Indy 500 Odds: Pato O'Ward, Alex Palou the Co-Favorites Ahead of Today's Race

Pato O'Ward and Alex Palou are the Indy 500 odds co-favorites as we dive into the updated odds while getting AI to chip in with its pick.
Indy 500 Odds
Pictured: Chip Ganassi Racing driver Alex Palou chats in the pit area before the 109th running of the Indianapolis 500 at Indianapolis Motor Speedway. Photo by Kristin Enzor via Imagn Images

Alex Palou and Pato O'Ward are the Indy 500 odds co-favorites at our best sports betting sites ahead of today's race at the Brickyard (12:45 p.m. ET, FOX). 

Josef Newgarden, the two-time defending Indy 500 winner, has seen his odds shorten in the lead-up to the race despite dealing with penalties for illegal modifications to his car and starting at the back of the grid. 

Robert Schwartzman impressed by taking pole, the first time a rookie has done so since 1983. 

πŸ“Š Indy 500 odds 2025

Odds from FanDuel as of Sunday, May 25.

Driver FanDuel Implied probability Profit on $10 bet
Alex Palou +440 18.52% $44
Pato O'Ward +440 18.52% $44
Scott Dixon +650 13.33% $65
Josef Newgarden +750 11.76% $75
Takuma Sato +850 10.53% $85
Scott McLaughlin +1000 9.09% $100
Will Power +1700 5.56% $170
Robert Shwartzman +1900 5% $190
Felix Rosenqvist +1900 5% $190
Kyle Larson +1900 5% $190
David Malukas +2200 4.35% $220
Colton Herta +2500 3.85% $250
Christian Lundgaard +2500 3.85% $250
Helio Castroneves +3000 3.23% $300
Marcus Ericsson +3000 3.23% $300
Santino Ferucci +3000 3.23% $300
Kyle Kirkwood +3000 3.23% $300
Alexander Rossi +3000 3.23% $300
Conor Daly +3600 2.7% $360
Ed Carpenter +7000 1.41% $700
Ryan Hunter-Reay +7000 1.41% $700
Graham Rahal +7000 1.41% $700
Marcus Armstrong +8000 1.23% $800
Louis Foster +8000 1.23% $800
Nolan Siegel +8000 1.23% $800
Marco Andretti +10000 0.99% $1,000
Christian Rasmussen +10000 0.99% $1,000
Sting Ray Robb +10000 0.99% $1,000
Rinus Veekay +10000 0.99% $1,000
Callum llott +12000 0.83% $1,200
Kyffin Simpson +12000 0.83% $1,200
Jack Harvey +15000 0.66% $1,500
Delvin DeFrancesco +20000 0.50% $2,000

πŸ€– Indy 500 AI prediction

I had a conversation with ChatGPT, a large language model chatbot from OpenAI, and asked for its best Indy 500 AI pick to win. Please note that ChatGPT is not an experienced bettor, and it should be used only to gather additional information and insights.

πŸ† Alex Palou (+600 via FanDuel)

Here's why Alex Palou (+600) is the pick from ChatGPT to win the 2025 Indy 500.

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🏎️ Unparalleled season dominance: Palou has been the standout driver in the 2025 IndyCar season, securing four victories in the first five races. This dominant performance has granted him a substantial lead in the championship standings, underscoring his exceptional form and consistency. His recent triumph on the Indianapolis Motor Speedway's road course further highlights his adaptability and prowess at this venue.

🏎️ Consistent excellence at the Indy 500: While Palou is yet to clinch an Indy 500 victory, his track record at the event is impressive. He has achieved three top-five finishes over his five appearances, demonstrating his competitiveness and skill on the iconic oval. Notably, he's previously qualified on both the front row and pole position, indicating his capability to perform under the unique pressures of this race.

🏎️ Strategic advantage with Honda: The 2025 season introduces hybrid power units, and Honda-powered teams have shown a strategic focus on qualifying performance. This emphasis has resulted in Honda securing 11 of the top 12 starting positions for the Indy 500, providing a significant advantage in track position. Palou, driving for Chip Ganassi Racing with Honda power, benefits directly.

🏁 2025 Indy 500 Starting Grid

Here is a look at top 10 in the starting grid for the 2025 Indy 500, as well as other highlights. 

Pole. Robert Schwartzman
2. Takuma Sato 
3. Pato O'Ward
4. Scott Dixon
5. Felix Rosenqvist
6. Alex Palou
7. David Malukas
8. Christian Lundgaard
9. Marcus Ericsson
10. Scott McLaughlin
32. Josef Newgarden

πŸ“Ί How to watch the 2025 Indy 500

πŸ“… Race date: Sunday, May 25
πŸ•’ Start time: 12:45 p.m. ET
πŸ“ Track: Indianapolis Motor Speedway (Indianapolis, IND)
πŸ“Ί TV: FOX
πŸ’» Streaming: Fubo
β˜€οΈ Weather: 64 degrees, 9-mph to 14-mph winds, 30% chance of precipitation

πŸ†Past Indy 500 winners

Driver Year
Josef Newgarden 2024
Josef Newgarden 2023
Marcus Ericsson 2022
Helio Castroneves 2021
Takuma Sato 2020
Simon Pagenaud 2019
Will Power 2018
Takuma Sato 2017
Alexander Rossi 2016
Juan Pablo Montoya 2015
Ryan Hunter-Reay 2014

🏎️ Motorsports betting odds pages

❓Indy 500 FAQs

Who is favored to win the 2025 Indy 500?

Pato O'Ward is the narrow favorite over Alex Palou while getting +500 odds, which implies a 16.67% probability.

When is the 2025 Indy 500?

The 2025 Indy 500 will take place on Sunday, May 25.

Where is the Indy 500?

The race is held annually at the Indianapolis Motor Speedway in Speedway, Ind.

Who won the 2024 Indy 500?

Josef Newgarden won the 2024 running of the Indy 500 after overtaking Pato O'Ward on the final lap, becoming the fourth driver in the history of the race to win on a last-lap pass. Newgarden also took the Indy 500 for the second straight year. He's the sixth driver to earn back-to-back victories, and the first since Helio Castroneves in 2001-02.

Why does the Indy 500 winner drink milk?

The tradition started when Louis Meyer requested a glass of buttermilk after winning his second Indy 500 race in 1933. He did so again following his third win in 1936, and he was photographed swigging from the bottle of milk while holding up three fingers to signify the third triumph.

A local dairy company - unaware Meyer was drinking buttermilk - offered a bottle of milk to the winners of future races. Milk has been presented each year since then, apart from 1947 to 1955. 

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