NFL Picks, Predictions Roundup Week 18: Best Bets for the Final Week of the Season

Tracking our NFL betting experts' top picks for every game each week of the 2022 NFL season.

As the playoffs approach, the final push is underway. Check out our top NFL picks for Week 18 based on the best odds.  

Our NFL betting experts have been tracking the odds and lines for Week 18, and they offer their top ATS, O/U, and prop plays for the week below. We're also breaking down the betting with our Week 18 upset picks, against-the-spread power rankings, teaser picks, parlay picks, Over/Under picks, best bets, touchdown scorer prop picks and trends to know.

All season we'll also be keeping an eye on the odds to win the 2023 Super Bowl and each of the major NFL awards.

Editor's note: Hey Ohio! Welcome to legal sports betting. Check out the best sites for Ohio sports betting and the best Ohio sportsbook promos!

NFL Picks Week 18: Sunday

Giants vs. Eagles

Best bet: Under 43 (-110 via BetMGM)

Cowboys vs. Commanders

Best bet: Commanders +7 (-110 via FanDuel)

Chargers vs. Broncos

Best bet: Under 40 (-110 via DraftKings)

Rams vs. Seahawks

Best bet: Rams +6 (-110 via BetMGM)

Cardinals vs. 49ers

Best bet: 49ers Over 27.5 points (BetMGM +110)

Lions vs. Packers

Best bet: Amon-Ra St. Brown Over 69.5 receiving yards (-115 via DraftKings)

Top Week 18 NFL Picks

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