March Madness AI Predictions Today: Exact Score Picks for Thursday's NCAA Tournament Games

It's hard enough for humans to predict March Madness, but can AI crack the code? We asked ChatGPT for its March Madness AI bracket predictions, and now we're putting it to the test with exact score predictions based on live NCAA Tournament data.

Here's a look at what ChatGPT has predicted for all 16 games today, with an exact score prediction and AI-generated insights from the popular chatbot by OpenAI.

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🏀 Louisville vs. Creighton AI pick & score prediction (12:15 p.m. ET, CBS)

🎯 AI score prediction: Louisville 75, Creighton 72

• The last time these two teams met in the NCAA Tournament, Louisville beat Creighton in overtime 69-66. That game was played on March 11, 1999.
• KenPom analytics give Louisville a 60% chance of winning this matchup.
• Under the leadership of Coach Pat Kelsey, Louisville has experienced a remarkable turnaround, finishing the season with a 27-7 record.

👉 For more expert (human) analysis, check out our Louisville vs. Creighton prediction.

📊 Louisville vs. Creighton odds

🏀 Purdue vs. High Point AI pick & score prediction (12:40 p.m. ET, truTV)

🎯 AI score prediction: Purdue 78, High Point 68

• The Boilermakers’ frontcourt dominance, led by their physical interior play, gives them a significant rebounding and scoring edge, making it tough for High Point to keep up.
• While High Point is on a 14-game winning streak and 13 seeds have a history of upsetting 4 seeds, Purdue’s superior strength of schedule and defensive efficiency make the upset unlikely.
• Purdue’s recent struggles (losing six of its last nine) create some value on High Point against the spread, but Purdue’s overall talent and tournament experience should prevail.

👉 For more expert (human) analysis, check out our Purdue vs. High Point prediction.

📊 Purdue vs. High Point odds

🏀 Wisconsin vs. Montana AI pick & score prediction (1:30 p.m. ET, TNT)

🎯 AI score prediction: Wisconsin 71, Montana 62

• Wisconsin has been a consistent presence in the NCAA Tournament. The Badgers reached the Sweet 16 in 2021 and have made the tournament in almost every season for the past two decades.
• The Grizzlies prefer to control the pace, slowing the game down and taking high-percentage shots. This could be an advantage in keeping high-powered offenses at bay.
• Both teams excel defensively, but Wisconsin’s size, experience, and ability to defend without fouling give it a crucial edge. Montana will struggle to break down Wisconsin’s disciplined defense for consistent offense.

👉 For more expert (human) analysis, check out our Wisconsin vs. Montana prediction.

📊 Wisconsin vs. Montana odds

🏀 Houston vs. SIU Edwardsville AI pick & score prediction (2 p.m. ET, TBS)

🎯 AI score prediction: Houston 78, SIU Edwardsville 51

• The Cougars allow only 58.5 points per game, ranking second nationally in scoring defense. Their aggressive perimeter defense and shot-blocking ability should smother SIU Edwardsville's offense, forcing turnovers and contested shots.
• Regardless of the outcome, this game marks a historic moment for SIU Edwardsville. Its OVC Championship run was impressive, and guard Taylor will look to make an impact, but it's facing an elite Houston squad that has thrived in March for years.
• While known for their defense, the Cougars also feature an efficient and balanced offensive attack. Led by L.J. Cryer, Houston shoots 36% from three-point range and excels at moving the ball to find open looks. Houston's shooters should have a big day against an SIU Edwardsville team that struggles to defend the perimeter.

👉 For more expert (human) analysis, check out our Houston vs. SIU Edwardsville prediction.

📊 Houston vs. SIU Edwardsville odds

🏀 Auburn vs. Alabama State AI pick & score prediction (2:50 p.m. ET, CBS)

🎯 AI score prediction: Auburn 90, Alabama State 65

• While Alabama State's return to the tournament is a significant achievement, Auburn's overall strength and tournament pedigree make them the clear favorites.
• Historically, No. 1 seeds have dominated No. 16 seeds: only in 2018, when UMBC defeated Virginia, and in 2023, when Fairleigh Dickinson beat Purdue, has the underdog won.
• The Hornets secured their tournament berth by winning the SWAC tournament, ending a 14-year absence from the NCAA Tournament.

