NBA Picks & Predictions Today: Best Bets, Odds for Every Game Tonight (Oct. 22)

Last Updated: October 22, 2025 9:02 PM EDT âĸ 2 minute read X Social Google News Link

After a riveting opening night, we're offering our NBA picks and predictions for Wednesday, Oct. 22, with our best NBA expert picks and live odds for all 12 games tonight - including our best player prop bets for Cooper Flagg's debut in Dallas.
đŽ NBA predictions today: Oct. 22
See all of our NBA picks today based on the latest NBA odds.
- Best NBA player prop bets tonight
- 76ers vs. Celtics player prop bets
- Heat vs. Magic player prop bets
- Cavaliers vs. Knicks player prop bets
- Spurs vs. Mavericks player prop bets
- Cooper Flagg player props & odds
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đ San Antonio Spurs vs. Dallas Mavericks (9:30 PM ET)
See the Spurs vs. Mavericks odds for line history, betting trends, and matchup info.
đ Live Spurs vs. Mavericks odds
âšī¸ââī¸ Spurs vs. Mavericks player props
Our NBA expert Corey Scott expects a slow start from Victor Wembaynama in his Spurs vs. Mavericks player prop bets as the San Antonio star returns from injury. He's also focusing on the No. 1 pick with his Cooper Flagg player props & odds ahead of his debut.
đē How to watch Spurs vs. Mavericks
- Tipoff: 9:30 p.m. ET
- Location: American Airlines Center (Dallas)
- TV: Bally Sports Southwest
đ Sacramento Kings vs. Phoenix Suns (10 PM ET)
See the Kings vs. Suns odds for line history, betting trends, and matchup info.
đ Live Kings vs. Suns odds
đē How to watch Kings vs. Suns
- Tipoff: 10 p.m. ET
- Location: Mortgage Matchup Center (Phoenix, Ariz.)
- TV: ESPN
đ Minnesota Timberwolves vs. Portland Trail Blazers (10 PM ET)
See the Timberwolves vs. Trail Blazers odds for line history, betting trends, and matchup info.
đ Live Timberwolves vs. Trail Blazers odds
đē How to watch Timberwolves vs. Trail Blazers
- Tipoff: 10 p.m. ET
- Location: Moda Center (Portland, Ore.)
- TV: Root Sports Northwest
đĩ Most popular NBA bets today
NBA betting insights for Wednesday courtesy of BetMGM; data based on ticket count.
Most popular ATS picks
- Cavaliers -1.5 vs. Knicks
- Pistons -3.5 vs. Bulls
- Knicks +1.5 vs. Cavaliers
- Celtics -3.5 vs. 76ers
- Timberwolves -4.5 vs. Trail Blazers
Most popular O/U picks
- Cavaliers vs. Knicks Over 218.5
- Heat vs. Magic Under 206.5
- 76ers vs. Celtics Under 229.5
- Heat vs. Magic Over 214.5
- Cavaliers vs. Knicks Under 226.5
Most popular player prop bets
- Kristaps Porzingis (ATL) Over 17.5 points vs. Raptors (-120)
- Derrick White (BOS) Under 4.5 three-pointers made vs. 76ers (-160)
- Tyus Jones (ORL) Under 1.5 three-pointers made vs. Heat (-145)
- Brice Sensabaugh (UTA) Over 2.5 rebounds vs. Clippers (-110)
- Myles Turner (MIL) Over 1.5 three-pointers made vs. Wizards (-155)
Most popular bets to score first field goal
- Ivica Zubac (LAC) vs. Jazz (+675)
- Joel Embiid (PHI) vs. Celtics (+220)
- Ja Morant (MEM) vs. Pelicans (+290)
- LaMelo Ball (CHA) vs. Nets (+700)
- Victor Wembanyama (SAS) vs. Mavericks (+450)
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