Mariners vs. Blue Jays Player Props: MLB Picks & Best Bets for ALCS Game 6

Last Updated: October 19, 2025 8:01 AM EDT • 3 minute read X Social Google News Link

Seattle is looking to advance to the Fall Classic for the first time in franchise history, and I’m breaking it down with my best Mariners vs. Blue Jays player props for ALCS Game 6.
The Blue Jays are the slight -125 moneyline betting favorite, but are a relative long shot in the World Series odds. First pitch is set for 8:03 p.m. ET from Rogers Centre in Toronto (FS1). My MLB picks for Game 6 expect Vladimir Guerrero Jr. and Julio Rodriguez to make noise at the plate and Trey Yesavage to have his best stuff.
⚾ Mariners vs. Blue Jays player props: ALCS Game 6
MLB player prop bets for Game 6; odds subject to change.
- Trey Yesavage Over 4.5 strikeouts (-145 via BetMGM) ⭐⭐⭐
- Julio Rodriguez Over 0.5 runs scored (+104 via DraftKings) ⭐⭐
- Vladimir Guerrero Jr. Over 0.5 walks (+145 via Caesars) ⭐⭐⭐⭐
- Julio Rodriguez to hit a home run (+455 via DraftKings) ⭐
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💰 Best player prop bets for Mariners vs. Blue Jays Game 6
Our MLB player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬆️ Trey Yesavage Over 4.5 strikeouts (-145) ⭐⭐⭐
Yesavage fanned four in four innings in Game 2. The Mariners have struck out 26.3% of the time in the ALCS thus far and are chasing over 70% of the time through five games.
Yesavage settled in nicely after giving up three runs in the first. He’s already proven the postseason spotlight isn’t too bright, and I think his fastball/splitter combination should be able to keep Seattle’s lineup off balance more than in Game 2.
A $10 bet on Yesavage’s Over yields a profit of $6.90 at BetMGM. The -145 odds have an implied probability of 59.18%.
⬆️ Julio Rodriguez Over 0.5 runs scored (+104) ⭐⭐
Rodriguez crossed the plate in Games 1 and 2 in Toronto. He hit a three-run homer off Yesavage in Game 2 and scored 64 of his 106 regular-season runs away from T-Mobile Park.
A $10 wager on Rodriguez to hit the Over on this player prop would provide a profit of $10.40 at DraftKings, which provides the best value of the best sports betting sites. The +104 odds carry an implied probability of 49.02%.
⬆️ Vladimir Guerrero Jr. Over 0.5 walks (+145) ⭐⭐⭐⭐
Guerrero was intentionally walked twice in Game 5. He's seen Logan Gilbert well throughout his career, and I expect Mariners manager Dan Wilson to avoid giving Guerrero a chance to do damage whenever the opportunity presents itself.
A $10 winning wager on Guerrero to record at least one walk would provide a profit of $14.50. The implied probability of the +145 odds is 40.82%.
🚀 Best home run prediction for Mariners vs. Blue Jays Game 6
Track the latest MLB scores for line movement and matchup info.
💣 Julio Rodriguez to hit a home run (+455) ⭐
Rodriguez was a completely different hitter on the road in 2025, posting a .912 OPS, compared to a .676 mark at home.
Rodriguez hit .253 with a .518 slugging percentage against offspeed pitches this season. He also hit 17 home runs with a .279 batting average against fastballs. His ability to see a variety of different pitches should continue to serve him well against Yesavage’s pitch mix.
A $10 winning bet on Rodriguez to hit a home run would provide a profit of $45.50 at DraftKings. The +455 odds carry an implied probability of 18.02%.
📊 Mariners vs. Blue Jays odds: Game 6
Latest MLB odds updated live in real time.
📺️ How to watch Mariners vs. Blue Jays: Game 6
- Date: Sunday, Oct. 19
- First pitch: 8:03 p.m. ET
- Where: Rogers Centre (Toronto)
- TV: FS1
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