Akron vs. Creighton Prediction & March Madness Odds: Will Bluejays Win Big?

Check out our Akron vs. Creighton prediction for Thursday's March Madness matchup based on the best college basketball odds.

The Creighton Bluejays and Akron Zips clash in a battle of the Midwest in the first round of the NCAA Tournament, and we have you covered with our top Akron vs. Creighton prediction based on the best March Madness odds.

The No. 14 Akron (24-10, 13-5 MAC) got off to a blistering start in conference play but lost four of six games to end the regular season before rebounding with three straight wins in the MAC Tournament. The Zips won their last two MAC Tournament games by four combined points.

The No. 13 Creighton Bluejays (23-9, 14-6 Big East) won seven of eight games to end the regular season, a span which included wins over the top two teams in the Big East, UConn and Marquette, by 33 combined points. Despite losing in the quarterfinals in the conference tournament to Providence, they still earned a No. 3 seed, matching the school’s best seed in an NCAA Tournament appearance. 

Despite losing in the conference tournament quarterfinals to Providence, the Bluejays still earned a No. 3 seed, matching the school’s best seed for an NCAA Tournament appearance. 

As part of our March Madness predictions, here is our best Akron vs. Creighton prediction and college basketball picks (odds via our best March Madness betting sites; pick confidence based on a 1-to-5-star scale).

Akron vs. Creighton odds

Akron (14) vs. Creighton (3) prediction: Midwest Region

Creighton -15.5 alt spread ⭐⭐⭐

Best odds: +140 via DraftKings

Creighton is one of the smartest teams for bettors to get involved with from an alternate spread perspective based on the volatility of its 3-point shooting.

In blowout wins in the last month against two of the best defensive teams in the country, UConn and Marquette, the Bluejays combined to shoot 27-for-60 (45%) from beyond the arc and covered the spreads in those games by a margin of nearly 14 points despite allowing each team to score 1.10 points or more per possession.

We do not expect an Akron team that shot 3-pointers at the seventh-highest clip in MAC play to have the firepower to keep up with a Creighton squad that is the only team in the country to have three players averaging at least 17 points per game.

The Zips are just 3-8 ATS in their last 11 games, making them ripe to fade on an alternate spread.

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Akron vs. Creighton best odds

DraftKings (+140)

DraftKings FanDuel BetMGM Caesars bet365
-15.5 -15.5 -12.5 -12.5 -14.5
+140 +134 -115 -110 +120

BetMGM and Caesars weren't offering alternate spreads at the time of writing, and bet365’s alternate spread market tops out at -14.5.

Thus, we are taking advantage of the best payout at DraftKings at +140 odds, though more adventurous bettors can head to FanDuel and back Creighton as high as -21.5 for +285 odds.

The difference between DraftKings’ +140 odds and FanDuel’s +134 odds on a $10 wager means being paid out $14 compared to $13.40.

We are asking Creighton to cover a spread three points higher than the original number, which is something it has done in six of its last seven outright covers.

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Akron vs. Creighton spread & Over/Under analysis

All of our best sports betting sites are in unison with a standard spread of Creighton -12.5.

DraftKings has seen the biggest line movement off of its original number of -13.5 (making a stop at -13 along the way), while the only other changes at other best sports betting apps have been in adjusting the juice on either side of the spread.

The early wagers are split 72/28 in favor of Creighton, so it is likely the spread will move in its favor at most of our best sportsbooks if the splits continue to be this one-sided before tip-off.

As was the case with the point spread, the total for this contest seems an equally sharp number, as all of our best live betting sites are in unison with an O/U of 141.5.

Bettors drove the line up at BetMGM from an opening number of 139.5, while all other competing sportsbooks are up from opening totals of 140 and 140.5. The betting splits support this movement, as early wagers are nearly 3/1 (73/27) on the Over.

Akron vs. Creighton game info

  • When: Thursday, March 21
  • Tip-off: 1:30 p.m. ET
  • Where: PPG Paints Arena, Pittsburgh, Pa.
  • How to watch: TNT

Akron-Creighton prediction made Monday at 2:09 p.m. ET.

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