UConn vs. Creighton Prediction, Odds & Score Picks: Big East Conference Semifinal Best Bets

A spot in the Big East title game will be up for grabs when UConn and Creighton square off on Friday. Tipoff from Madison Square Garden in New York is at 9 p.m. ET on Friday (FOX).

The Huskies are 3.5-point favorites after winning last year’s conference title (and the previous two national championships), but Dan Hurley’s team isn’t nearly as dominant this time around. Creighton split the regular-season series with UConn this year.

💰 UConn vs. Creighton predictions, expert picks & best bets: Big East Conference Semifinal

Here are my best UConn vs. Creighton predictions, expert picks, and best bets today for the Big East Conference Semifinal with my pick confidence based on a 1-to-5-star scale. Be sure to check out the rest of our college basketball picks along with our guide on how to bet on college basketball.

• Against the spread pick: Creighton +4 (-110 via Caesars) vs. UConn ⭐⭐⭐⭐
• My best player prop bet: Steven Ashworth Over 5.5 assists (-118 via BetMGM) ⭐⭐⭐⭐
• Exact score prediction: UConn 72, Creighton 70 (+17000 via DraftKings)

👉 Check out our latest March Madness projections with our SBR Bracketology ahead of the NCAA Tournament!

🏀 UConn vs. Creighton ATS prediction & best player prop bet pick

Here's why I'm betting on Creighton to cover the spread (+4) while targeting Steven Ashworth Over 5.5 assists (-118) as my best player prop bet pick for today:

✅ Creighton to cover the spread (+4) ⭐⭐⭐⭐

This is a game that Creighton could win outright based on the coin-flip projections across the board.

• Kenpom: UConn 73, Creighton 72
• EvanMiya: UConn 72.6, Creighton 70.7
• Bart Torvik: UConn 73, Creighton 72

The Huskies’ recent postseason success has provided value on the Bluejays. These teams are neck-and-neck, and I’m happy to take the full 4-point spread, even after a double OT performance by Creighton.

📊 Best odds: -110 via Caesars (bet $10 to win $9.09)

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🔥 Steven Ashworth Over 5.5 assists ⭐⭐⭐⭐

Creighton has value as an underdog, putting Ashworth’s assists props on the menu after he recorded five dimes in 39 minutes last night. He ranks seventh in the nation with an average of seven assists per game.

Ashworth cleared this mark in both meetings against UConn. He recorded 16 assists across those two matchups. This line is as high as -125 at DraftKings, meaning BetMGM provides a discount for bettors.

📊 Best odds: -118 via BetMGM (bet $10 to win $8.47)

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🎯 Expert UConn vs. Creighton score prediction & AI projections

🔮 Expert score prediction: UConn 72, Creighton 70
🤖 AI score prediction: UConn 74, Creighton 71

🔮 Expert score prediction: UConn 72, Creighton 70

I’m not buying the market’s reaction to the spread following Creighton’s double-time game last night. These are college kids, after all. I predict Creighton will cover the spread (+4) in a hard-fought loss to UConn, 72-70.

📊 Best odds: +17000 via DraftKings (bet $10 to win $1,700)

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🤖 AI score prediction: UConn 74, Creighton 71

(Score prediction and analysis via ChatGPT - a large language model from OpenAI. While ChatGPT is not specifically designed for predicting sporting events, it can spot trends or insights that bettors might overlook.)

🖥️ AI predictions for UConn vs. Creighton

The projected final score is UConn 74, Creighton 71.

• Win probability: UConn 58.2%, Creighton 51.8%
• Projected total points: 145

🤔 Betting takeaway: ChatGPT's AI score prediction leans toward Creighton covering the spread (+4) and a total of Over 139.5 points.

📊 Live UConn vs. Creighton odds & latest betting splits

Here are the latest odds for UConn vs. Creighton, which update live in real time. You can also check out our NEW college basketball player prop odds tool for the latest college basketball odds on any market across legal sportsbooks in your region.

🔢 VUConn vs. Creighton opening odds

Here's a look at the opening odds for UConn vs. Creighton according to BetMGM.

• Spread: UConn -3.5 (-118) | Creighton +3.5 (-102)
• Moneyline: UConn -185 | Creighton +150
• Over/Under: Over 139.5 (-110) | Under 139.5 (-110)

🏆 Who will win UConn vs. Creighton?

As of 10:20 a.m. ET, UConn is favored by 3.5 points to beat Creighton with moneyline odds of -185 at BetMGM, which suggests a 64.91% win probability for the Huskies. We're predicting a 72-70 win for UConn as our final score projection.

So far, 54% of bettors have wagered against the spread on UConn -3.5, while 51% of bettors expect the game to finish Under the projected total of 139.5 points.

📺 How to watch UConn vs. Creighton tonight

📅 Date: Friday, March 14, 2025
🕗 Time: 9 p.m. ET
📍 Location: Madison Square Garden (New York)
📺 TV: FOX
💻 Streaming: FOX Sports

❓UConn vs. Creighton FAQs

Who's favored to win the Big East Conference tournament?

St. John's is favored to win the Big East tournament.

Who is favored to win UConn vs. Creighton?

UConn is -185 on the moneyline, which carries an implied win probability of 64.91%.

What are the betting odds for UConn vs. Creighton?

The latest spread is UConn -3.5 (-110) | Creighton +3.5 (-110), with a total of 139.5 points (-110).

What will be the final score of UConn vs. Creighton?

We're predicting a final score of UConn 72, Creighton 70, entering tonight's matchup at Madison Square Garden.

What time is UConn vs. Creighton tonight?

Tipoff for UConn vs. Creighton is tonight at 9 p.m. ET.

⛹️ Best college basketball betting sites

Looking to bet on college basketball tonight? Here are our best March Madness betting sites as determined by our expert team at Sportsbook Review, along with our best March Madness betting promos ahead of the NCAA Tournament.

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