Best March Madness Sweet 16 Parlay: Best Moneyline Picks Today With +1300 Odds
The favorites weren't perfect against the spread to open the Sweet 16 but still won every game outright. Our best March Madness Sweet 16 parlay bets are expecting at least one upset to cash tonight with our four-leg moneyline parlay at +1300 odds.
👉 Can't get enough March Madness action? Check out the latest March Madness Sweet 16 odds & full schedule and the rest of our March Madness predictions.
💰 Our best March Madness parlay bets today for the NCAA Tournament
Here are the best odds for our March Madness Sweet 16 parlay using our NEW parlay calculator to instantly determine the best price across our best sports betting sites.
🔥 Michigan State (-170) vs. Ole Miss
🔥 Kentucky (+155) vs. Tennessee
🔥 Auburn (-385) vs. Michigan
🔥 Houston (-365) vs. Purdue
🚀 Best parlay odds: +1300 via FanDuel ($10 to win $130)
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🏀 Michigan State vs. Ole Miss prediction, 7:09 p.m. ET (CBS), South Region
🎯 Score prediction: Michigan State 76, Ole Miss 67
💰 Best Michigan State moneyline odds: -169 via Caesars
Here's why Phil Wood is picking Michigan State to win outright:
"Michigan State will put together a better offensive performance than we saw in the second round, as it plays looser after surviving the first weekend. While Ole Miss can score a lot, the Spartans' defense will shut the offense down, keeping this game lower scoring than many expect."
👉 For more analysis & latest odds, check out our Michigan State vs. Ole Miss prediction.
📊 Michigan State vs. Ole Miss odds
🏀 Tennessee vs. Kentucky prediction, 7:39 p.m. ET (TBS/truTV), Midwest Region
🎯 Score prediction: Kentucky 74, Tennessee 70
💰 Best Kentucky moneyline odds: +176 via FanDuel
Here's why Brenden Schaeffer is picking Kentucky to win outright:
"It’s hard to beat a good team three times in one season, but Kentucky has shown it knows how to get the job done. Kentucky averages 85.0 PPG and has cracked the Tennessee defense twice this year. In essence, I’m banking on Kentucky to get into its tempo, again scoring in the 70s, where the Wildcats would have an advantage."
👉 For more analysis & latest odds, check out our Tennessee vs. Kentucky prediction.
📊 Tennessee vs. Kentucky odds
🏀 Auburn vs. Michigan prediction, 9:39 p.m. ET (CBS), South Region
🎯 Score prediction: Auburn 79, Michigan 73
💰 Best Auburn moneyline odds: -385 via FanDuel
Here's why Phil Wood is picking Auburn to win outright:
"Bettors may anticipate both schools getting into the 80s, as each squad averages at least 78.3 points per game. But we’ve seen the Tigers and Wolverines play low-scoring affairs in recent weeks. The Wolverines will lose but cover, and the total will just barely go Under 153.5 points."
👉 For more analysis & latest odds, check out our Auburn vs. Michigan prediction.
📊 Auburn vs. Michigan odds
🏀 Houston vs. Purdue prediction, 10:09 p.m. ET (TBS/truTV), Midwest Region
🎯 Score prediction: Houston 75, Purdue 64
💰 Best Houston moneyline odds: -365 via FanDuel
Here's why Brenden Schaeffer is picking Houston to win outright:
"Purdue's offensive efficiency suffered when tasked against high-caliber defensive teams like Texas A&M, Auburn, Michigan State, Marquette, and Indiana this season, as they never eclipsed 70 points. Houston is the best of that bunch defensively, ranking No. 1 in adjusted defensive efficiency this season."
👉 For more analysis & latest odds, check out our Houston vs. Purdue prediction.
📊 Houston vs. Purdue odds
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🗓️ Sweet 16 schedule & TV info today
- No. 2 Michigan State vs. No. 6 Ole Miss, 7:09 p.m. ET (CBS), South Region
- No. 2 Tennessee vs. No. 3 Kentucky, 7:39 p.m. ET (TBS/truTV), Midwest Region
- No. 1 Auburn vs. No. 5 Michigan, 9:39 p.m. ET (CBS), South Region
- No. 1 Houston vs. No. 4 Purdue, 10:09 p.m. ET (TBS/truTV), Midwest Region
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