NBA Picks & Predictions Today: Best Bets, Odds for Every Game Tonight (Oct. 22)

We're offering our best NBA picks and predictions today with odds for every game of a packed 12-game slate.
NBA Picks & Predictions Today: Best Bets, Odds, Player Props for Wednesday (Oct. 22)
Pictured: San Antonio Spurs forward-center Victor Wembanyama (1) reacts before a timeout. Photo by Scott Wachter / Imagn Images.

After a riveting opening night, we're offering our NBA picks and predictions for Wednesday, Oct. 22, with our best NBA expert picks and live odds for all 12 games tonight - including our best player prop bets for Cooper Flagg's debut in Dallas.


🔮 NBA predictions today: Oct. 22

See all of our NBA picks today based on the latest NBA odds.

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🏀 San Antonio Spurs vs. Dallas Mavericks (9:30 PM ET)

See the Spurs vs. Mavericks odds for line history, betting trends, and matchup info.

📈 Live Spurs vs. Mavericks odds

â›šī¸â€â™‚ī¸ Spurs vs. Mavericks player props

Our NBA expert Corey Scott expects a slow start from Victor Wembaynama in his Spurs vs. Mavericks player prop bets as the San Antonio star returns from injury. He's also focusing on the No. 1 pick with his Cooper Flagg player props & odds ahead of his debut.

đŸ“ē How to watch Spurs vs. Mavericks

  • Tipoff: 9:30 p.m. ET
  • Location: American Airlines Center (Dallas)
  • TV: Bally Sports Southwest

🏀 Sacramento Kings vs. Phoenix Suns (10 PM ET)

See the Kings vs. Suns odds for line history, betting trends, and matchup info.

📈 Live Kings vs. Suns odds

đŸ“ē How to watch Kings vs. Suns

  • Tipoff: 10 p.m. ET
  • Location: Mortgage Matchup Center (Phoenix, Ariz.)
  • TV: ESPN

🏀 Minnesota Timberwolves vs. Portland Trail Blazers (10 PM ET)

See the Timberwolves vs. Trail Blazers odds for line history, betting trends, and matchup info.

📈 Live Timberwolves vs. Trail Blazers odds

đŸ“ē How to watch Timberwolves vs. Trail Blazers

  • Tipoff: 10 p.m. ET
  • Location: Moda Center (Portland, Ore.)
  • TV: Root Sports Northwest

đŸ’ĩ Most popular NBA bets today

NBA betting insights for Wednesday courtesy of BetMGM; data based on ticket count.

Most popular ATS picks

  • Cavaliers -1.5 vs. Knicks
  • Pistons -3.5 vs. Bulls
  • Knicks +1.5 vs. Cavaliers
  • Celtics -3.5 vs. 76ers
  • Timberwolves -4.5 vs. Trail Blazers

Most popular O/U picks

  • Cavaliers vs. Knicks Over 218.5
  • Heat vs. Magic Under 206.5
  • 76ers vs. Celtics Under 229.5
  • Heat vs. Magic Over 214.5
  • Cavaliers vs. Knicks Under 226.5

Most popular player prop bets

  • Kristaps Porzingis (ATL) Over 17.5 points vs. Raptors (-120)
  • Derrick White (BOS) Under 4.5 three-pointers made vs. 76ers (-160)
  • Tyus Jones (ORL) Under 1.5 three-pointers made vs. Heat (-145)
  • Brice Sensabaugh (UTA) Over 2.5 rebounds vs. Clippers (-110)
  • Myles Turner (MIL) Over 1.5 three-pointers made vs. Wizards (-155)

Most popular bets to score first field goal

  • Ivica Zubac (LAC) vs. Jazz (+675)
  • Joel Embiid (PHI) vs. Celtics (+220)
  • Ja Morant (MEM) vs. Pelicans (+290)
  • LaMelo Ball (CHA) vs. Nets (+700)
  • Victor Wembanyama (SAS) vs. Mavericks (+450)

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