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A general view in the second half during the 2021 NCAA Final Four semifinal as well look at the Final Four odds 2023.
A general view in the second half during the 2021 NCAA Final Four semifinal between the Houston Cougars and the Baylor Bears at Lucas Oil Stadium on April 03, 2021 in Indianapolis, Indiana. Photo by Andy Lyons /Getty Images via AFP.

We're down to 16 teams remaining in the March Madness field. Below, we look at who's most likely to win each NCAA Tournament region in the Final Four odds.

No. 1 teams Purdue and Kansas have been eliminated from the 2023 NCAA Tournament field. They're joined by top seeds Arizona, Marquette, and Baylor on the sidelines entering Sweet 16 and Elite Eight play this week. The Final Four odds can help you with your March Madness picks for this week's games.

Here's our look at the best 2023 Final Four odds (odds via DraftKings SportsbookFanDuel Sportsbook, BetMGM, Caesars, and PointsBet).

Final Four odds 2023

Odds to win West region


West region odds

Defending champion Kansas was knocked out of March Madness on Saturday, proving the books right in what seemed like inflated odds for the Jayhawks to win the West region. Our top sports betting sites UConn a slight edge over No. 2 UCLA in the remaining Final Four odds. UConn and Gonzaga are both featured prominently in our March Madness picks and may represent some value in your March Madness upset predictions.

Odds to win East region

Michigan State+300+270+300+300+300
Kansas State+350+320+340+350+325
Florida Atlantic+450+470+440+420+450

East region odds

Purdue, the Big Ten champion this season, was eliminated by No. 16 Fairleigh Dickinson on Friday night. That briefly left the East region as the most wide-open of the four quadrants but Tennessee has taken a strong hold as the new favorite.

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Odds to win South region

San Diego State+600+650+550+600+550

South region odds

There's a fair bit of separation between No. 1 Alabama and Creighton in the odds to win the South Region with Alabama being one of two regional favorites laying minus odds entering the Sweet 16.

Odds to win Midwest region


Midwest region odds

Houston opened March Madness as the heaviest favorite of the four No. 1 seeds entering Round 1. The Cougars are now the biggest favorites in the region winner markets entering the Sweet 16. The Cougars' biggest test by these odds will come from No. 2 Texas in a potential Elite Eight encounter.

Texas Longhorns celebrate after defeating the Kansas Jayhawks as we look at the Final Four odds.
Texas Longhorns celebrate after defeating the Kansas Jayhawks in the Big 12 Tournament Championship game at T-Mobile Center on March 11, 2023 in Kansas City, Missouri. Photo by Jamie Squire/Getty Images via AFP.

Recent March Madness winners

Odds from

YearTeamClosing Odds
2016-2017North Carolina+2400
2015-2016Villanova +2600
2013-2014Connecticut +7000

March Madness FAQs

Who won March Madness last year?

The Kansas Jayhawks defeated the North Carolina Tar Heels 72-69 to win the 2022 NCAA Tournament.

When does March Madness 2023 start?

Selection Sunday is set to occur on Sunday, March 12, 2023, four days before the tournament kicks off on March 16. The first round will be played on March 16 and 17.

When will March Madness be decided?

The 2023 Final Four will be held on Saturday, April 1, 2023. The National Championship Game takes place the following Monday on April 3, 2023.

Where will March Madness be played?

The 2023 Final Four and National Championship Game will be held in Houston, TX, at NRG Stadium.

Here are our best March Madness betting sites:

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* Bonuses not applicable in Ontario.

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