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Alabama wide receiver Ryan Williams carries the ball after a reception against Missouri. The Crimson Tide's matchup with LSU is one of the can't-miss games in our college football Week 11 predictions.
Alabama wide receiver Ryan Williams carries the ball after a reception against Missouri. Photo by Butch Dill via Imagn Images.

Our Week 11 college football predictions don't just mark the return of #MACtion, it's also full of massive games that will impact the College Football Playoff selection committee's rankings.

With a Week 11 schedule full of matchups involving AP Top 25 teams, this Saturday's slate is one of the best of the year.

College football picks & predictions Week 11

Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Don't miss the rest of our Week 11 college football picks.

College football odds for Saturday

Florida State vs. Notre Dame odds

Prediction: Notre Dame Over 34.5 points (-105 via DraftKings) ⭐⭐⭐⭐

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Pick made by Gabe Henderson

  • When: Saturday, Nov. 9 (7:30 p.m. ET)
  • Where: Notre Dame Stadium (South Bend, Ind.)
  • How to watch: NBC
  • Moneyline: Florida State (+1200) | Notre Dame (-2400)
  • Spread: Florida State +26 (-110) | Notre Dame -26 (-110)
  • Total: 42.5 (-110/-110)

Alabama vs. LSU odds

Prediction: LSU second-half moneyline (+130 via DraftKings)⭐⭐⭐⭐

Pick made by Gabe Henderson

  • When: Saturday, Nov. 9 (7:30 p.m. ET)
  • Where: Tiger Stadium (Baton Rouge, La.)
  • How to watch: ABC
  • Moneyline: Alabama (-148) | LSU (+124)
  • Spread: Alabama -3 (-105) | LSU +3 (-115)
  • Total: 58.5 (-108/-112)

Nevada vs. Boise State odds

Boise State running back Ashton Jeanty running against San Diego State. Jeanty is the focus of our Week 11 college football predictions.  
Boise State running back Ashton Jeanty runs against San Diego State. Photo by Brian Losness via Imagn Images.
  • When: Saturday, Nov. 9 (8 p.m. ET)
  • Where: Albertsons Stadium (Boise, Idaho)
  • How to watch: FOX
  • Moneyline: Nevada (+1100) | Boise State (-2100)
  • Spread: Nevada +24 (-112) | Boise State -24 (-108)
  • Total: 60.5 (-112/-108)

College football picks roundup: Week 11

College football betting odds pages

Here are our best college football betting sites:

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