in-season sport, in addition to our coverage of the futures odds for championship and player award markets.

  • NFL picks: We offer picks on the biggest NFL games each and every week while keeping a close eye on the latest and best Super Bowl odds; follow us throughout the season for our best bets against the spread, total, and moneyline, along with touchdown scorer predictions, props, and parlay picks.
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  • College football picks: Stay on top of the latest in college football with our weekly coverage of the best games from Week 0 throughout the College Football Playoff and national championship. We break down the best ATS picks, totals, and player props on each game throughout bowl season.
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Free moneyline picks

A moneyline pick is simply wagering on who will win a game - no point spreads involved. Odds show favorites with a minus (‑) and underdogs with a plus (+).

Imagine the Knicks are favorites and the Nets are underdogs:

TeamMoneyline Odds
Knicks–250
Nets+400
  • $100 on Knicks (‑250) → Profit = $100 × (100 / 250) = $40 (total payout $140)
  • $100 on Nets (+400) → Profit = $100 × 4 = $400 (total payout $500)

Free Over/Under picks

Over/Under betting doesn’t care who wins the game, just how many points, runs, or goals are scored, or how long a fight lasts.

  • Book sets a line → i.e., Over/Under 54.5 for a football game
  • You choose:
    • Over 54.5
    • Under 54.5
  • Odds are usually around –110, meaning you bet $110 to win $100 (and your $110 stake returns $210 total)
  • If the final score is:
    • 56–22 (total 78) → Over wins
    • 24–20 (total 44) → Under wins
  • Pushes are avoided thanks to the half-point; i.e., 54.5 guarantees Over or Under wins
    • If the total is set at 54 and that’s the exact final score, all bets on either side will be refunded (voided) as a tie

Free spread picks

Our expert picks typically focus on picks against the spread as one of the most popular bets in any team sport. Run lines and puck lines are used in baseball and hockey, respectively, but refer to the same thing.

  • The favorite is shown with a minus (–) and must win by more than the spread to cover
  • The underdog has a plus (+) and must either win outright or lose by fewer points than the spread
  • Spreads often include a .5 (i.e., 3.5) to avoid a tie or “push.” If the final margin equals the exact spread, bets are refunded as a tie

Free prop picks

Prop picks allow bettors to target specific players, teams, or game events. Player prop odds vary based on probability - i.e., a prop might offer –110 odds (bet $110 to win $100) for a likely result or +250 (bet $100 to win $250) for less likely ones. Prop markets often present value opportunities, especially when sportsbooks pay less attention to niche events compared to main markets, and there are typically far more prop bets to choose from in any given game.

How we make our picks & predictions

Our No. 1 focus at Sportsbook Review is always on price shopping, and finding you the best betting line and odds for each pick. Why should you pay more (bet shorter odds) when you can fetch a greater profit at a different sportsbook all while needing the exact same outcome on your bet?

This is the most important part of the process for any game picks, player props, and futures bets. To be a winning bettor over the long term, you simply can’t be leaving money on the table by betting shorter odds when better numbers are out there.

However, this step typically follows our experts' analysis of matchups using advanced statistics, as well as player and team performance, to determine their best bets in any given betting market. Certain matchups favor certain players or positions, and we always look to who’s best equipped for success in those matchups when starting our game picks and player props.

We caution against putting too much emphasis on injuries, weather, or any narrative or news-based factor. The sportsbooks are almost always ahead of this when it comes to setting and adjusting their lines. Bettors don’t have an edge just because Patrick Mahomes won’t be playing against the Broncos on Sunday. That’s already been baked into the lines.

It’s important to balance betting on favorites, underdogs, and long shots. Favorites come with shorter odds for a reason, but they don’t always win. It’s equally important to know that longer odds represent a lower probability of a winning bet. Diversify your betting portfolio, manage your bankroll, and track your results.

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Sportsbook Review has been around for more than 20 years, and is a trusted source of betting picks as well as honest reviews of our best sports betting sites.

We carefully match our betting experts to the sports and topics they’re most passionate about to recommend picks they’re betting themselves. Our 1-to-5-star confidence rating is based on the matchup, their research, and the implied probability of the odds. It’s rare to see a 5-star pick on home run and touchdown predictions, as well as futures bets, due to the inherent nature of those betting markets and the lower implied probability of the longer odds.

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