👉 For more expert (human) analysis, check out our Auburn vs. Alabama State prediction.

📊 Auburn vs. Alabama State odds

🏀 Clemson vs. McNeese AI pick & score prediction (3:15 p.m. ET, truTV)

🎯 AI score prediction: Clemson 74, McNeese 67

• The Tigers’ inside-out attack, led by Chase Hunter and a strong frontcourt, allows them to control the tempo and exploit mismatches.
• The Cowboys rank among the best mid-majors in scoring efficiency and have the athleticism to challenge Clemson. No. 12 seeds have historically won about 35% of matchups against No. 5 seeds.
• The Tigers allow just 66.8 PPG, ranking among the ACC’s best defenses. If they can limit McNeese’s perimeter shooting, they should pull away late.

👉 For more expert (human) analysis, check out our Clemson vs. McNeese prediction.

📊 Clemson vs. McNeese odds

🏀 BYU vs. VCU AI pick & score prediction (4:05 p.m. ET, TNT)

🎯 AI score prediction: VCU 72, BYU 64 

• VCU enters the tournament having dominated the Atlantic 10 Conference, known for its defensive intensity and fast-paced offense. Its success comes from its ability to force turnovers, which helps generate easy transition baskets. It also has a well-balanced offense that can score both inside and outside.
• The Rams are known for being a high-pressure team that thrives in the chaos of the tournament setting.
• Teams that rely on perimeter shooting, like BYU, can thrive if they catch fire. However, against a team like VCU that's designed to stifle shooters and push the tempo, BYU will need to be efficient from the outside to avoid getting overwhelmed.

👉 For more expert (human) analysis, check out our BYU vs. VCU prediction.

📊 BYU vs. VCU odds

🏀 Gonzaga vs. Georgia AI pick & score prediction (4:35 p.m. ET, TBS)

🎯 AI score prediction: Gonzaga 81, Georgia 74

• The Bulldogs rank top-five nationally in scoring (86.6 PPG) and assists (19.7 APG). Their ability to spread the floor and find high-percentage shots will be a challenge for Georgia’s inconsistent defense.
• The Bulldogs shoot just 33.1% from three, which could hurt them if they fall behind early. However, if Asa Newell and Silas Demary Jr. can get hot from deep, they have the firepower to keep it close.
• Mark Few’s squad has been a March Madness staple, while Georgia is making its first NCAA Tournament appearance since 2015. Experience in pressure moments could be the deciding factor down the stretch.

👉 For more expert (human) analysis, check out our Gonzaga vs. Georgia prediction.

📊 Gonzaga vs. Georgia odds

🏀 Tennessee vs. Wofford AI pick & score prediction (6:50 p.m. ET, TNT)

🎯 AI score prediction: Tennessee 81, Wofford 62

• The Vols rank among the top defensive teams in the nation, creating significant matchup problems for Wofford, which lacks the scoring firepower to keep pace.
• Tennessee’s roster features several upperclassmen with NCAA Tournament experience, giving them a composure advantage in high-pressure moments.

👉 For more expert (human) analysis, check out our Tennessee vs. Wofford prediction.

📊 Tennessee vs. Wofford odds

🏀 Kansas vs. Arkansas AI pick & score prediction (7:10 p.m. ET, CBS)

🎯 AI score prediction: Kansas 75, Arkansas 71

• Kansas' dominant frontcourt, led by Hunter Dickinson, presents a significant challenge for Arkansas, especially with the Razorbacks' struggles against athletic bigs this season.
• The absence of Arkansas' leading scorer, Thiero, due to a knee injury, hampers their offensive capabilities and depth.
• Kansas' experience in the NCAA Tournament, coupled with their strong defensive metrics, positions them favorably against an Arkansas team that has faced inconsistencies.

👉 For more expert (human) analysis, check out our Kansas vs. Arkansas prediction.

