College Football Week 0 Predictions 2023: Picks, Odds, and Best Bets

Rounding up our best college football picks and predictions for Week 0. ML, ATS, O/U, and prop plays for a big payday.
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After a long spring and summer, the season is here, and this page rounds up all of our best college football picks and predictions for Week 0.

College football is back in style with Saturday's seven-game slate marking the unofficial Week 0.

We'll have 11 more games Thursday, Aug. 31 and six on Friday before Week 1's first full Saturday on Sept. 2.

With No. 13 Notre Dame and No. 6 USC headlining Saturday's action, our college football betting experts are offering up all of their favorite picks to help you get your betting season started on the right foot leading all the way to the 2024 CFP National Championship.

Check out all of our best college football picks and predictions for Week 0 based on the best NCAAF odds (odds via our best college football betting sites).

College Football picks: Week 0

UMass vs. New Mexico State Over 44.5 pick (-115 via FanDuel) ⭐⭐⭐

Check out our BetMGMbet365, and Caesars promo codes for UMass-New Mexico State

Pick made by Shane Jackson

Ohio vs. San Diego State (ML) pick (-125 via Caesars) ⭐⭐⭐⭐

Pick made by Shane Jackson

Hawaii (+17.5) vs. Vanderbilt pick (-108 via DraftKings) ⭐⭐⭐

Pick made by Mike Spector

San Jose State vs. USC Over 66 pick (-112 via DraftKings) ⭐⭐⭐

Pick made by Mike Spector

FIU vs. Louisiana Tech (-11) pick (-113 via BetRivers) ⭐⭐⭐

Pick made by Mike Spector

College football expert picks for Week 0

College football odds pages

How to bet on college football

In the dynamic world of college football betting, success requires a blend of strategy and analysis.

First, research team statistics, recent performance, and player injuries. Identify key matchups and track trends like home-field advantage. Look beyond the headlines to assess team morale and coaching strategies.

Next, understand the point spread – it's not just about predicting the winner, but also the margin of victory. Moneyline bets focus solely on the winner, while Over/Under bets predict total points scored. Parlays combine multiple bets for bigger payouts, but are riskier. Remember, responsible bankroll management is essential – never wager more than you can afford to lose.

Lastly, stay updated with real-time odds and news as they can affect betting decisions. College football betting demands astute insight, adaptable strategies, and a disciplined approach.

Here are our best college football betting sites:

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