Athletics vs. Tigers Prediction, Picks & Odds for Today's MLB Game

American League Cy Young front-runner Tarik Skubal takes the mound looking to mow down the Athletics.

Sean Tomlinson

Last Updated: June 24, 2025 11:18 AM EDT • 3 minute read

Athletics vs Tigers prediction — Pictured Detroit Tigers pitcher Tarik Skubal walks off the field. Photo by Junfu Han / USA TODAY NETWORK via Imagn.

Scoring is nearly impossible against Detroit Tigers ace Tarik Skubal, and the Athletics face a daunting task while beginning a three-game series at Comerica Park in Detroit, with first pitch tonight at 6:40 p.m. ET. However, we're looking toward the opposing pitcher for the primary pick in our Athletics vs Tigers prediction.

The Tigers enter as the -275 favorite in the best MLB odds.

Athletics vs Tigers prediction

My Athletics vs Tigers best bet: Luis Severino Under 4.5 strikeouts (-120 via BetMGM)

Our best MLB betting sites are already all over Skubal's totals since he's such a dominant pitcher and popular among bettors, zapping the value.

His strikeout total is set to 8.5, which is a high bar for even him to clear, and one he's gone below in five of his last six starts. He's projected for 7.5 strikeouts, and the Under on 8.5 is juiced all the way to -155 in some spots.

So, instead, we turn to the opposing hurler. Luis Severino's punchout ability barely has a pulse anymore, making his strikeout Under far more appealing for one of our MLB picks today. He's also primed to pick on, as Andrew Brennan outlines in his Home Run Predictions.

His K/9 has kept gradually falling since a height of 12.8 back in 2019, with injuries surely playing a role. It now sits at a mere 6.2, and he's recorded a measly one strikeout in two of his last four starts.

Be sure to make this play at BetMGM, as several of our other best sports betting sites are sitting notably shorter around -130, with FanDuel at -132.

Athletics vs Tigers same-game parlay (SGP)

Luis Severino Under 4.5 strikeouts (-120)
Tarik Skubal Under 1.5 earned runs allowed (-161)
Tigers -2.5 (+114)

+360 via BetMGM

All eyes are on Skubal both this night and any time he's on the mound, which happens when you're steamrolling everyone and everything en route to being the runaway Cy Young odds favorite in the AL.

If you're itching to get some action on him, working Skubal into an SGP to boost the odds is one route to take. Skubal's ERA of 2.06 sits fourth leaguewide, and he's tossed a shutout while throwing at least six innings six times this season, including a nine-inning gem against the Cleveland Guardians in late May.

Athletics vs Tigers odds

Athletics vs Tigers live odds

View matchup | View all MLB odds

Athletics vs Tigers opening odds

Moneyline: Athletics (+230) | Tigers (-275)
Run line: Athletics +1.5 (+105) | Tigers -1.5 (-125)
Over/Under: Over 6.5 (-140) | Under 6.5 (+110)

Athletics vs Tigers trend

The Tigers are 26-12 at Comerica Park, putting them behind only the New York Mets MLB-wide in home losses.

How to watch Athletics vs Tigers and game info

Location	Comerica Park, Detroit
Date	June 24, 2025
First pitch	6:40 p.m. ET
TV	FanDuel Sports Network Detroit, NBC Sports Bay Area California
Athletics starting pitcher	Luis Severino (2-7, 4.42 ERA)
Tigers starting pitcher	Tarik Skubal (8-2, 2.06 ERA)

Athletics vs Tigers latest injuries

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Written by:
Sean Tomlinson

Sean Tomlinson has been in the sports media wilderness since 2009, and he joined Sportsbook Review in 2021. His work has been referenced in The New York Times and Forbes. He's also made appearances on The Fan 590 and TSN 1050. Sean is a regular bettor who places bets daily while using a handful of books. Most frequently, he uses FanDuel and bet365 due to the quality experience on those apps. While he'll often take an analytical approach, Sean enjoys the fun, recreational side of betting too, and embraces alternative markets on events like the Westminster Dog Show or Eurovision, or the many novelty props tied annually to the Super Bowl, for example. Beyond sports, Sean is also interested in the betting markets tied to politics, and especially those connected to American elections. He sees betting as a way to explore and engage in a deeper way, and takes that same view to his work. He plays poker periodically too, and is an avid fantasy sports player. Sean also previously spent time with Bleacher Report and theScore, all after earning his media studies degree from the University of Guelph-Humber.