📊 Kansas vs. Arkansas odds

🏀 Texas A&M vs. Yale AI pick & score prediction (7:25 p.m. ET, TBS)

🎯 AI score prediction: Texas A&M 72, Yale 62

• Texas A&M generally has a strong defense and a physical style of play. Historically, it's been able to dominate on the boards and slow down opponents.
• The final score assumes Texas A&M dominates in the paint and takes advantage of its defensive strength, while Yale may struggle to score consistently against the Aggies’ defense.
• Yale tends to have a more balanced approach but often struggles when playing teams with high-level athleticism and depth, which is typical of schools from major conferences like the SEC, where Texas A&M resides.

👉 For more expert (human) analysis, check out our Texas A&M vs. Yale prediction.

📊 Texas A&M vs. Yale odds

🏀 Missouri vs. Drake AI pick & score prediction (7:35 p.m. ET, truTV)

🎯 AI score prediction: Missouri 75, Drake 68

• Missouri's high-octane offense, averaging 84.5 points per game, contrasts sharply with Drake's methodical pace, which ranks as the slowest in the nation. This tempo disparity will be pivotal in determining the game's rhythm.
• Drake's defensive prowess, allowing just 58.4 points per game - the best in the country - will be tested against Missouri's versatile scoring options, including Mark Mitchell and Caleb Grill.
• The Bulldogs' experience, with four starters transitioning from Division II under coach Ben McCollum, has translated into a remarkable 30-3 record, showcasing their resilience and cohesion.

👉 For more expert (human) analysis, check out our Missouri vs. Drake prediction.

📊 Missouri vs. Drake odds

🏀 UCLA vs. Utah State AI pick & score prediction (9:25 p.m. ET, TNT)

🎯 AI score prediction: UCLA 74, Utah State 68

• The Bruins boast a top-20 defense, allowing just 62.3 points per game, which could stifle Utah State's offense.
• The Aggies rank in the top 10 nationally for 3-point shooting percentage, making them a potential threat from beyond the arc.
• In the past five tournaments, No. 10 seeds have won 40% of their matchups against No. 7 seeds, indicating a higher upset potential in this seeding.

👉 For more expert (human) analysis, check out our UCLA vs. Utah State prediction.

📊 UCLA vs. Utah State odds

🏀 St. John's vs. Omaha AI pick & score prediction (9:45 p.m. ET, CBS)

🎯 AI score prediction: St. John's 83, Omaha 66

• St. John's boasts an elite defense, ranking first nationally in adjusted defensive efficiency, which could stifle Omaha's offense that has thrived against less formidable defenses.
• Omaha's lack of experience against top-tier teams, with a 32-point loss to Iowa State earlier in the season, suggests potential struggles against a powerhouse like St. John's.
• The Red Storm's offensive rebounding strength, led by Zuby Ejiofor's 8.0 rebounds per game, may exploit Omaha's defensive vulnerabilities, leading to second-chance points.

👉 For more expert (human) analysis, check out our St. John's vs. Omaha prediction.

📊 St. John's vs. Omaha odds

🏀 Michigan vs. UC San Diego AI pick & score prediction (10 p.m. ET, TBS)

🎯 AI score prediction: Michigan 73, UC San Diego 72

• UC San Diego excels in defensive pressure, ranking second nationally in forcing turnovers, which could disrupt Michigan's offensive flow.
• Michigan is ranked 25th in KenPom, while UC San Diego sits at 36th, indicating a relatively narrow gap in overall efficiency.
• UC San Diego's momentum, defensive prowess, and the historical propensity for upsets in this matchup suggest it will be a closely contested game.

👉 For more expert (human) analysis, check out our Michigan vs. UC San Diego prediction.

📊 Michigan vs. UC San Diego odds

🏀 Texas Tech vs. UNC Wilmington AI pick & score prediction (10:10 p.m. ET, truTV)

🎯 AI score prediction: Texas Tech 81, UNC Wilmington 67

• Texas Tech's potent offense, averaging 80.9 points per game, is expected to exploit UNC Wilmington's defense, which has struggled against high-scoring teams.
• The Red Raiders' strong three-point shooting (37.9%) poses a significant challenge for the Seahawks, whose perimeter defense ranks 298th nationally.
• Texas Tech's experience and depth, coupled with their motivation following last year's early tournament exit, position them favorably against a less battle-tested UNC Wilmington squad.

👉 For more expert (human) analysis, check out our Texas Tech vs. UNC Wilmington prediction.

📊 Texas Tech vs. UNC Wilmington odds

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