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After another week of drama in the European Cup,  some top-class football around the biggest leagues will keep fans connected to the beautiful game. Here are our best bets from the Serie A, La Liga, Bundesliga, and other big leagues based on the best soccer odds.

There will be intense action in the German Bundesliga and in the French Ligue 1, as Bayern Munich take on Union Berlin and Paris Saint-Germain face arch-rivals Marseille.

Milan vs. Atalanta is the game of the weekend in Serie A, while Spain hosts the big Madrid derby between Real and Atletico.

Here are our best soccer bets from Serie A, La Liga, Bundesliga, and other top leagues (odds via Bet MGM and FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Check out our soccer picks.

Soccer best matches and odds this week

(odds via FanDuel)

  • La Liga: Real Madrid (-135) vs. Atletico Madrid (+360)
  • La Liga: Almeria (+600) vs. Barcelona (-240)
  • Serie A: AC Milan (+115) vs. Atalanta (+230)
  • Bundesliga: RB Leipzig (-165) vs. Frankfurt (+370)
  • Bundesliga: Bayern Munich(-340) vs. Union Berlin (+700)
  • Ligue 1: Marseille (+175) vs. Paris Saint-Germain (+140)

Soccer best bets this week

  • Total: Werder vs. Bochum Over 3.5 (+182 via FanDuel) ⭐⭐⭐⭐
  • Spread: Barcelona -1 vs. Almeria (+110 vs BetMGM) ⭐⭐⭐⭐
  • Moneyline: Sevilla vs. Osasuna (-111 via BetMGM) ⭐⭐⭐
  • Parlay: Hoffenheim vs. Dortmund: Marco Reus anytime goalscorer + Over 2.5 goals + Over 7.5 corners (+240 via BetMGM) ⭐⭐⭐

Top soccer picks

Total: Werder vs. Bochum Over 3.5 (+182 via FanDuel) ⭐⭐⭐⭐

Werder have a special appetite for scoring, and bettors are surely aware of this by now. When it comes to facing Bochum, they love to go over the top.

Werder have scored at least twice in 14 of their last 17 matches against Bochum in all competitions. They have also had Over 2.5 goals scored in their last six home encounters against Bochum, winning seven of their last eight direct clashes at home.

Add to that the fact that Bochum conceded at least twice in their last five Bundesliga outings and you can believe this is going to be an eventful match, to say the least.

Spread: Barcelona -1 vs. Almeria (+110 vs BetMGM) ⭐⭐⭐⭐

Barcelona and Almeria are separated by 16 places and 37 points in the La Liga table after 22 matches. Frustrated after being knocked out of the Europa League by Manchester United, Barcelona will certainly look to regain confidence with a solid win vs. Almeria.

History has always been on their side over the last 10 years, with big wins recorded against Almeria in 2013 (3-1), 2014 (4-1), and 2015 (4-0). Almeria lost all their previous three La Liga games, with the negative run also including a 6-2 thrashing from Girona last week.

Moneyline: Sevilla ML vs. Osasuna (-111 via BetMGM) ⭐⭐⭐

Sevilla sit in 12th place after 22 matches, well back from what many expected from this team.

Meanwhile, Osasuna are 10th, with a five-point gap separating the two sides. Sevilla will try to please the fans they’ve disappointed on so many occasions during the current campaign, so they will go forward looking for goals, also trying to profit from Osasuna’s inconsistent form.

Parlay: Hoffenheim vs. Dortmund: Reus anytime goalscorer + Over 2.5 goals + Over 7.5 corners (+325 via BetMGM) ⭐⭐⭐

In-form Dortmund take on a team that has lost its last five official outings.

Hoffe are far from the side they were a few seasons ago. They conceded 16 goals in the five matches they’ve lost since Jan. 24, and they might be involved in another high-scoring match at the weekend.

Dortmund have won all the games they've played in 2023, haunting Bayern at the top of the Bundesliga table. Given the circumstances, they should not let a comfortable win slip.

Marco Reus, who netted twice in Dortmund’s four previous matches, is a great candidate to add to his season tally given the influence and bite he has in BVB’s game.

European Soccer odds and best bets from 2/23/2022 at 1:41 p.m. ET.

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